2,630 search results for “media drug violence” in the Public website
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel
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Travelling patterns on Discrete Media
This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.
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LEiden university NexuS of Arts | Media | Politics
The purpose of LENS is to foster, coordinate and support research of visual media of analog and digital photography, film, and video, and the visual arts.
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EU H2020 RISE Social Media Analytics
LIACS is a partner in RISE_SMA, an interdisciplinary, international network combining excellent scholars and practitioners to enable vigorous knowledge sharing and to develop solutions for contemporary challenges for Social Media Analytics (SMA).
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The effect of trial by media
The trial of Dutch rapper Ali B is receiving massive media attention. Party due to himself, the trial can be followed by the public. How will this affect the upcoming verdict? Dutch newspaper ‘De Volkskrant’ spoke to legal scholars and experts including Jan de Keijser.
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The Dutch and English East India Companies: Diplomacy, Trade and Violence in Early Modern Asia
The Dutch and English East India Companies were formidable organizations that were gifted with expansive powers that allowed them to conduct diplomacy, wage war and seize territorial possessions. But they did not move into an empty arena in which they were free to deploy these powers without resista…
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Freedom and the Fifth Commandment. Catholic priests and political violence in Ireland, 1919-21
A new paperback edition of Brian Heffernan's book Freedom and the Fifth Commandment. Catholic priests and political violence in Ireland, 1919-21 was published by Manchester University Press in September 2016.
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New track 'Governance of Violence' addresses need to conduct violence specific studies
The sixth specialisation of the Master Crisis and Security Management (CSM) will start in September 2023: Governance of Violence. Coordinator of this track is Professor Marieke Liem. She talks about the how and why of this new track and the importance of research in and knowledge of the nature and scope…
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Disinformation and Strategic Communication in Global Media
From fake news to COVID-19 conspiracies, debates about truth claims have become more prominent during the past decade. Taking a global, comparative perspective, the minor Disinformation and Strategic Communication in Global Media focuses on the broad spectrum of contested narratives subsumed under the…
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Staging the Archive: Art and Photography in the Age of New Media
Staging the Archive: Art and Photography in the Age of New Media is dedicated to art practices that mobilize the model of the archive, demonstrating the ways in which such archival artworks probe the possibilities of what art is and what it can do.
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Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
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namic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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How to scale clearance from adults to children for drugs undergoing hepatic metabolism?
The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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generation human IPSC-derived reporter systems for image-based analysis of drug adversity
Analysis of drug adversity
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Politics of Withdrawal Media, Arts, Theory
'Politics of Withdrawal' considers the significance of practices and theories of withdrawal for radical thinking today.
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Lingyun Lai
Faculty of Humanities
l.lai@hum.leidenuniv.nl | +31 71 527 2727
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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In the Media
Our research regularly receives attention in the (Dutch) popular media. Here is an overview.
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Personalised pharmacotherapy in paediatric epilepsy : the path to rational drug and dose selection
The path to rational drug and dose selection
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A community effort to assess and improve drug sensitivity prediction algorithms
Source: Nature Biotechnology, Volume 2014, Issue June (2014)
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Cytochrome P450 3A-mediated first-pass and systemic drug metabolism in children
From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.
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throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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Hildert Bronkhorst
Science
h.bronkhorst@biology.leidenuniv.nl | +31 71 527 4964
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Media studies: Film and Photographic Studies
Are you thinking about studying Film and Photographic Studies? Learn more and watch the introduction video.
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Media studies: Cultural Analysis: Literature and Theory
Are you thinking about studying Cultural Analysis: Literature and Theory? Learn more and watch the introduction video.
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Adriaan van der Weel
Faculty of Humanities
a.h.van.der.weel@hum.leidenuniv.nl | +31 71 527 2727
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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Jeanette Satink
Faculteit Rechtsgeleerdheid
a.e.j.satink@law.leidenuniv.nl | +31 71 527 2727
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conflict minerals: The complex links between artisanal gold mining and violence
Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence
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The impact of obesity on the pharmacokinetics of drugs in adolescents and adults
Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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3 October University: from Russian DNA to drug-related violence
In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…
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Research Assistant on Law and Human Vulnerability in Social Media 0,8 - 1,0 fte
Law, Institute for the Interdisciplinary Study of the Law, eLaw - Center for Law and Digital Technologies
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Understanding the value of social media metrics for research evaluation
The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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African Oral Literatures, new media and technologies
African oral literatures, new media and technologies: challenges for research and documentation
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Tracing Policy-relevant Information in Social Media: The Case of Twitter before and during the COVID-19 Crisis
This paper written by Vydra and Kantorowicz answers the research question ‘What policy-relevant information does Twitter contain?’ as well as the research question ‘How does this information change between a period of normalcy and a period of crisis?’
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quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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characteristics and immediate situational factors in the outcome of serious violence
Why do certain incidents of serious violence end lethally whereas others do not? What role do personal characteristics of offenders and victims play and how do immediate situational factors influence outcomes?
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Erasmus+ Project on Fact-Checking and Media Literacy
A European cooperation project on disinformation and fact-checking training empowering current and future media and media education professionals, to identify, prevent, and combat fake news spread over digital networks.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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value of semi-physiological models for clearance of renally excreted drugs across the paediatric age range
The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.
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Information activities
Get to know us through our online and in-person events for prospective students!
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Marieke Liem: In the media
Stay tuned for updates on relevant media appearances of Marieke Liem.
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system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Group violence: collective and individual issue
The out of control ‘Project X’ event in Haren, hooligans who arrange to meet up to fight and beach riots at the Hoek van Holland: group violence is increasingly hitting the headlines. Are those who took part seasoned criminals? And what characteristics do group offenders have? PhD defence on 29 September…