2,630 search results for “media drug violence” in the Public website
-
Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
-
Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
-
About the programme
Drug Discovery and Safety consists of 120 European Credit Transfer System (EC) points.
-
Organisation
The Leiden Academic Centre for Drug Research (LACDR) is responsible for the research and education in Bio-Pharmaceutical Sciences carried out at Leiden University.
-
The publication of Domestic Homicide; a much-needed synthesis of the literature on domestic homicide.
By Marieke Liem and Frans Koenraadt. Domestic homicide constitutes an extreme type of interpersonal violence. This book offers a much-needed synthesis of the literature on domestic homicide, covering its history; the theories supporting it; its various forms such as filicide, intimate partner homicide,…
-
Student projects
Are you looking for a research project?
-
Art of Captivity / Arte del Cautiverio
Art of Captivity / Arte del Cautiverio tells a compelling story about Central America's drug war through a series of rich photographs. The book, which is entirely bilingual in English and Spanish, focuses on Guatemala, which has become the primary point of transit for cocaine produced in the Andes and…
-
Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
-
European Lead Factory
The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.
-
Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
-
Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
-
Strategy
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.
-
Career prospects
After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Life Sciences.
-
Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
-
Prediction of human (CNS) target site concentrations in health and disease
Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…
-
Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
-
Violence Visible and Invisible: On Political Violence and Forms of Aesthetic Resistance to its Erasure and Distortion. One day symposium
Conference
-
Clinton won, but the horserace continues
Let’s get this out of the way: Hillary Clinton won the 26 September 2016 presidential candidates television debate. Handily.
-
Popular Music in Southeast Asia
From the 1920s on, popular music in Southeast Asia was a mass-audience phenomenon that drew new connections between indigenous musical styles and contemporary genres from elsewhere to create new, hybrid forms. This book presents a cultural history of modern Southeast Asia from the vantage point of popular…
-
Mathematical modelling of adverse outcome pathways
In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.
-
Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
-
More effective blocking of CCR2 receptor
The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…
-
Novel Chemical Modalities
The Novel chemical modalities research group is headed by Assistant Professor Sebastian Pomplun. Sebastian started at the division of Medicinal Chemistry within the LACDR in September 2021. His lab develops technologies for the discovery of novel chemical modalities that can address challenging drug…
-
The year of the FGGA in 12 Facebook events and 12 Instagram highlights
Underneath you will find the 12 most important Facebook events that took place at the Faculty of Governance and Global Affairs in the past year, and an overview of our Instagram highlights of 2018.
-
In the media: Rector Carel Stolker on the new academic year
How is Leiden University doing in these times of corona, and what kind of new academic year can we expect? Rector Carel Stolker was interviewed by Dutch broadcasting companies Omroep West, Sleutelstad FM and JortCall.
-
Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
-
A much-needed new class of antibiotics
Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…
-
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
-
Single cell technologies for mechanobiology and mechanopharmacology
Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…
-
Systems pharmacology of human neuroendocrine disease entities
An important hormone excreting gland in the human body is the pituitary
-
Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange
-
BioTherapeutics (MSc)
The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…
-
Interdisciplinary research and teaching at Leiden University
Many of the challenges of our time are too complex to be resolved within the confines of a single discipline. Leiden University is a broad-based university where an incredible number of research fields converge. That makes us the ideal breeding ground for, and practitioners of, interdisciplinary research…
-
Phenomix Field Lab offers promising healthcare solutions
In the Phenomix Medical Delta Field Lab, which was officially opened on Thursday 9 July, scientists, healthcare institutions and businesses work together to develop innovative applications in the field of metabolomics. This research field makes it possible to determine which drugs will be effective…
-
In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
-
Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
-
Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
-
From Data to insight
Social science research helps us understand human behaviour and social structures. These are determined by various factors, which makes the research complex and increases the likelihood of drawing the wrong conclusions. The choice of research method and analysis is therefore extremely important. It…
-
Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
-
Hit Discovery
The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.
-
Does migration lead to more political and ideological related crime?
No evidence found that increasing migration leads to an increase in politically and ideologically motivated criminality. Migration flows have, however resulted in increased polarisation in the Netherlands.
-
New techniques for tuberculosis treatment
About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.
-
Systems Biomedicine and Pharmacology (MSc)
The two-years master’s specialisation System Biomedicine and Pharmacology at Leiden university focuses on predicting drug response with computational modelling, developing individualised therapies, and developing innovative analytical tools for personalised health strategies.
-
Contact
Division contact information & address
-
Defeat by popular demand: public support and counterterrorism in three western democracies, 1963-1998
Acquiring and maintaining public support is frequently cited as an important requirement for governments fighting non-state actors. But how exactly can public support influence the course of counterterrorism campaigns and thereby contribute to an escalation or de-escalation of violence?
-
Conrad's Shadow Catastrophe, Mimesis, Theory
Western thought has often dismissed shadows as fictional, but what if fictions reveal original truths?
-
About the programme
In the Master's programme Crisis and Security Management, specialisation Governance of radicalism, extremism and terrorism we focus on the academic body of knowledge on different form of protests, contention, resistance and violence. We explore and explain the emergence of radical and extremist move…
-
The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
-
Dosing considerations for preterm neonates: from pharmacometrics to clinical practice
Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.
-
Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman