168 search results for “vries” in the Public website
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Medical Systems Biophysics and Bioengineering
The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.
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Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines
Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)
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Public leadership as a balancing act? How leaders’ context influences leadership
Public leadership received increasing attention, but we still do not understand how the context of public leaders affects leadership. This research project delves into public leaders’ perceptions of the leadership situations they find themselves in, which are characterised by multiplicity – one could…
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Non-take-up of social support and the implications for social policies
This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.
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Governance of Innovation Project Management: Necessary and Neglected
Promotores: B.R. Katzy, J. de Vries, Co-Promotor: L.P. Groenewegen
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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About us
The Faculty of Archaeology at Leiden is the leading academic institute for Archaeology in the Netherlands, and one of the largest in the world. The Faculty is an international front-runner, in the top ten of the QS World University Ranking, at subject level.
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Targeted Informed consent: empowering young participants in medical-scientific research
Promotor: J.M. van den Broek Co-promotor: M.C. de Vries
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Prof. dr. J.D. Speckmann prize
Annually the Institute of Cultural Anthropology and Development Sociology awards the Speckmann prize for the best Fieldwork NL report, as well as the most accomplished master’s thesis.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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Allosteric Modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…
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The Postal Imagination: Returning Mail in Contemporary Culture
How to understand the simultaneously dis- and reappearance of letters in contemporary culture, and how does this Neo-Epistolarity relate to media-technological change?
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Towards a comprehensive understanding of (facilitating) teacher professional development
What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.
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Book presentations
Now and then we organise book launches to present the latest publications, both academic and popular, in our broad field.
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Receptor Residence Time
Research question
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Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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‘First determine goals, then make healthcare choices’
What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made. This is what Martine de Vries, Professor of Normative Aspects of Medicine, advocated during her inaugural lecture on Friday, 2 November 2018.
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Key publications
Key publications of the Predictive Pharmacology group.
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
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Kraft Lab - Self-assembly in Biological and Soft Matter
Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.
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Our people
Some examples of AI-research done at Leiden.
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Research and design in secondary science education
Research and design are becoming more and more important in international science education. In The Netherlands, two recently introduced subjects focus on research and design activities in the classroom: O&O (research and design) and NLT (nature, life and technology). This research aims to look at what…
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Allosterism
The recognition that there may be more, so-called allosteric binding sites on a given receptor has also fueled our synthetic efforts. Over the last few years we have focused on many drug targets (adenosine A1, A2A and A3 receptors, the mGlu2 receptor and a classic ‘anti-target’, the hERG channel) to…
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Exhibition sculpture ‘Zie Justitia’ at Leiden Law School extended until January 2023
The art committee of Leiden Law School has extended the exhibition of the sculptures by the Leiden artist Koen de Vries in the C-wing of the KOG building until January 2023. On Thursday 8 December, the finissage of the exhibition will take place in the C-wing at 16.45 hours with drinks and light sna…
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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Policing Studies
The research group Intelligence and Security has been augmented with a team Policing Studies as part of the collaboration agreement with the Dutch National Police. This team is tasked with creating a more academic foundation for the current knowledge surrounding policing studies in the Netherlands,…
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What rights do donors have?
Collaboration is worthwhile. A joint LUMC and Leiden Law School project has received €142,500 from the Dutch Research Council (NWO). This grant will advance research into the law and ethics of regenerative medicine.
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Safety of journalists most important theme of 2022 Press Freedom Index
On 3 May, World Press Freedom Day was held and the Dutch 2022 'Persvrijheidsmonitor' was presented. The safety of journalists in 2022 was the most important theme in the area of press freedom in the Netherlands. Tarlach McGonagle, Professor of Medial Law & Information Society in Leiden, and Otto Volgenant,…
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Lipid signaling in brain diseases
Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].
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Alumni
Former PhD, Bachelor and Master students of the Van Exter Lab
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Previous SAILS Workshops
SAILS likes to occasionally organise workshops about topics that relate to our programme. On this page you can find more information about previous workshops.
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Three students of the Institute of Immigration Law publish blog post on the refugee crisis
Three MA students of the Institute of Immigration Law, Nick Perre, Myrthe De Vries and Hannah Richards have co-authored together with Mariana Gkliati, a blog deconstructing the notion of the ‘refugee crisis’ and connecting it with observations from a wider spectrum of socio-economic formations, which…
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‘It’s a real balancing act for doctors at gender clinics’
Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.
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Wijnhaven: where you can get to know the world
On 10 February Leiden University celebrated the official opening of Wijnhaven, the University's newest premises in The Hague. Everyone present emphasised the added value of a modern location in the heart of the city.
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Hall of Fame Leiden Law School staff 2023
Lots of employees celebrated special successes in 2023. Here’s a list of all those scholarships, awards and honours.
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Skilled students: this is how the Science Skills Team supports you as a teacher
Education is more than just knowledge transfer: students also develop numerous important skills. But which skills are addressed in which courses? And how can we help students train these skills? The Science Skills team is actively engaging with teachers to answer these questions for all courses. Want…
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Young transgender people are able to decide about puberty blockers
Young transgender people are able to decide together with their parents on a reversible intervention with puberty blockers. These are the results of a study by LUMC Curium and Amsterdam UMC of 74 young people undergoing treatment. Ninety percent of the young people studied proved able to make an informed…
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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A successful PhD Day 2024 at the Europa Institute
On 20 June 2024, the Europa Institute held its annual PhD Day at the Gravensteen Building. This event brought together PhD candidates in European law to present their research projects, share input from preliminary findings and engage in discussions with their peers and supervisors. The day was filled…
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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Freya Baetens delivers keynote presentation at Carmel Academic Centre
On 20 June, Freya Baetens delivered the keynote presentation at a workshop on
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Sophie Vériter Discussant at Annual Dahrendorf Lecture, Oxford University
On 29 April, doctoral researcher Sophie Vériter will join the annual Ralf Dahrendorf Memorial Lecture at St Antony’s College, Oxford University as a discussant.
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Ukraine candidate for EU membership? Armin Cuyvers on BNR
If it were up to Ursula von der Leyen, a positive opinion on Ukraine's application for membership would be forthcoming this Friday, 17 June.
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NWA grant for health law as part of NWA Cure4life
Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…
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Schouwburgstraat Community Garden
In September 2023, we started transforming a under-utilised outdoor space into a greener and more biodiverse garden in which all students and staff of the Schouwburgstraat can relax and enjoy.
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A healthy start for all
Many children have an unhealthy diet and do not get enough exercise. Sanne de Vries wants to help everyone get a healthy start in life.
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LLX roundtable on coronavirus relief fund NextGenerationEU
On Friday 21 May, the Europa Institute held an online roundtable on the European Union’s coronavirus relief fund NextGenerationEU. The roundtable was organised in the context of the Leiden Law Exchanges (LLX). Their aim is to facilitate an exchange of ideas on current legal issues between academics,…