8,056 search results for “publication” in the Public website
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Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity
The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.
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Contribute
The editorial board of Inter-Section happily invites contributions from ambitious archaeology students, or recent graduates, of Leiden University’s Faculty of Archaeology. We welcome all sorts of article submissions, as long as they are based on the original work of the author and contribute to the…
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Sustaining the unsustainable? The political sustainability of pensions in Finland and the Netherlands
What makes a pension scheme sustainable? Most answers to this question have revolved around expert assessments of pension schemes’ affordability or adequacy. This study shifts focus from the financial or social sustainability of pension scheme designs to their political sustainability. The key question…
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Looking Beyond Our Similarities
How Perceived (In)Visible Dissimilarity Relates to Feelings of Inclusion at Work
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Centre for Digital Heritage (CDH)
The Centre for Digital Heritage undertakes collaborative international research in the field of Digital Heritage. It is an initiative of the University of York.
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Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
The potential of bioneedles to deliver influenza vaccines was investigated.
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Ethics and copyrights
PAIR stands for ethical publishing and transparency. Below you can read about our commitment to COPE principles, copyright compliance and rigorous peer review ensures the integrity of every article we publish.
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A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action
Source: Mediators Inflamm (2014)
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Embracing the Provinces: Society and Material Culture of the Roman Frontier Regions
Embracing the Provinces is a collection of essays focused on people and their daily lives living in the Roman provinces, c. 27 BC-AD 476. It offers an overview of current research on Roman provinces and frontiers, deconstructing some long-held preconceptions and providing refreshing insights into unexplored…
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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Cultural Anthropology and Development Sociology | Leiden University
Cultural Anthropology and Development Sociology at Leiden University studies the everyday practices of individuals and groups around the world in relation to the complex global challenges of diversity, sustainability, and digitalisation.
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'.
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A sustainable environment
Making public space more sustainable is considered very important in this project. The Humanities Campus will become a pleasant place to spend time, with lots of greenery. Here, people can relax and find coolness on hot summer days.
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Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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Establishing State Responsibility in the Absence of Effective Government
On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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Research
Research at the Grotius Centre for International Legal Studies is primarily carried out under its Research Programme ‘Exploring the Frontiers of International Law’.
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Understanding the complexity of intelligence problems
The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.
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Constitutional and administrative law
Constitutional and administrative law covers a broad area of law. It provides the rules with which issues in society can be solved by government authorities.
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Spectacle and Surveillance: The Making and Unmaking of Collective Visual History
What is the iconography of propaganda specifically as it relates to the historical development of political ideologies in modern Egypt and how was/is this propaganda disseminated among creative fields such as cinema, art, monuments, architecture, and literature?
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Measurement of the average mass of proteins adsorbed to a nanoparticle by using a suspended microchannel resonator
SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.
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The Teacher’s Invisible Hand: A Meta-Analysis of the Relevance of Teacher–Student Relationship Quality for Peer Relationships and the Contribution
Social relationships of students are important. Especially for students with problem behavior. How can a teacher support students in their social relationships via their own interactions with students? A lot, as is shown by a meta-analyses of Hinke Endedijk. She assessed almost 300 studies about teacher-student…
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Research
Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.
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Beyond UN75: A Roadmap for Inclusive, Networked & Effective Global Governance
Drawing on insights from past and contemporary scholars and world leaders, the report explores the concepts of a new social contract, a new global deal, and networked and inclusive multilateralism introduced recently by Secretary-General António Guterres to help the United Nations better grapple with…
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Parameter optimization toward optimal microneedle-based dermal vaccination
Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.
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PAIR: The Journal
PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
Source: J Cheminform, Volume 7, Issue 1 (2015)
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Monitoring the penetration process of single microneedles with varying tip diameters
Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.
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Does the Election Winner–Loser Gap Extend to Subjective Health and Well-Being?
In this article, Honorata Mazepus, assistant professor at the Institute of Security and Global Affairs, and Dimiter Toshkov, associate professor at the Institute of Public Administration, discuss whether the winner–loser gap extends beyond the political domain to subjective health and well-being as…
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Standardising care of the dying: An ethnographic analysis of the Liverpool Care Pathway in England and the Netherlands
The article 'Standardising care of the dying: An ethnographic analysis of the Liverpool Care Pathway in England and the Netherlands' by Erica Borgstrom and Natashe Lemos Dekker is published in Sociology of Health & Illness.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Political Conversion to Islam Among the European Right
In this paper, Sibgatullina and Abbas aim to illuminate the complex connections between the European right-wing movements and Islam and discusses how the adoption of Muslim identity may function as a politically strategic opportunity for European conservative forces.
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Measuring science communication impact
What tools can be applied to measure the output, outcome and impact of science communication efficiently and effectively?
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Explaining the gender gap in COVID-19 vaccination attitudes
In this article, Dimiter Toshkov aims to explains the gender gap in COVID-19 vaccination attitudes.
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Modulation of Stratum Corneum Lipid Composition and Organization of Human Skin Equivalents by Specific Medium Supplements
Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…
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Privatisations and golden shares: Bridging the gap between the State and the market in the area of free movement of capital in the EU
On 3 September 2019, Ilektra Antonaki defended her thesis 'Privatisations and golden shares: Bridging the gap between the State and the market in the area of free movement of capital in the EU'. The doctoral research was supervised by Prof. S.C.G. Van den Bogaert.
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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Explaining Contestation: Votes in the Council of the European Union
The researchers examine the Council of the European Union's voting behaviour between 2010 and 2021 and the impact of different independent variables.
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Lipid to protein ratio plays an important role in the skin barrier function of atopic eczema patients
The barrier function of the skin is primarily provided by the stratum corneum (SC), the outermost layer of the skin. Skin barrier impairment is thought to be a primary factor in the pathogenesis of atopic eczema (AE).
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A renewed awareness: Reinvigorating preparedness research for crisis and disastermanagement
In this article Jeroen Wolbers and Sanneke Kuipers take a closer look at disaster preparedness to reinvigorate the academic debate.
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Politics, Culture and National Identities 1789-present
Politics, Culture and National Identities investigates a wide range of national political cultures in Europe and the Americas in the 19th and 20th centuries.
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Health and the social investment state
Recent years have seen a vibrant scholarship on health policy and politics. While much is now known about changes to health policies and institutions over time, this study finds that scholarship still lacks research on the linkages between health policies and health outcomes (Marmor & Wendt, 2012).…
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The field and the classroom
The field and the classroom invites ethnographers to engage with critical and engaged pedagogies. Breaking down the barriers between fieldsite and lecture hall, this research cluster aims to interrogate the structures and values that shape anthropological and sociological education today.
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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Quality Management in Archaeology
The project entails research by international comparison into the effects of commercialisation in heritage management on the academic relevance and quality of the results of work that is essentially applied research. The research is carried out by Prof. dr. W.J.H. Willems and dr. M.H. van den Dries…
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Women in the 1970s
The Dutch women’s movement began around 1967 with the discussion of the disadvantages that women faced in daily life. In 1968 the MVM (Man-Vrouw-Maatschappij) was born and played an important role as a public voice demanding female education programs and inclusion in the workforce.
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Why Leiden University
Do you aspire to a career in international law? Then consider the Regular LL.M. in Public International Law at Leiden University.