Examining the therapeutic potential of new semisynthetic lipopeptide antibiotics

What are the various forms of inter-organizational collaboration in the public safety sector? How are different forms of inter-organizational collaborative arrangements related? What is the relationship between inter-organizational collaboration and innovation in the public safety sector?

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

On 29 June May 2022 Yujing Tan successfully defended a doctoral thesis and graduated.

Promotor: E.F. Smets Co-promotor: J. Geml

Higher design and engineering educators have different views on what a new or renewed curriculum should entail, content-wise as well as pedagogically. This research aims to describe how these ‘curriculum perspective perceptions’ influence working definitions, end goal formulation, and the scope of results…

The focus of health care is rapidly changing. The need for maximum gains with minimal input requires tailored health care strategies and an ever more explicit evaluation of health benefits for the patient.

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

The research reported in this thesis is concerned with the knowledge development of a small sample of experienced science teachers in the context of a broad innovation in Dutch secondary education, including the introduction of a new syllabus on Public Understanding of Science.

Kohei Suzuki, assistant professor at Leiden University, together with Victor Lapuente, examined how male and female public managers show attitudinal differences toward innovation in the public sector.

Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt

The STRINGS project is mapping development pathways for science, technology and innovation that best address the UN Sustainable Development Goals. A consortium of seven universities led by Tommaso Ciarli at SPRU at the University of Sussex and the UNDP (United Nations Development Programme) have worked…

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

How can legal education in Indonesia become more relevant for graduates who will work in contexts of legal pluralism, aiming for social justice and providing legal services that common citizens need?

If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.

A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

To what extent are university teachers' individual learning paths influenced by their teaching experience, motivation, and conceptions of teaching and learning through educational technology?

The aim of this research project was to increase understanding of which collaborative learning approaches already exist in conservatoire education, and how implementation of collaborative learning could be supported.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Bernard Bernards examines constraints on innovation by focusing on cognitive uncertainty as a personal state that may affect innovative work behavior.

The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…

Responsible Research and Innovation (RRI) implies that societal actors (researchers, citizens, policy makers, business, third sector organisations, etc.) work together during the whole research and innovation process in order to better align both the process and its outcomes with the values, needs and…

In this book, Sarah Giest, Assistant Professor at the Institute of Public Administration, provides insight into the collaborative and absorptive capacities needed to provide public support to local innovation through cluster organizations.

The main aim of the project is to collect and update on a regular basis bibliometric and patent indicators that can be used to underpin and inform analyses pursued at the European Commission (EC) to assess European and national scientific and technological performance.

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…

The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…

In this research note, Van der Does & Kantorowicz aruge that citizens that tend to experience political exclusion are often more supportive of direct and participatory forms of decision-making.

How do teachers’ knowledge, practices, perceptions, job satisfaction and workload in secondary education develop during a school innovation in the context of differentiated student development?

Dr. Joris Larik, Assistant Professor of Comparative, EU and International Law at LUC The Hague, has co-authored a report entitled 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.

Political scientist Corinna Jentzsch (Leiden University) about the organisation of rebel and government auxiliaries in the civil war in Mozambique (1976–1992).

To what end and how does Plautus constantly underline the Helleni(sti)c provenance of his art? How does this aspect relate the author’s originality?

Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability: deepening, broadening and leaping forward the LCA methodology.

Carina van den Hoven defended her thesis on 16 February 2017.

In recent years, the question why citizens (do not) support democratic innovations has attracted increasing academic attention. In this research note, Van Der Does & Kantorowicz for the first time empirically verify what drives citizens’ instrumental considerations in their evaluation of a DI.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

(1) What are the institutional factors that influence AI adoption and implementation? and (2) How does AI reshape the exercise of administrative discretion within public organisations, and how do adoption and implementation choices moderate these effects?

PhD defence

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Developing robust and comprehensive analytical methods to size and quantify subvisible particles in biopharmaceutical products.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

This project aims to further understand the molecular details related to the biosynthesis and function of Galf containing glycoconjugates in fungal Aspergillus spp.

This PhD subproject concentrates on 16th-century ichthyology and takes Gessner’s Historia piscium (1558) (further HP) as its point of departure and focus.