The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

On the 12th of November, Xander Vertegaal successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Xander on this achievement!

Combined hormonal contraceptives (CHC) are associated with an increased risk of venous thromboembolism (VTE). In 2013, a review was published by the European Medicines Agency (EMA). In this review, the authors concluded that the risk of VTE varies by the type of progesterone in the CHC. Subsequently,…

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

The Centre for the Study of Political Parties and Representation (CSPPR) aims to serve as an interdisciplinary platform for scholars of Leiden University for research focusing on the historical and contemporary operation and functioning of political parties and political representation, with a particular…

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

What is the cost of visual complexity? This dissertation sets out to determine the effect of the complexity of word formation on the legibility of Arabic and the role that vocalization plays in reading.

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

On the 12th of December, Eleanor Dutton successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Eleanor on this achievement.

This thesis attempts to establish a dialogue between the modern and the medieval traditions in logic, by means of ‘translations’ of the medieval logical theories into the modern framework of symbolic logic, i.e. formalizations.

Chinese athletes must perform this Olympics. Anything less than a gold is being seen as athletes being unpatriotic by furious nationalists online. Florian Schneider, director of the Leiden Asia Centre, explains the situation on BBC News.

In recent years, online platforms have been utilized more and more to spread Chinese nationalist discourse. In an interview posted on The Diplomat, director of the Leiden Asia Centre Florian Schneider gives his thoughts on how the digital environment has changed the way Chinese activists work.

The Linked In profile of alumnus Arne Driessen describes him as a ‘serial entrepreneur’. After studying Japanese he ended up working for a translation agency, after which he founded his own online marketing company, which he later sold to enable him to do something different again: making offices more…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Diplomatic Studies (DIST) is a peer-reviewed book series that encourages original work on the theory and practice, processes and outcomes of diplomacy.

Leonard Blussé, emeritus Professor in the History of European and Asian relations, will receive the prestigious Japanese Academic Fukuoka Prize. Blussé receives the prize for creating a new academic field: 'The Maritime History of early modern East/Southeast Asia'. He will receive the Prize in September…

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

PhD defence

Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?

Annemarie Samuels and Andrew Littlejohn, Assistant Professors at the Leiden Institute of Cultural Anthropology and Development Sociology, have both been awarded a Leiden University Fund research grant. Samuels will use the grant to kickstart a multi-sited ethnographic study of care at the end of life.…

On 23 September, the Leiden alderman for the Management of Public Space was presented with a Ginkgo Biloba in the Blekerspark. This special 'Peace Tree' was grown from a seed from a tree that survived the atomic bomb that devastated Hiroshima. The Peace Tree is being temporarily housed in Leiden's Hortus…

Promotor: Prof.dr. G.P. van Wezel

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

The Organ Art of the first female German concert organist and Bremen Cathedral organist and

We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.

Markus Davidsen defended his thesis on 16 October 2014

The death of George Floyd has led to fierce protests against police violence in the United States and beyond. What effects are we seeing in our University community? We discussed the situation with Diversity Officer Aya Ezawa.