2,133 search results for “better control” in the Public website
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Information battleground: Conflict perceptions motivate the belief in and sharing of misinformation about the adversary
Misinformation has emerged as a major societal concern. But why do citizens contribute to the dissemination of falsehoods online?
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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Print referencing during e-storybook reading on a SMART board for kindergartners to promote early literacy skills
This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…
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Scheiding van zeggenschap en belang in de familiesfeer
On 1 October 2020, Arianne de Leeuw defended her thesis 'Scheiding van zeggenschap en belang in de familiesfeer'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. A.O. Lubbers.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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Who is Afraid of More Women in Politics, and Why? An Analysis of Public Opinion in 28 European Countries
In this paper, the authors study how individual and country-level variables interact in affecting political gender attitudes in Europe.
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Toward an Aesthetics by Algorithms—Palestinian Cyber and Digital Spaces at the Threshold of (In)visibility
Chapter by Fabio Cristiano and Emilio Distretti for the volume The Aesthetics and Politics of the Online Self, edited by Donatella Della Ratta, Geert Lovink, Teresa Numerico, and Peter Sarram for Palgrave Macmillan.
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Museum Studies
Museum Studies looks at museum practices from archaeological, historical and anthropological perspectives.
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The Spirit of Matter
In 'The Spirit of Matter', Peter Pels explores the significance of emotionally evocative objects, challenging the denial of their existence in modern 'mind over matter' ideology.
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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Highly Efficient Activation of HCl Dissociation on Au(111) via Rotational Preexcitation
The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Research
Biotherapeutics or biologics, such as proteins, peptides, and nucleic acids, comprise an increasing share of the pharmaceutical market, whilst offering new therapies for difficult-to-treat diseases. Most notable is their contribution to the vaccination efforts during the COVID-19 pandemic. In most cases,…
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Selective electrochemical H2O2 production by a molecular copper catalyst: A crucial relation between reaction rate and mass transport
Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Degradome analysis of vaccines
The objective is to develop in vitro antigen degradation assays in order to mimic the fate of the antigen in vivo.
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Hensen Lab - Quantum Magnetomechanics
Welcome to the Hensen Lab! We are a young dynamic experimental research group starting at the Leiden Institute of Physics. Our lab addresses one of the key challenges of modern physics: understanding the interface between quantum mechanics and general relativity.
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Justice in the Himalayas: Local Expectations and Legal Interventions
Consensus and harmony or balance and reciprocity?
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Sacrificial Landscapes
Cultural biographies of persons, objects and 'natural' places in the Bronze Age of the Southern Netherlands, c. 2300-600 BC.
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Memory in Early Modern Europe 1500 - 1800
For early modern Europeans, the past was a measure of most things, good and bad. For that reason it was also hotly contested, manipulated, and far too important to be left to historians alone.
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The infrastructure of news: Newsroom ethnography in Chile
Research on the process and construction of news stories about human rights issues in Latin American newspapers.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli
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Squaramide-based supramolecular materials for 3D cell culture applications
A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.
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Van Vollenhoven Institute
The Van Vollenhoven Institute for Law, Governance and Society (VVI) is part of the Leiden Law School.
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
- Blog Posts
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Click-to-release for immune cell activation
This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…
- Van Marum Colloquium: Guilty as charged: Electrochemical control over the charge carrier density in colloidal semiconductor nanomaterials
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OSCoffee: Better coding for reproducible research
Lecture
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Shaping innate immune responses: mechanisms that control type I interferon production
PhD defence
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Arm or Disarm: The Nexus of International Control Regimes, Disarmament and Non-Proliferation in Times of Geopolitical Tensions
Lecture
- OSCoffee: Better coding for reproducible research
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Knowledge for a Better (Global) World
Inaugural lecture
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Don’t underestimate the developing child brain
Children’s brains react in the same way to social feedback as adults’ brains. But handling frustration or aggression after being rejected is a different matter, developmental psychologist Michelle Achterberg has discovered. Using fMRI techniques, the development of the child brain has now been studied…
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Late Antiquity and early Islam
This NWO project, which is being be carried out in close cooperation with the universities of Oxford (contact: Prof. Robert Hoyland) and Princeton (contact: Prof. John F. Haldon) and the UMR 8167 (Centre National de la Recherche Scientifique, CNRS, University Paris-Sorbonne, Paris IV, University Panthéon-Sorbonne,…
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Frontex and Human Rights
Melanie Fink, Postdoctoral Researcher at the Europa Institute of Leiden University, has published her book Frontex and Human Rights, Responsibility in 'Multi-Actor Situations' under the ECHR and EU Public Liability Law. This work is based on her doctoral dissertation, which she defended in December…
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Research
The research of the group Learning and Behavior Problems in Education addresses learning difficulties in the areas of reading (technical reading and reading comprehension) math and writing, and examines learning-related behaviors behaviors.
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Microbial Sciences
In Microbial Sciences, we perform multidisciplinary research to understand the structure and function of microbes at all levels of biological organization, from small molecules and cellular structures at atomic resolution to multicellular communities.
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Programme
On this page the programme and sessions can be found. The programme will be updated regularly.
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Unlock the cyber crisis: Developing the prototype of an escape room-style cooperative game for cybersecurity education
The project aims to develop an escape room-style game to teach students cyber crisis management and prepare them for real-world cybersecurity challenges