The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

The PhD Committee is a bottom-up initiative that aims to create an open, active, and fun environment for all PhD candidates at Leiden University’s Faculty of Archaeology.

How are the epidermal lipid pathways involved in health and disease.

In his groundbreaking Imagined Communities, first published in 1983, Benedict Anderson argued that members of a community experience a

Great apes and the right to health

Cultural biographies of persons, objects and 'natural' places in the Bronze Age of the Southern Netherlands, c. 2300-600 BC.

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

The aim of 'Intergroup helping' is to provide an overview of psychological research on intergroup helping, such as between countries or organisations, or in case of international crises. Co-editor Esther van Leeuwen has been an assistant professor at Leiden University in Social and Organisational psychology.…

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

A comparative study in the History of Modern Philosophy focused on the recourse to physiology on the part of two key figures, Spinoza and Nietzsche.

Some species of proteins which can form liquid-like condensates, also exhibit growth into fibers (or fibrils). One particularly interesting set of such proteins are those that are associated with neurodegeneration in which the fiber growth may be related to the pathological fibrils observed in disea…

Mit Beiträgen von R.R. Newell, E.J. Brinkman und Corrie C. Bakels

The Board of Examiners consists of scientific staff members of the IBL, Naturalis Biodiversity Center and CML, who teach in the biology programmes. They are appointed by the Board of the Faculty of Science and act independently from the research institutes. The responsibilities of the board include…

Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…

On 25 November 2020, Sara Arendse defended her thesis 'De uiterlijke verschijningsvorm in het strafrecht'. The doctoral research was supervised by prof. C.P.M. Cleiren and prof. J.M. ten Voorde.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

On 1 October 2020, Arianne de Leeuw defended her thesis 'Scheiding van zeggenschap en belang in de familiesfeer'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. A.O. Lubbers.

This article researches the public perception of terrorist attacks by measuring the importance the public assigns to attributes of terrorist attacks.

Within this project, PeptoMiktoStars were realized through an orthogonal protecting group strategy and should be investigated further regarding their potential as drug delivery systems in the field of drug delivery to inflamed areas in cancer, bacterial infections or autoimmune diseases.

Development of a curricumlum for EACTP's certification for turnaround professionals.

The applications of studying the early development of insects range from agriculture to material science.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Press freedom in Indonesia is still under pressure, despite the demise of Soeharto’s regime in 1998

How to related figures of savages to conceptions of history?

Promotor: J. Zaanen

The book addresses the question “How and why do people become involved in European homegrown jihadism?

Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

The present study explores the role of water in the ancient Roman city of Ostia.In antiquity, Ostia was situated at the intersection of the Tiber River and the Mediterranean Sea, and acted as one of the harbour cities of Rome for several centuries.This study investigates how water was acquired, used,…

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Musters

On 7 March 2019, Maria de Jong-de Kruijf defended her thesis 'Legitimiteit en rechtswaarborgen bij gesloten plaatsing van kinderen'. The doctoral research was supervised by Prof. mr. M.R. Bruning en Prof. mr. T. Liefaard.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli

Anna Scott is a Canadian pianist-researcher interested in using the early twentieth century recordings of the Brahms circle of pianists to question persistent gaps between the loci of knowledge, ethics, and act in both modern mainstream and historically-informed performances of Brahms’s late piano w…

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

This research note argues that the “lone wolf” typology should be fundamentally reconsidered.

This thesis describes the design, characterization and application of dextran based crosslinked network.

The Netherlands Institute in Morocco (NIMAR) is a Leiden University institute. It is financed by the Ministry of Education, Culture and Science and the Ministry of Foreign Affairs.

Promotor: Prof.dr. M. Ubbink

Promotor: T. H. Oosterkamp

Promotor: Prof.dr. J. Memelink

On 18 December 2019, Marianne Lochs defended her thesis 'Contempt of court'. The doctoral research was supervised by Prof. C.P.M. Cleiren and Prof. J.H. Crijns.

The philosopher and psychologist G.F. Stout was the teacher of Moore and Russell around 1894. This book shows that Stout's ideas have played a role in Moore and Russell's development from their early idealism towards analytic realism, where Stout's ideas often find their origin in early phenomenolog…

Port cities develop at the intersection of international trade and commerce and at the interface between sea and land. What does the future of port cities look like with urbanization, sea level rise, new migrant flows and the disappearance of old industries? This is addressed in the minor (Re)Imagining…

The Institute of Education and Child Studies aims to create a challenging academic environment in which students can flourish.

On 17 April, Evert-Jan Govaers defended the thesis 'Ministers of State. Unknown and desired; from stage to the wings?'.The doctoral research was supervised by Wim Voermans.

It is a tragic fact that mass atrocities have been, and are being, committed across the world. The international community, while condemning these acts, often stands idly by. This conundrum raises a host of empirical, legal, and normative questions regarding the role of public opinion in responding…