1,653 search results for “molecular genetics” in the Public website
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Bioactive Molecules in Microbial Sciences
Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Break-through in the genetic modification of plants
A collaboration between the IBL and LUMC has resulted in the discovery that the polymerase theta enzyme is essential for the integration of Agrobacterium T-DNA into the genome of plants. The finding means a break-through for the development of more efficient systems for targeted genome modification…
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Expertise
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…
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How a Spanish post-doc brings her expertise in chemistry to Leiden genetics
Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Mario van der Stelt appointed Professor of Molecular Physiology
Mario van der Stelt has been appointed Professor of Molecular Physiology at the Leiden Institute of Chemistry with effect from 1 November 2017.
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Quantitative biology of polar auxin transport and plant development
The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…
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Transfer of graphene by molecular caging
Chemists developed a new graphene-transferring method which makes use of cyclohexane. This new method leaves less impurities on graphene, is easier to handle than current methods and is widely applicable in graphene research. The publication will be on the cover of the journal ACS Central Science late…
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Efficacy of Self-management training in adolescents and adults with Klinefelter syndrome (XXY)
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Serena Viti is our new professor of Molecular Astrophysics
The Leiden Observatory has appointed a new professor. Selena Viti will hold a chair in Molecular Astrophysics. Viti will build a research group that combines different research techniques to unravel the secrets of local and external galaxies. ‘My main ambition is to change the way scientists interpret…
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
- Practical Information
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The Leiden Family Lab study on Social Anxiety Disorder
Social anxiety runs in families, but the neurobiology underlying this genetic vulnerability is until now largely unknown. The unique Leiden Family Lab study on Social Anxiety Disorder (LFLSAD) aims to broaden our knowledge with respect to this genetic susceptibility.
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UV Photodesorption and Photoconversion of Interstellar Ices
This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.
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igraph - To modernize the igraph interfaces to make network analysis easier
igraph development focused on improving the most-used interfaces, which are Python, R, and Mathematica. Additionally, the developers aim to make the library and the interfaces easier to maintain, focusing on long-term sustainability. This ensures that igraph continues to be a useful tool for network…
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Louie Krol
Science
l.krol@cml.leidenuniv.nl | +31 71 527 2727
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Laura Heitman appointed as Professor of Molecular Pharmacology
As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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Electronic spectroscopy of molecules of astrophysical interest
This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
- Lectures
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Wouter Staal
Faculteit der Sociale Wetenschappen
w.g.staal@fsw.leidenuniv.nl | +31 71 527 8843
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Simeen Tabassi Mofrad
Faculty of Humanities
f.tabassi.mofrad@hum.leidenuniv.nl | +31 71 527 2125
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets
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Phylogeny and species delimitation within the moss genus Dicranum Hedw.
Promotor: Prof.dr. E. Smets, Dr. M. Stech
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Specificity and side-effects of mutagenesis by CRISPR/Cas9 -induced breaks in plants
Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?
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Patterns of coral species richness and reef connectivity in Malaysia
Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema
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Minute molecular movements might lead to more efficient biofuel cells
Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.
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Holland Research School of Molecular Chemistry awards PhD project to David Klein
Leiden based chemistry student and chess grandmaster proposes molecular system for development of artificial leaf
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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Remko Offringa appointed Professor in the field of Plant Developmental Genetics
Remko Offringa has been appointed Professor in the field of Plant Developmental Genetics within the Faculty of Science at the Institute of Biology Leiden (IBL) from the 1st of April 2017. Offringa’s research focuses on the role of the plant hormone auxin in controlling plant growth and development,…
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Molecular Biology for Physics will NOW start on Monday 5 February!
Please note that the course Molecular Biology for Physics will start on Monday 5 February. Please check the schedules for the time and location!
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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In shape for photoregulation
How does the photoregulation mechanism work in detail?
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The formation of complex organic molecules in dense clouds-Sweet results from laboratory
Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.
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Jorinde Nuytinck
Science
jorinde.nuytinck@naturalis.nl | +31 71 527 2727
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Xinya Pan
Science
x.pan@biology.leidenuniv.nl | +31 71 527 4791
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Francesco Buda
Science
f.buda@lic.leidenuniv.nl | +31 71 527 5723
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Niels van der Windt
Science
n.van.der.windt@cml.leidenuniv.nl | +31 71 527 2727
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Pieter Reitsma
Faculteit Geneeskunde
p.h.reitsma@lumc.nl | +31 71 526 6985
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…