1,851 search results for “media drug violence” in the Public website
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Researching Extremists and Terrorists: Reflections on Interviewing Hard-to-Reach Populations
In this publication, the authors explore the reality of accessing and interviewing hard-to-reach populations such as extremists and terrorists
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Moscow's Heavy Shadow: The Violent Collapse of the USSR
Moscow's Heavy Shadow tells the story of the collapse of the USSR from the perspective of the many millions of Soviet citizens who experienced it as a period of abjection and violence.
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Strategies of silence in an age of transparency: Navigating HIV and visibility in Aceh, Indonesia
Article by Annemarie Samuels in History and Anthropology
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Traditional Authority and Security in Contemporary Nigeria
This book describes the changing roles of traditional authorities in combatting contemporary security challenges.
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Hit and Lead Optimization
The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'
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Anti-establishment rhetoric helps win election for Trump
Just one year ago, nobody would have given Trump a cat's chance in the US presidential elections. Now he will be the next President of the United States. Professor of Journalism and New Media Jaap de Jong explains the rhetoric that has got Trump so far.
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NWO grant for smart software that searches for new medicines
Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…
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Cancer research focusing on quality of life
Cancer is one of the main causes of death in the Netherlands. Leiden researchers are working to improve the treatment of different types of cancer in order to increase the patient’s quality of life. A better understanding of how cancer develops will make it possible to deliver personalised and precise…
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"Normal" Feelings in "Abnormal" Worlds, On the Political Uses of Emotion in Science Fiction Manga
Carl Li defended his thesis on 30 June 2015
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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Partner Institutes
The IBL represents the core of modern biological research at Leiden and we interact closely with the other life science Partner Institutes in the faculty:
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Physicochemical analysis of allosteric binding pockets
Supervisor: Gerard van Westen
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Using AI to improve the Design-Make-Test cycle with Galapagos
Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…
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Covalent inhibitors of G protein-coupled receptors: the case of adenosine receptors
Supervisor: Xue Yang
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Polypept(o)ide-based nanostructures for therapeutic and diagnostic application
Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…
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Random walks in dynamic random environments
Promotor: W.Th.F. den Hollander
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Staphylomics: Identifying host factors involved in staphylococcal infection
How can Staphylococcus aureus bacteria subvert the host immune system?
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
PhD defence
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Frank den Hollander interviewed by CIRM
From 2 to 6 June 2014, Prof. dr. Frank den Hollander has provided 2 lectures during the workshop ‘Recent Models in Random Media’ at the Centre International de Rencontres Mathematique in Marseille (CIRM). This center facilitates workshops for mathematicians throughout the year.
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Bart Custers
Faculteit Rechtsgeleerdheid
b.h.m.custers@law.leidenuniv.nl | +31 71 527 8838
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Chat with a student
Do you have a question about studying at leiden University or student life in The Hague? Do you want more information about the Crisis and Security Management programme? Chat with a current student for answers to your questions!
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Tailor-made medicines
More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.
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AiChemist project
The AiChemist project (https://aichemist.eu) coordinated by Helmholtz Munich is an Innovative Doctoral Training Network funded through the Marie Skłodowska-Curie Actions (MSCA-DN) within the EU Horizon Research Framework, to the sum of €3 million. It brings together leading experts in AI, chemoinformatics…
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Regulation of nanoparticle biodistribution by scavenger endothelial cells (SECs)
A very large part of intravenously administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered by macrophages (Kupffer cells). To achieve effective cell-specific targeting of drugs and non-viral gene delivery vectors, improved mechanistic…
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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Societal impact
Research from the Living Lab is important for society. For example, scientists from the Living Lab discovered that the pesticide thiacloprid is up to 2,500 times more harmful to insects than was thought on the basis of regular lab research. Partly because of this discovery, the European Commission decided…
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Knowledge discovery from patient forums: gaining novel medical insights from patient experiences
Patients share valuable advice and experiences with their peers in online patient discussion groups.
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Animal-free chemical safety testing with new technology ToxProfiler
Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…
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Grants & Awards
Grants awarded to molecular physiology research
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Finding and valorizing new antibiotics using AI
Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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LED3 Lectures
The LED3 hub, consisting of researchers from the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden (IBL) and the Leiden Academic Centre for Drug Research (LACDR), is very excited to organize the “LED3 Lectures”. This lecture series brings world-leading researchers in the field of…
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Career prospects
Many students receive their first job offer during or right after their Business Studies internship. After graduating you can also aim for a career in Bio-Pharmaceutical research.
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Combatting infectious diseases; nanotechnology as a platform for rational vaccine design
Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.
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Grant for research on murder and manslaughter in the Netherlands
’25 years of fatal violence’, a collaboration of dr. Marieke Liem and prof.dr.Lenneke Alink about murder and manslaughter in the Netherlands, has received a research grant by the Leiden University Fund.
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Safety of journalists most important theme of 2022 Press Freedom Index
On 3 May, World Press Freedom Day was held and the Dutch 2022 'Persvrijheidsmonitor' was presented. The safety of journalists in 2022 was the most important theme in the area of press freedom in the Netherlands. Tarlach McGonagle, Professor of Medial Law & Information Society in Leiden, and Otto Volgenant,…
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Assistant professor "Inflammation pathways in atherosclerosis"
Science, Leiden Academic Centre for Drug Research (LACDR)
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Admission and Application
Find out how to apply for Crisis and Security Management at Leiden University by following our step-by step guide.
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Diplomacy at Leiden University
The Hague Journal of Diplomacy is hosted by the Institute of Security and Global Affairs at Leiden University. Besides the journal, there are many other activities related to diplomacy.
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Right-Wing Extremism in the Military
This research paper seeks to examine the nature of the nexus between right-wing extremism and the military by surveying five potential consequences (i.e., problem areas) arising from the presence of right-wing extremists within the armed forces of twelve Western countries.