Some species of proteins which can form liquid-like condensates, also exhibit growth into fibers (or fibrils). One particularly interesting set of such proteins are those that are associated with neurodegeneration in which the fiber growth may be related to the pathological fibrils observed in disea…

Mit Beiträgen von R.R. Newell, E.J. Brinkman und Corrie C. Bakels

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

This article describes the phenomenon of firearms violence and the importance of including non-lethal firearms violence in understanding this phenomenon.

The ethics of ghosts, spectres, and mediums in postcolonial literature

Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.

Müller, Braun & Fraussen examine the conditions under which commissioners appear in the news and which communication strategies they pursue.

This research sets out to answer the following questions:

How, when and why the EU legislates to facilitate the private enforcement of EU law before national courts.

On 1 October 2020, Arianne de Leeuw defended her thesis 'Scheiding van zeggenschap en belang in de familiesfeer'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. A.O. Lubbers.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

This article researches the public perception of terrorist attacks by measuring the importance the public assigns to attributes of terrorist attacks.

This monograph, written by dr. Dennie Oude Nijhuis and published by Cambridge University Press, discusses the postwar development of the welfare state.

Promotor: S.M. Verduyn Lunel

On 25 November 2020, Sara Arendse defended her thesis 'De uiterlijke verschijningsvorm in het strafrecht'. The doctoral research was supervised by prof. C.P.M. Cleiren and prof. J.M. ten Voorde.

Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…

Press freedom in Indonesia is still under pressure, despite the demise of Soeharto’s regime in 1998

The Board of Examiners consists of scientific staff members of the IBL, Naturalis Biodiversity Center and CML, who teach in the biology programmes. They are appointed by the Board of the Faculty of Science and act independently from the research institutes. The responsibilities of the board include…

Promotor: J. Zaanen

Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.

Parliaments in democratic systems serve as the people’s representatives, legislators and overseers of the executive. They have the power to define the framework in which the executive can act and must report about its action. For parliaments to fulfil their roles, though, they depend on access to information.…

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

The applications of studying the early development of insects range from agriculture to material science.

Development of a curricumlum for EACTP's certification for turnaround professionals.

How to related figures of savages to conceptions of history?

Abrupt Climate Change and Cultural Transformation

What motivates people to provide help to, or seek help from other groups? And what are the psychological consequences of receiving help from another group?

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

The present study explores the role of water in the ancient Roman city of Ostia.In antiquity, Ostia was situated at the intersection of the Tiber River and the Mediterranean Sea, and acted as one of the harbour cities of Rome for several centuries.This study investigates how water was acquired, used,…

Promotor: Prof.dr. M. Ubbink

The Netherlands Institute in Morocco (NIMAR) is a Leiden University institute. It is financed by the Ministry of Education, Culture and Science and the Ministry of Foreign Affairs.

This thesis describes the design, characterization and application of dextran based crosslinked network.

How are the epidermal lipid pathways involved in health and disease.

Great apes and the right to health

In his groundbreaking Imagined Communities, first published in 1983, Benedict Anderson argued that members of a community experience a

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Cultural biographies of persons, objects and 'natural' places in the Bronze Age of the Southern Netherlands, c. 2300-600 BC.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli

On 7 March 2019, Maria de Jong-de Kruijf defended her thesis 'Legitimiteit en rechtswaarborgen bij gesloten plaatsing van kinderen'. The doctoral research was supervised by Prof. mr. M.R. Bruning en Prof. mr. T. Liefaard.

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Musters

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Anna Scott is a Canadian pianist-researcher interested in using the early twentieth century recordings of the Brahms circle of pianists to question persistent gaps between the loci of knowledge, ethics, and act in both modern mainstream and historically-informed performances of Brahms’s late piano w…

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

This research note argues that the “lone wolf” typology should be fundamentally reconsidered.

The book addresses the question “How and why do people become involved in European homegrown jihadism?