Following the terrorist attacks in Paris (November 2015) and Brussels (March 2016), Belgium’s counterterrorism policy has been heavily criticized – domestically and worldwide.

Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?

Explaining the origins , patterns and outcomes of crisis management efforts.

The research group on governance of crises studies phenomena, dynamics and actors related to crisis governance. The Leiden University Crisis Research Center (CRC) is part of this Research Group.

The major aim is to determine the psychophysiological responses to stress and stress-management interventions and to examine the role of stress and stress-related psychophysiological mechanisms (e.g., cognitions, behaviors, and physiological stress responses) in both healthy and medical populations.

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

Data science is of vital importance in preventing future outbreaks of viruses, Professor of Data Science Aske Plaat argues. Inaugural lecture entitled ‘Data Science and Ebola’ on 13 April.

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Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Central elements in the research activities of all programme group members are: attachment, sensitive caregiving, and prevention and intervention.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

Behavioral Sciences Mental Health Psychological Disorders - Adult Aggression in Adults Psychological Science Social Psychology Criminology & Delinquency Social Sciences Criminology and Criminal Justice Crime and Crime Prevention Criminal Behaviour and Forensic Psychology Violent Crime Law Criminology…

The aim of this thesis was to study the link between hearing loss, language skills, and social functioning in deaf and hard of hearing (DHH) children. Sufficient language skills are an essential prerequisite to develop appropriate communication skills, in order to join in conversations with others.…

Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behaviour is seen. By combining interdisciplinary expertise the ACTION consortium…

Desafios para a proteção dos conhecimentos tradicionais, dos recursos genéticos e das expressões culturais tradicionais dos povos indígenas no cenário internacional

Terrorist attacks are not an end in themselves, but a means of creating unrest and fear. Terrorism policies and research should focus more on managing fear and social unrest.

Developmental and Educational psychology is concerned with the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

M. Danhof, Co-promotor: O.E. Della Pasqua

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

Decision support tool for cell therapy commercialization and business development

Assessing and implementing new diagnostics strategies for stratifying patients

Supervisor: Andrea Martella

Research on this theme addresses the systemic risks faced by European societies and affecting the quality of life of European citizens.

All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…

The European Lead Factory has been created with the ultimate goal to develop lead drug candidates to address neglected diseases including bacterial infections, psychiatric disorders and oncology.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?

Supervisor: Indira Nederpelt

Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…

The Leiden Institute of Chemistry organises and participates in several programmes for high school students and teachers.

Research on heredity and diseases is simply not possible without programmers. Curious about how you can use your IT and biology skills to deal with real-life sickness and health problems? If so, Bio-Informatics in Leiden could be something for you.

As a student of Bio-Pharmaceutical Sciences, you have a strong interest in drug development: from the onset of diseases to the effects of individual drugs in the body. Is that true for you? Then, Bio-Pharmaceutical Sciences might be the right study programme for you!

Tuberculosis bacteria and other intracellular pathogens use cells of our immune system as Trojan horses to spread into tissues. Annemarie Meijer, professor of immunobiology, explains how research into innate defence mechanisms using zebrafish inspires novel strategies for infectious disease treatmen…

PhD defence

PhD defence

PhD defence

Prof.dr. M.C. de Ruiter Prof.dr. M.J.T.H Goumans

PhD defence

PhD defence