It is the aim of this project to better understand how the physical properties of lipids influences the structure and overall barrier function of the skin.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

On 17 November 2021, Cyril-Igor Grigorieff defended the thesis 'The Regime for International Air Carrier Liability'. The doctoral research was supervised by Prof. P. Mendes de Leon and Prof. V. Correia (University Paris Saclay).

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

There is accumulating evidence for an increase in severe global drought events. In particular, Europe experienced several severe droughts in 2003, 2015, and 2018 (unprecedented in the past 2,110 years). Such droughts have caused serious and far-reaching impacts on terrestrial ecosystems.

Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.

In Luganda, the widest spoken minority language in East African country Uganda, the word for photographs is Ebifananyi. However, ebifananyi does not, contrary to the etymology of the word photographs, relate to light writings. Ebifananyi instead means things that look like something else. Ebifananyi…

The theme 'Healthy Society' is one of the focal points of the Faculty of Social and Behavioural Sciences (FSW).

Why do certain incidents of serious violence end lethally whereas others do not? What role do personal characteristics of offenders and victims play and how do immediate situational factors influence outcomes?

In response to the challenges imposed by the COVID-19 pandemic, governments worldwide adopted a variety of strategies that include not just preventive or mitigation strategies adopted to 'flatten the curve', but also interventions aiming to mitigate economic and social impacts of the pandemic.

This commentary on the United Nations Convention Against Corruption discusses each provision of the treaty, traces the provisions’ drafting history, and explores their implementation in domestic legal systems.

This article provides an in‐depth assessment of lone actor terrorists’ attack planning and preparation.

Why do communities form militias to defend themselves against violence during civil war? Using original interviews with former combatants and civilians and archival material from extensive fieldwork in Mozambique, Corinna Jentzsch (Leiden University Institute of Political Science) explains the timing,…

The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.

Misinformation has emerged as a major societal concern. But why do citizens contribute to the dissemination of falsehoods online?

The Institute of Security and Global Affairs (ISGA) is a scientific institute that specialises in security issues. The ISGA is a part of the Faculty of Governance and Global Affairs at Leiden University. The ISGA has developed from the Centre for Terrorism and Counterterrorism (CTC) and the Centre…

Binnen de masteropleiding Education and Child Studies kun je verschillende typen stages lopen.

Systems pharmacology aims to apply techniques from systems biology to pharmacological models.

This project aims to assess the risk of spread of antimicrobial resistance genes in the environment derived from currently used synthetic biology approaches in the field of drug discovery.

Large numbers of children all over the world face significant health risks, such as infectious and chronic diseases, malnutrition, injuries and the consequences of natural disasters, protracted armed conflicts and poverty.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

This new article by Monica Kaminska is part of a special issue for Journal of Cybersecurity, based on a selection of contributions from THe Hague Program for Cyber Norms' 2019 Conference.

On 1 February 2018 Nathalie-Sharon Koster defended her doctoral thesis ‘Crime victims and the police’. The doctoral research was supervised by Professor J.P. van der Leun and M.J.J. Kunst.

In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…

Technological advances have an impact on our daily lives. They have also been employed by governments to manage border security, especially at controversial border crossings. Fences, heat sensors, heat cameras, drones and other hi-tech equipment that are currently being tested collectively produce a…

This study focuses on violence involving juveniles in conflict with the law who are deprived of their liberty in different institutions within the framework of the (juvenile) criminal justice system (inter alia, police detention, pre-trial detention and deprivation of liberty after conviction or sen…

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…

The Grachtwacht (Canal Watch) conducts research on urban wildlife and the impact of plastic on nature. With our clean-ups, we not only collect waste, but also data. This way we try to find out the source of the waste and turn off the tap on shore. This way there is structurally less plastic in the c…

Wijayanto defended his thesis on 17 January 2019

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

The recent rise in global migration movements and the simultaneous attempts to prevent migrations to the Global North in general and Europe in particular have produced numerous images and narratives that try to record and convey these events and their actors.

Research on lethal violence related to criminal activities.

TRANSAUTOPHAGY is a European COST action to promote multidisciplinary research on autophagy and translation of knowledge to applications.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

In the master's programme Biomedical Sciences you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…

This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…

Terrorism only poses a small risk to people but tends to be a major source of public fear. Through fear, terrorism has far-reaching implications for public governance.

Welcome to the Social Anxiety and Specific Phobia (SASP) Research Group!

The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational and dynamic laboratory methodologies.

This project will lead to a critical edition and annotated translation of the Niśvāsamukha, the opening book of the Niśvāsatattvasaṃhitā.

This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…

Ilina Georgieva published an article in the journal Contemporary Security Policy on the norm-setting role of intelligence agencies.

The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…

The group Clinical Neurodevelopmental Sciences has expertise in individual differences in child development, in particular the development of psychopathology, ranging from mild to severe neurodevelopmental disorders.

Vaccination is the most effective method to prevent influenza infection. However, current influenza vaccines have several limitations. Relatively long production times, limited vaccine capacity, moderate efficacy in certain populations and lack of cross-reactivity are important issues that need to be…

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

In the master's programme Biomedical Sciences you learn interdisciplinary approaches to address scientific and societal challenges in the field of (bio)medical sciences. The research in our programme relates to the maintenance of health and prevention of disease. You will acquire a skill set suitable…

COUNTERRR examines domestic responses to jihadist armed groups in Africa, analyzing variation in state repression, community resistance, and the evolution of security across Mali, Nigeria, and Mozambique.