This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?

In The Agency of Empire: Connections and Strategies in French Expansion (1686-1746) Elisabeth Heijmans places directors and their connections at the centre of the developments and operations of French overseas companies.

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

From ca. 1540 to 1600, thousands fled the war-stricken Southern Low Countries to the British Isles, Germany, and the Northern Low Countries. Research on this displacement crisis, central to the formation of the Netherlands and Belgium, reflects 21st-century debates on migration and language: language…

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

This project aims to provide evidence-based knowledge on the conditions for successful anti-corruption activism in Ukraine.

Proceedings of the 25th International Congress of Roman Frontier Studies 2

Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken

The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

Promotores: G. Persoon, R. Schefold

On 23 June 2020, Santy Kouwagam defended her PhD-thesis 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. The doctoral research was supervised by Prof. A.W. Bedner and Prof. C.E. von Benda-Beckmann.

What is effective viewing behavior for foreign language learners and how can teachers effectively train language learners to apply effective viewing strategies that will maximize their learning when viewing subtitled materials?

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

CML report 192

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

On February 20th, Gulnaz Sibgatullina succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Gulnaz on this great result.

In this article, Tom Buitelaar proposes a systematic framework for analyzing the impact of individual characteristics of peacekeeping leaders on the behaviour of field-level personnel in UN peacekeeping operations.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Is it possible to formulate a new conceptual foundation for attributing an evaluative role to historiography of science, without relinquishing the historiographic sensitivity of recent work in the discipline?

What tools can be applied to measure the output, outcome and impact of science communication efficiently and effectively?

The overall objective of ECS is to widen and strengthen the European Citizen Science community through capacity building and awareness raising activities such as the creation of a European Citizen Science Academy and the establishment of a network of 28 ECS Ambassadors.

How can we bridge the gap between experts and the general public?

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

Lecture, European Union Seminar

PathOS aims to contribute to a better understanding and measurement of Open Science impacts and their causal mechanisms. This is pivotal in order to develop effective OS policy in the EU (European Union). It will do so by collecting concrete evidence of OS effects, by studying the pathways of OS practices,…

Corporate R&D organizations and their relation to academic laboratories.

The mission of the Plant Science research programme is to contribute to the sustainable production of high quality crops, flowers and high-value bio-based products. This is realised by generating fundamental knowledge of basic biological processes related to development of plants and their interaction…

The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.

In theory, states can gain security by acquiring internal arms or external allies. Yet the empirical literature offers mixed findings: some studies find arms and allies to be substitutes, while others find them to be complements. Political scientists Matthew Digiuseppe (Leiden University) and Paul Poast…

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

We are happy to welcome you to spend a semester or year studying with us at the Faculty of Science. Find information on your course schedules, enrolment and more on these pages.

The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…

There are eight institutes at the Faculty of Mathematics and Natural Sciences:

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

The Faculty of Science

This NWO-funded research programme focuses on the assumptions and methodology of the writing of history of science. History of science is in many respects a flourishing discipline: it currently yields an impressive volume of studies. Systematic reflection about the ways in which history of science may…

Lecture, Tuesday Talks: Science Insights

This research project addresses an unexplored dimension of historical conflict resolution: the dynamics of strategic choices made by traders engaged in foreign trade in the city of Danzig (Gdansk) c. 1450-1580, a Hanseatic city under the Polish Crown.

The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.