4,015 search results for “discovery of the year” in the Public website
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Discovery of a unique silver bowl from the Early Middle Ages
On an excavation site in Oegstgeest Leiden University archaeologists discovered a very rare silver bowl from the first half of the seventh century. The bowl is decorated with gold-plated representations of animals and plants and inlaid with semi-precious stones. The discovery suggests the existence…
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Discoverer of the Year, Best Dissertation and Education prize 2015
During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.
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Scientific computing for Drug Discovery in Python and/or R
Data analysis with Python and R are rapidly becoming essential skills for modern scientists. Therefore, we are offering courses to develop your scientific computing skills. Those courses are optional for LACDR PhD candidates.
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LED3 Lecture: Microbial Natural Products in Drug Discovery
Lecture
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Luuk Esser in the media on discovery of 39 bodies in England
The British police discovered 39 bodies in the back of a lorry earlier this month. The refrigeration unit in which the bodies were found had entered the United Kingdom via Belgium.
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Discovery of unknown translation of René Descartes’ 'L’homme' in Leiden Bibliotheca Thysiana
From time to time, manuscripts that have remained hidden for centuries turn up in library collections and archives. In the archives of the 17th-century Bibliotheca Thysiana at the Rapenburg in Leiden, kept in the Leiden University Library, Rotterdam researcher Erik-Jan Bos discovered a hitherto unknown…
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‘Discoverer of the Year’, best dissertation and Education Award 2014
At the New Year’s reception of the Faculty of Science on 6 January, it was announced that Annelien Zweemer, Leiden Academic Centre for Drug Research, has been awarded the ‘Discoverer of the Year 2014’ prize. Matteo Brogi, Leiden Observatory, wrote the best dissertation in 2014 and Dennis Claessen, Institute…
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Knowledge Discovery and Data Mining from patient experience repositories
This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.
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First discovery of methanol in a warm planet-forming disk
An international team of researchers led by Alice Booth (Leiden University, the Netherlands) have discovered methanol in the warm part of a planet-forming disk. The methanol cannot have been produced there and must have originated in the cold gas clouds from which the star and the disk formed. Thus,…
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Causal Discovery from High-Dimensional Data in the Large-Sample Limit
Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets
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Evani Lachmansingh
Science
e.t.lachmansingh@liacs.leidenuniv.nl | +31 71 527 2727
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Systems microscopy-based drug target discovery in pathogen-meidated inflammatory respons signalling
Establishing human induced pluripotent stem cell (iPSC) CRISPR-Cas9-based fluorescent reporter cell lines for NF-kB signalling. We will use this to enable studying the dynamic activation and downstream signalling of Toll-like receptor and cytokine signalling in iPSC-derived differentiated cells in a…
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Mortality and HyperImage: Visual analytics techniques for biomarker discovery in massive 3D-omics datasets
Over the past decade, several novel types of spatially resolved
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resources for Iberian empires: ecology and globalization in the age of discovery
An interdisciplinary and innovative research group combining History, underwater archaeology, GIS and wood provenancing methods.
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In pictures: the Night of Discoveries
Over 4,000 visitors came to the seventh edition of the Night of Discoveries, a festival of knowledge and culture, on Saturday 21 September. On this the last summer evening of the year, the festival-goers were treated to over 170 acts on the theme of light and dark, making it a vibrant, busy, educational…
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Alexander van Oudenhoven Discoverer of the year 2016
Environmental scientist Alexander van Oudenhoven has been chosen as Discoverer of the year of the Faculty of Science. Vice Rector Magnificus Hester Bijl announced this during the faculty’s New Year’s Reception on 10 January. Biologist Changsheng Wu won the prize for best dissertation of 2016. Computer…
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken
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data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Knowledge discovery from patient forums: gaining novel medical insights from patient experiences
Patients share valuable advice and experiences with their peers in online patient discussion groups.
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Vote for Discoverer of the Year
Who will be our Discoverer of the year 2017? Which one of these brilliant researchers deserves this prize for their efforts according to you? As of now, you can cast your vote.
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Vote for Discoverer of the Year
Scott Waitukaitus has been nominated by LION to be Discoverer of the Year 2017. Cast your vote now!
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Dennis Claessen: “Teacher of the Year 2014”
Students of the Faculty of Science have chosen Dennis Claessen (IBL) as the best teacher of last year.
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi
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Discoverer of the Year 2014: Annelien Zweemer
Former PhD student Annelien Zweemer was granted the C.J. Kok Award 2014, also known as “Discoverer of the Year”. A festive ceremony took place at the Faculty’s New Year’s reception on January 6, 2015.
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Kinetics for Drug Discovery: a Case for the Adenosine A3 receptor
Supervisor: Lizi Xia
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PROTEOMINING: a novel proteomics-based pipeline for drug and enzyme discovery in filamentous actinomycetes
Can a new proteomics workflow be developed to link genes and gene clusters to bioactive molecules, identify novel compounds and enhance the production in the Streptomyces lividans enzyme?
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Vote for Discoverer of the Year 2017
Suzan Verberne is nominated by the Leiden Institute of Advanced Computer Science (LIACS) to be granted the C.J. Kok Public Award, also known as the award for the ‘Discoverer of the Year’.
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Hans Aerts
Science
j.m.f.g.aerts@lic.leidenuniv.nl | +31 71 527 4771
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Vote for the Discoverer of the year 2018
Which brilliant scientist will be our Discoverer of the year 2018? Will it be a physicist, biologist, drug discoverer or an astronomer? Or an environmental scientist, a mathematician, chemist or computer scientist? As of now, you can cast your vote.
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Impressions 2016 The year in photos
What went on in 2016 at our University? What are we proud of? You can view the answers in our new photo brochure. Our new brochure 'About us' is available as well, with the most recent facts and figures. Both brochures are available in English.
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Our Talents and Discoveries 2016
Christmas is coming, which means that 'Our Talents and Discoveries 2016' has been distributed. This also means that it is time to vote for the 'Discoverer of the year 2016'. Each of the eight institutes nominated one researcher that excelled in the past year. Who is your favourite?
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Arianna Pranger lecturer of the year 2019-2020
‘One lecturer stood out in particular,’ said Dirk van Vugt, Chair of the Leiden University Student Platform (LUS), at the opening of the academic year. ‘Despite the hurdles of remote teaching, she managed to inspire her students with the aid of knowledge clips, challenges and topical lectures about…
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Alireza Mashaghi Tabari is Discoverer of the Year 2017
With a large majority of votes, drug researcher Alireza Mashaghi Tabari was chosen Discoverer of the Year 2017 of the Faculty of Science. This was announced by Rector Carel Stolker during the faculty’s New Year's reception on 9 January. Computer scientist Kristian Rietveld became Teacher of the Year…
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Gerard van Westen 2013 Discoverer of the Year
Former PhD student Gerard van Westen was granted the C.J. Kok Award also known as “Discoverer of the Year”. A festive ceremony took place at the Faculty’s New Year’s reception on January 7, 2014.
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Daniela Kraft wins Biophysical Journal Paper of the Year Award
The editors of Biophysical Journal have selected a publication from Daniela Kraft’s group as the Paper of the Year 2017. The award recognizes an outstanding contribution by a young investigator.
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Leiden academics nominated for Person of the Year
Leiden academics Remco Breuker and Auke-Florian Hiemstra stand to win the title of Person of the Year.
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Computer scientist Frank Takes Teacher of the Year
Students of the Science Faculty of Leiden University have chosen Frank Takes, researcher and teacher at the Leiden Institute of Advanced Computer Science, to be the Teacher of the Year. Impressively enough, Takes also became the runner up Discoverer of the Year.
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Paul Adriaanse nominee for ‘MC Lawyer of the year’
Paul Adriaanse, together with eight other candidates, has been nominated in the administration law category for the title ‘Magna Charta Lawyer of the year’. The public will vote to decide the winner
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Auke-Florian Hiemstra named Person of the Year
Auke-Florian Hiemstra is the Leidsch Dagblad Person of the Year 2022.
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Discovery of selective diacylglycerol lipase β inhibitors
PhD defence
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
PhD defence
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Discoverer of the Year bridges science and medicine
Fascinated by science since high school, Alireza Mashaghi Tabari is driven to explore new ways of thinking in medicine. With a strong academic network, he educates students and gives public lectures. For his research at LACDR, he won the C.J. Kok Public Award 2018, making him the Faculty of Science's…