2,760 search results for “science molecular” in the Public website
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Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Unlocking the chemistry of the heavens
How are the building blocks of life formed?
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Skin Lipids: Localization of Ceramide and Fatty Acid in the Unit Cell of the Long Periodicity Phase
The lipid matrix of the skin's stratum corneum plays a key role in the barrier function, which protects the body from desiccation. The lipids that make up this matrix consist of ceramides, cholesterol, and free fatty acids, and can form two coexisting crystalline lamellar phases: the long periodicity…
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Microbial Induction of Plant Resilience to Drought Stress (MicroRes)
What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?
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Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein
Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)
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In shape for photoregulation
How does the photoregulation mechanism work in detail?
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Data science and sports: a winning combination
Athletes always strive for the top. How can data scientists assist them in improving their performance? During the seminar Data Science and Sports, the possibilities and challenges of collaboration between these two worlds were discussed.
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Microplastics in artery plaque linked with higher risk of heart attack, stroke and death
You can't see them with the naked eye, but they are highly likely to pose a threat to our health: microplastics. These tiny plastic particles are present everywhere in the environment, including within our bodies. On science platform The Conversation molecular biologist Meiru Wang offers valuable insights…
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Social Science Matters: Climate change
Climate change is a hot topic and constantly in the news. Thousands of Dutch high school students protested at the Malieveld in The Hague. News website Nu.nl has barred climate change deniers from their comments section to prevent ‘fake news’. How does climate change impact the research community, and…
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Data Science certificates awarded to employees of Ministry IenW
On Monday, June 24th, 24 employees of the Ministry of Infrastructure and Water Management (IenW) received their certificates for completing Data Science courses, offered by the Leiden Centre of Data Science.
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BRASILIAE. Indigenous Knowledge in the Making of Science: Historia Naturalis Brasiliae (1648).
Investigating the intercultural connections that shaped practices of knowledge production in colonial Dutch Brazil.
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Towards in-cell structural study of light-harvesting complexes : an investigation with MAS-NMR
Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
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Orchid mycorrhizal interactions: evolutionary trajectories and ecological variations
The mycorrhizal symbiosis is among the most widespread species interactions on Earth. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Fast Oxygen Reduction Catalyzed by a Copper(II) Tris(2‐pyridylmethyl)amine Complex through a Stepwise Mechanism
The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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Electrocatalysis for sustainable energy
Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…
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Bridging the gap between physics and chemistry in early stages of star formation
A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Towards Optical Detection of a Single Electron
Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.
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Expertise
The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.
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Protoplanetary disk anatomy: examining the structure and chemistry of planetary birthplaces with simple molecules
This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.
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In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids
This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.
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Unveiling protostellar disk formation around low-mass stars
Promotor: Prof.dr. E.F. van Dishoeck, Co-promotor: S. Bruderer
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Single-molecule fluorescence in sequence space
The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…
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PhD candidate in the field of biochemistry
Science, Leiden Institute of Chemistry (LIC)
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Science Letter
Science Letter
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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Sense Jan van der Molen Lab - Physics of Quantum Materials
In our lab, we investigate the physics and material properties of low-dimensional systems.
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Data science helps in speed skating race for gold
Winning gold in speed skating at the Olympic Games is not just a matter of training hard; data science can also lend a hand. Jeroen van der Eb of the Leiden Institute of Advanced Computer Science (LIACS) developed the measuring skate for this purpose, with which he recently won the Nationale Sportinnovator…
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GlobalSCAPE
Globally relevant workshop for science communication professionals
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Admission requirements
The maximum number of students that can be enrolled in the first year of the programme of the master Biomedical Sciences at LUMC is 100.
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Fire use in human evolution: A genetic approach
Are traces of fire use detectable in ancient hominin genomes?
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Partner Institutes
The IBL represents the core of modern biological research at Leiden and we interact closely with the other life science Partner Institutes in the faculty:
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About the programme
The MSc programme Computer Science offers five specialisations corresponding to the research focus areas within the Leiden Institute of Advanced Computer Science. If you would like to become a qualified teacher in Computer Science or combine our studies with science communication, you can choose one…
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Social Science Matters: Confidence in the future?
After a long period of formation, the Rutte III cabinet presented itself on 26 October 2017. The coalition agreement on which ministers will build is called ‘Vertrouwen in de toekomst’ ('Confidence in the future'). But what impact will this new cabinet have on our future? We asked our researchers in…
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Eiko Fried in APS on Open Science
Although open science reforms have contributed to a more rigorous and robust psychological science, there is still much to improve. In Association for Psychological Science (APS), Eiko Fried points out two norms that open science reforms may have overlooked so far: communalism and universalism. 'Incorporating…
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Three Leiden Science projects receive computing time on national supercomputers
A night sky of more than 40 petabytes in size, simulating young star clusters and understanding how the body inhibits viruses: three Leiden projects have received computing time on one of the national computer systems.
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Social Science Matters: Out-of-home placement
...What does seem clear, though, is that there is a great deal of room for improvement in the process of out-of-home placement. The FSW's social and behavioural scientists give their views.
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Nominees bachelor thesis prizes Political Science 2021
The nominees for the IRO thesis prize 2021 and for the Prof. Dr. J.Th.J. van den Berg prize 2021. Who wrote the best Political Science bachelor’s theses?
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Cor Veenman (NFI) researcher Forensic Big Data Science at LIACS
On December 4th an agreement was signed between the Leiden Institute of Advanced Computer Science (LIACS) and the Netherlands Forensic Institute (NFI). Cor Veenman (NFI) will perform research in the field of Forensic Big Data Science at LIACS.
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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Salma Balazadeh
Science
s.balazadeh@biology.leidenuniv.nl | +31 71 527 4790
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Science Groot funding for Leiden scientists
Leiden scientists are the main applicants for five projects that have been awarded a Science Groot grant of up to 3 million euros in the Science Domain. In addition, several Leiden scientists are involved in other projects that have been awarded funding.
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Prof. Marin van Heel awarded Wiley Prize in Biomedical Sciences 2017
Prof. Dr. Ir. Marin van Heel, Emeritus Professor at the Institute of Biology Leiden (NeCEN), is one of the winners of the “Wiley Prize in Biomedical Sciences 2017”. This annual award is presented to recognize contributions that have opened new fields of research or have advanced concepts in a particular…
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Protein motions revealed by paramagnetic NMR spectroscopy
Hass