1,141 search results for “have screen” in the Public website
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Crystal Cave
X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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Film Screening: Foragers
Lecture, Teach-In Series on Palestine and Israel
- Facilities
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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation
Source: PLoS ONE, Volume 10, Issue 3 (2015)
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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General Lab Facilities
Shared, general-purpose labs.
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Research
An overview of the research at the Cancer Dug Target Discovery group.
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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From the birth of galaxies to an IMAX movie on the big screen. Leiden partnership wins award from the Royal Astronomical Society
Simulation project EAGLE has won the 2022 Group Achievement Award of the Royal Astronomical Society. EAGLE is a large collection of simulations about the formation of galaxies. The largest simulation contains as many as 6.8 billion particles and took months to calculate on the world's fastest superc…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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Serkan Aslan
Science
s.aslan@lacdr.leidenuniv.nl | +31 71 527 5919
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Zebrafish Delivery
Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Barrier properties of an N/TERT based human skin equivalent
Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Career prospects
The master's specialisation in Visual Ethnography enables you to combine technical mastery of audiovisual production with ethnographic research skills. Your experience ranges from project design to field studies, to scholarly output.
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Systems pharmacology-based translational drug pharmacokinetics
High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.
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Screening in low resource settings
PhD defence
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Student projects
Are you looking for a research project? We have projects available for motivated 6–9-month internship students with particular interest in organic/polymer synthesis, formulation development, gene delivery, protein delivery, and the preliminairy in vitro screening of drug delivery platforms. Students…
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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VR Tour The Hague
Curious to know how studying in The Hague looks like? Take our VR tour through The Hague!
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'Oqlanmagan – The Unexonerated': Film Screening and Discussion
Debate, Film Screening and Discussion
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Molecular mechanisms of adverse outcome and translational biomarkers
Adverse drug reactions (ADRs) remain one of the major reasons for patient mortality and (early) drug withdrawal. Currently, different in vivo and in vitro models are used to assess the toxic potential of drugs in the pre-clinical phase. Unfortunately, the predictive value of this model does not fit…
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The Living Lab, Schouwburgstraat
A large, 64+ person space with multiple working zones in the Schouwburgstraat building, Den Haag. Tables fold and wheel, and chairs are also on wheels. There are multiple movable whiteboards which allow group working in various sizes. Windows and tables are additional writing surfaces. There is also…
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.
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Identification of novel targets in prostate cancer progression
Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Dutch Extract Library
We like to welcome you kindly to the Dutch Extract Library.
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The path to individualised breast cancer screening
PhD defence
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CEES/ReCNTR Screening: Morality is Good
Arts and culture
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Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Screening the CITY: Optimizing population-based cancer screening in the Netherlands from a primary care perspective
PhD defence
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Glucocorticoids in zebrafish
A novel in vivo model system for studies on glucocorticoid resistance
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Re-envisioning nature: the representation of post-nuclear landscapes in contemporary art and culture
How does contemporary art and culture represent nuclear contamination in post-nuclear landscapes?