Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

Leiden University has awarded its prestigious University Medal to Emeritus Professor Lex van der Eb. As a pioneer in genetics and molecular biology, he received this honour for his services to science and his key role in the development of the Leiden Bio Science Park (LBSP).

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

Discover budding creators, artists and researchers at the Night of Discoveries art and knowledge festival. And many researchers from Leiden University are taking part.

Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.

It was the Night of Discoveries on Saturday 16 September: a summer encounter between art and science. Leiden researchers from various disciplines inspired the public with their quest to understand our world.

This week, we had the LACDR PhD Introductory course on Drug. This is always a great opportunity for starting PhD candidates to get to know LACDR, CHDR, the Clinical Pharmacology department of LUMC and the embedding of the institute in the BioSciencepark as a whole.

Recently, we had the LACDR PhD Introductory course on Drug Research for starting PhD candidates. It was great to have this live event live in castle Oud Poelgeest, after two years of restrictions.

Lecture, Tuesday Talks: Science Insights

At the end of February, we had the PhD Introductory Course on Drug Research for starting PhD candidates from LACDR. This 3-days event took place at Castle Oud Poelgeest, a great location to be completely out of the work environment. We welcomed 30 PhD candidates, with whom we had an inspiring and…

Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

The ‘Discovery of the Entrepreneurial Ecosystem of EUniWell’s Consortium’s Members’ project has received a EUniWell seed grant. Sjoerd Louwaars, the representative from Leiden University, talks about the project and the first results.

Due to the corona pandemic and the uncertainty of the circumstances end of January 2022, is decided to postpone the LACDR PhD introductory course.

The PhD introductory course will take place on 30 May, 31 May and 1 June 2022 in castle Oud Poelgeest. We are very happy that it will be a live event (as it stands now).

PhD defence

This study is important because it seeks to uncover whether clinicians' communication influences neurobiological and physiological outcomes for patients.

Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…

Polypeptide Therapeutic Solutions (PTS), a leader in the design, development and custom manufacturing of polyamino-acid based delivery systems for therapeutic drugs and the Leiden Academic Centre for Drug Research (LACDR) today announced a research collaboration to develop advanced drug delivery systems…

eLaw - Center for Law and Digital Technologies, is well represented at a number of activities in Leiden this week concerning Technology and Society!

Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…

When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.

Come to the Night of Discoveries art and science festival on 16 September. Various researchers from the university are speaking at the festival.

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

One of our PhD candidates at the LACDR, Joey Zuijdervelt, recently achieved recognition by winning the first prize in the ‘Schild-De Groen Onderzoeksprijzen’ for cancer research. His award-winning master’s thesis explored glioblastoma multiforme through an innovative orthotopic zebrafish xenograft model,…

For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.

Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years

Drug use during pregnancy seems like a choice without any consequences. However, the Dutch Public Prosecution Service (OM) has decided to prosecute a mother for using alcohol and drugs during her pregnancy. Mariëlle Bruning, Professor of Child Law, tells current affairs programme ‘Nieuwsuur’ that she…

In a recent article published on PLOS, Drs. Briana Pobiner and Ryan McRae of the Smithsonian Institution National Museum of Natural History discuss the top 13 discoveries in human evolution in 2023.

If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…

During the LACDR Fall Symposium, Daan Jiskoot received the annual Suzanne Hovinga Award for the best master thesis. Daan performed his Research Project 2 at the University of California, Irvine at the Prof. David Mobley lab, supported by LACDR supervisor Willem Jespers. The in silico determination of…

Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.

From time to time, manuscripts that have remained hidden for centuries turn up in library collections and archives. In the archives of the 17th-century Bibliotheca Thysiana at the Rapenburg in Leiden, kept in the Leiden University Library, Rotterdam researcher Erik-Jan Bos discovered a hitherto unknown…

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

Conference

In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…