A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

The research connected to this topic is related to Work and health.

Promotor: Prof.dr. J.P. Abrahams

Assistant Professor at the Metabolomics group, LUMC, The Nederlands

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.

Retrospection over the last 40 years the most important changes in care and research, where transparency accountability and guidelines became leading. On Huntington’s disease and cerebrovascular disorders the most important changes are illustrated.

The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.

Atopic eczema is a skin disease with increasing incidence currently affecting 25% of the paediatric population. In atopic eczema the skin barrier function is reduced. This barrier is formed by the outermost layer of the skin called the stratum corneum (SC). The SC consists of terminally differentiated…

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

.

The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.

The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…

Those who look ahead can see we build the future together.

PhD defence

The ‘Contagious!’ exhibition was set to open at Rijksmuseum Boerhaave in April but had to be postponed because of the corona crisis. The museum hasn’t been twiddling its thumbs in the meantime. The exhibition will now open on 16 July, and the corona crisis has a major role.

Professor of Developmental Biology Christine Mummery and chemist Dr Dennis Hetterscheid have each been awarded an ERC Proof of Concept grant. These grants are to explore the societal potential of ideas generated in previous ERC-funded projects.

How can we organise society so as to keep our planet habitable for us and for all other life forms around us? To answer this question, Leiden researchers collaborate across disciplines, from biology to data science, and from environmental economy to archaeology.

A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.

Scientists in Leiden are looking for signals in blood samples to predict whether patients will develop serious COVID-19 symptoms or not. Based on that knowledge, they will be able to propose targeted therapies to prevent serious symptoms. They hope to come up with the first results within the week.

Our vision of stress is starting to change fundamentally. We can suffer stress without even being aware of it, while sleeping as wall as during the day. Professor of Psychology Jos Brosschot will discuss this phenomenon in his inaugural lecture on 2 December.

PhD defence

During the 7th annual meeting of the Association for Researchers in Psychology and Health (ARPH) Sylvia van Beugen, from the Health, Medical and Neuropsychology unit, was awarded with the ’Best PhD Thesis Award’ for her dissertation ‘Psychodermatology 2.0: Towards improved assessment and effective digital…

Lecture, LACG Meetings

Learn all about the writing systems used in the famous wall poems of the city of Leiden.

Research facilities within reach of LIBC members:

Researchers, policymakers and funders have to take more account of the effect of sex and gender in scientific research. This is the view presented in an advice paper published by LERU, the League of European Research Universities. The lead author is Vice-Rector Simone Buitendijk.

Courses, business premises for startups or help applying for patents: there are many ways the university can help students or researchers with their businesses.

Annick Dezitter from Belgium celebrates 3 October with heart and soul: she has become a fanatical Leidener. Her portrait is part of Leiden meets Europe: an exhibition of 28 portraits of EU citizens in Leiden. City photographer and third-year Cultural Anthropology student Wilke Geurds explains.

A child who receives fewer nutrients in the womb than their identical twin brother or sister is more likely to have developmental problems later in life. This is what researchers from the Leiden University Medical Center (LUMC) write in The Lancet Child & Adolescent Health. This study shows that unfavourable…

World War II is never over for those who have lived through it. This is the conclusion of Cleveringa Professor Carol Gluck and her students after reading The Assault (De Aanslag) by Harry Mulisch. The book played a central role in Gluck’s honours course.

Professor David Fontijn is fascinated by the question why people destroy objects that are dear to them. It is a phenomenon that you find everywhere in the world, gaining particular strength in the European Bronze Age. Fontijn wrote a book on this ‘economy of destruction’, published by Routledge.

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

Prof. Andrea Evers is a health psychologist who studies the role of behavioural factors in health and disease. As a Medical Delta Professor, she is now affiliated with Leiden University, TU Delft and Erasmus University. In that position, she conducts research at the intersection of various disciplines.…

Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.

PhD defence

Lecture, Lecture part of a series

Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

Visitors to Leiden's City Hall and the University Library can visit the 444 Years of Leiden University exhibition from 25 January.

Your time at Leiden is about more than just studying. It is being a part of a lively and diverse student community. Living in beautiful and historic Leiden. And enjoying the rich cultural life of Holland, where you are right in the heart of Europe.

Leiden Law School at the heart of society

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Lecture

PhD defence

Psycho-physiological reactions to stress.

On December 5th, Matthias Pache succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Matthias on this great result.