In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

PhD defence

An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

OBJECTIVES: To determine whether the lipid/protein ratio and the total dry SC mass per surface area are related with the skin barrier function of controls and AE patients.

Fred Janssen is curious about how best to teach students and students to gain a good understanding of complex ‘swamp situations’. This is the subject of his inaugural lecture as Professor of Science Education at the ICLON and the Faculty of Science. Inaugural address 19 June 2017.

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Promotor: E.F. Smets Co-promotor: J. Geml

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

What are the precise identities, possibilities and current practice examples of the various time frames in music and what bearings do they have individually and in combinations on the speed of the music?

This research will focus on the relationship between the musical structure and musical time in the performance of 19th century music.

Morality, mathematics, geometry, geography, music, navigation, and language are traditionally viewed as uniquely human cultural achievements and abilities. The study of their development and variation is classified as part of the humanities and social sciences. These fields have been mainly studied…

Fatemeh (Simin) Tabassi Mofrad has recently received a project grant (€ 25,000) from LUF/Gratama Foundation for her ideas in investigating sex-by-genotype interactions in brain functions. She has a multidisciplinary research perspective which enables her to look at research issues from different angles.…

On 4 and 5 November 2021 an ICOG-workshop will be held on the cognitive turn in history. It is possible to attend this workshop online. The participants of the workshop are cultural and intellectual historians of the pre-modern periods and/or of the historiography of academia from a long-term perspective,…

Birds sing to be heard, but how do they cope with increasing noise levels? Which species persist in cities and why? And do they thrive or suffer in the urban soundscape?

How is social cognition shaped by our knowledge of language and stories?

In September 2019, Manon Mulckhuyse will start a position as assistant professor in the Cognitive Psychology Unit.

Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963

Are disturbances to the brain, such as Alzheimer's or autism, linked to specific defects in the underlying communication networks in the brain? If this is the case, subtle changes in the networks can act as a marker for brain disturbances. Neuroscientist Serge Rombouts will be investigating this, together…

To what end and how does Plautus constantly underline the Helleni(sti)c provenance of his art? How does this aspect relate the author’s originality?

Quasicrystals are crystals with ‘impossible’ five-fold symmetries, which nevertheless were synthesized in the lab in 1982. Paul J. Steinhardt helped figure out their structure, but he didn’t stop at that.

An international partnership of brain researchers from 35 research centres - from the US to China - including the Leiden Institute for Brain and Cognition (LIBC), has collected resting-state functional MRI data from more than 1400 healthy volunteers and put the information online so that it is available…

On 7 November 2018, Catherine Harwood defended her thesis 'Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International Legal Order'. The doctoral research was supervised by Prof. dr. L.J. Van den Herik and Prof.…

Based on the results of a language-switching experiment, PhD candidate Fatemeh (Simeen) Tabassi Mofrad MA and Professor Niels Schiller have discovered that the traditional categorisation of brain areas is not sufficient. They published their research findings in the scientific journal NeuroImage.

The Palaeolithic period extends from the earliest stone tools (and in Europe, earliest occupation) to the beginning of the current warm period.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

This historical study argues that the Mandaean religion originated under Sasanid rule in the fifth century, not earlier as has been widely accepted. It analyzes primary sources in Syriac, Mandaic, and Arabic to clarify the early history of Mandaeism.

Promotor: C.J. ten Cate

Archaeologists and students from Leiden University and local volunteers have found a Roman camp in the woods near Ermelo. The camp is four kilometres away from another Roman fortification discovered some time ago. This confirms the idea that the Romans would also often explore beyond the boundaries…

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

From 5 to 7 June, the conference "The Senses, Cognition, and the Body in Medieval Devotional Practices" will take place at the University of Padova. The conference programme can be found below. The conference can be attended virtually through the registration link below.

Dementia is a progressive disease, diagnosed at a relatively late stage when intervention may not be effective. Aim of the research is to study scans of brain networks to help discover the early network changes related to dementia. Early diagnosis may benefit effectiveness of future treatment.

An Ancient Egyptian System of Workmen’s Identity Marks

Which intervention technique is more effective in reducing public speaking anxiety in children aged 9 – 12 years, exposure or restructuring cognitions?