Science, Leiden Institute of Advanced Computer Science (LIACS)

Walsh

This is the first special issue of any organisation studies journal on food labour. Why is this a big deal? In this Introduction, we argue that the field should pay much more attention to the agri-food system and the work that goes into producing, distributing and consuming foodstuff. Food is such an…

Xinrong Ma defended her thesis on 13 February 2018

Grasseni's contribution to this special feature on food cultures, food systems, and agriculture in Europe builds upon her ongoing project Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

Analysis of drug adversity

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Lecture

Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

SLAVES TO THE SYSTEM: Locating Responsibility for Forced Expatriate Labour Practices by the Democratic People’s Republic of Korea (DPRK)

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Think tanks have proliferated in most Western democracies over the past three decades and are often considered to be increasingly important actors in public policy. Still, their precise contribution to public policy remains contested.

A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

Every day, Veilig Thuis employees receive hundreds of reports of domestic violence and child abuse. Despite their efforts, they are heavily criticised due to the long waiting times. Mariëlle Bruning, Professor of Children and the Law, appeared on talk show ‘Eva’ to discuss the Dutch care and welfare…

Using artificial intelligence is more complicated for the government than for companies. Bram Klievink, Professor of Public Administration, aims to identify the problems and find solutions.

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

PhD defence

The potential of liposomal cancer vaccines

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Homicide engenders broad moral concerns in society, and its aftermath can be understood as a barometer for criminal justice policy. Of all homicides committed, however, only some lead to arrest, to prosecution and ultimately to conviction in court.

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Lodewijk Petram, author of the book 'The World's First Stock Exchange', discussed the rise of the Amsterdam stock exchange in the 17th century in the ninth Hazelhoff Guest Lecture.

What is Interaction between Legal Systems (ILS) and what does it entail as research profile area at Leiden Law School? More on this at the kick-off event of ILS 2.0. This will take place on Wednesday 26 October 15.00 – 17.00 in the Grotiuszaal (A051 KOG). The afternoon will be closed with drinks at…

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

PhD defence

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

What is the origin of solar systems?

On 5 October, Katherine Filesia defended the thesis 'Speaking the same language: the introduction of the Anglo-American trust into the Dutch legal system'. The doctoral research was supervised by Pim Huijgen and Frans Sonneveldt.

Promotor: Prof.dr. M. Danhof

The languages of the Mbam-et-Inoubou District of the Centre Region of Cameroon have a unique position in Bantu linguistics. Being in between