Plant Sciences' contribution to the Host-Microbe Interactions research theme is to dissect how microorganisms and microbiomes interact with the plant host and the insects on those plants, and how these insights may be harnessed to improve plant growth and health, by steering microbiome composition and…

Restoring a natural plant environment on exhausted agricultural lands and in nature areas is difficult. We can speed this up by steering the soils towards the desired situation. This is what Martijn Bezemer, newly appointed Professor of Ecology of Plant-Microbe-Insect interactions at Leiden University’s…

Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver

Nadia Soudzilovskaia (CML), Martijn Bezemer (IBL / NIOO) and Harrie van der Hagen (ecologist at Dunea) gave an interview to NPO1 Radio about the TERRA-Dunes project.

Current research at the Skin Barrier and Vaccination group.

Lecture

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1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?

It is mostly rainfall and soil acidity that determine which microbes survive in a particular habitat and which do not. This knowledge is important for maintaining biodiversity. Leiden environmentalists contributed to the research. Publication in Nature on 1 August.

There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.

This project is part of the Next Generation ImmunoDermatology (NGID) consortium, which focuses on the comprehensive phenotyping of six different immune-mediated inflammatory skin conditions. A common factor contributing to these diseases is a dysfunctional skin barrier. The skin barrier function is…

PhD defence

This projects investigates spatial relations between soils and other resources and the urban layout of a classic Maya center in Campeche, Mexico.

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

How are the epidermal lipid pathways involved in health and disease.

Promotor: E.F. Smets Co-promotor: J. Geml

Promotor: E.F. Smets, Co-promotor: J. Geml

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Key publications of the Skin Barrier and Vaccination group.

On 11 May 2016 a prestigious NWO Vidi grant (NWO's Innovation Research Incentives scheme) has been awarded to Nadia Soudzilovskaia for her research proposal entitled “Do mycorrhizal fungi mediate soil carbon fate?”, aimed to understand mycorrhizal impact on soil carbon sequestration.

How do nonmotile microbes leverage communal motility?

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

A starring role for PhD candidate Andreea Nadaban during the annual meeting of the European Epidermal Barrier Research Network. With her talk about the arrangement of lipid molecules in the upper layer of our skin, she won the award for Best Oral Presentation.

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

Bacteria and fungi on organic dairy farms are significantly different from those on conventional farms. That was discovered by postdoc researcher Sofia Gomes and her supervisors Nadia Soudzilovskaia and Peter van Bodegom in collaboration with the Louis Bolk Institute and Naturalis Biodiversity Centre.…

Host-Microbe Interactions is one of the four research themes of the Institute of Biology Leiden.

Pathogenic bacteria are increasingly resistant to today’s antibiotics. Professor Gilles van Wezel seeks new forms of antibiotics in good bacteria that live in the soil.

This project investigates the well-preserved agricultural terraces of the Inn valley and the evolution of resource use in the inner Alps.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.

The lipid matrix in the stratum corneum (SC), the upper layer of the skin, plays a critical role in the skin barrier. The matrix consists of ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs).

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

In this article, Friso Selten and Bram Klievink explore how public organisations strategically manage the adoption of AI.

Lecture

PhD defence

This 48-month project is to contribute to a solid, accessible, domestically owned knowledge base for people-centred interventions aimed at strengthening access to justice in Libya (A2JiL), and to disseminate such knowledge among stakeholders, enhancing awareness and the capabilities required to provide…

A memorable farewell symposium and a royal distinction: Professor Joke Bouwstra could not have completed her career at Leiden with more pleasure. On Friday, 14 June, she received a Royal Honor from Leiden Mayor Peter van der Velden, who appointed Bouwstra as a Knight in the Order of the Dutch Lion for…

Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?

Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs

PhD defence