2,242 search results for “system cell transplant” in the Public website
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The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
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More than a digital system: how AI is changing the role of bureaucrats in different organizational contexts
In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.
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pharmacometrics to optimize immunosuppressive therapy in kidney transplantation
PhD defence
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Improving survival prediction models for liver transplantation candidates
PhD defence
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Physics in the picture: cancer cells as an explosion of fireworks
When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…
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Immune system plays dual role in breast cancer
The immune system plays a paradoxical role in the spread of breast cancer. Some immune cells contribute to metastasis, while other cells can be activated to strengthen the effect of chemotherapy. Kelly Kersten made this discovery in her PhD research. PhD defence 7 February.
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A chemical connection that affects your immune system
A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.
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MICA-mediated immunity: a new opportunity for improving corneal graft survival
Corneal transplantation is one of the most common human organ transplantations worldwide. Although the 1-year survival rate is as high as 90%, more than half of transplantation patients suffer various types of corneal rejection, such as epithelial rejection, chronic stromal rejection, and endothelial…
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Scattering and absorption in 2D optics
Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.
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Professor Ewa Snaar-Jagalska appointed professor in the field of cellular tumor biology
From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish
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Pharmacometabolomics; prediction of system-wide multi-biomarker drug response
The lack of success of new CNS drugs in clinical development is in part due to the complexity of the CNS, unexpected side effects, difficulties for drugs to penetrate the brain, but also by the lack of biomarkers.
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Spinoza Prize for Leiden cell biologist, immunologist and chemist Sjaak Neefjes
Sjaak Neefjes, Professor of Chemical Immunology at Leiden University, will receive the NWO Spinoza Prize this year. The Spinoza Committee called Neefjes an ‘exceptional researcher whose intelligence is matched by his boldness’. He will use the 2.5 million euro prize to pursue his research into cancer…
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Macrophages and atherosclerotic lesions-projects
For more information regarding ongoing research projects, please contact Prof. Miranda van Eck.
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Sarantos Kostidis
Dr. in Biomedical NMR spectroscopy, LUMC, Leiden - The Netherlands
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Key publications
Key publications of the Antiviral Pharmacology group.
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Development of cross-protective influenza A vaccines based on cellular responses
Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…
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Shielding software systems: A comparison of security by design and privacy by design based on a systematic literature review
The authors systematically search and review relevant definitions of Security by Design (SbD) in comparison with Privacy by Design (PbD).
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Berent Baris
Science
b.t.baris@cml.leidenuniv.nl | +31 71 527 2727
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José Mogollón
Science
j.m.mogollon@cml.leidenuniv.nl | +31 71 527 7166
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Willem Meilink
Science
w.r.m.meilink@biology.leidenuniv.nl | +31 71 527 4882
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Xinpeng Jin
Science
x.jin@cml.leidenuniv.nl | +31 71 527 2727
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Arko Ghosh
Faculteit der Sociale Wetenschappen
a.ghosh@fsw.leidenuniv.nl | +31 71 527 5123
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Isabel Siles Asaff
Science
m.i.siles.asaff@cml.leidenuniv.nl | +31 71 527 2727
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Roosje Peeters
Faculty of Humanities
r.m.m.peeters@hum.leidenuniv.nl | +31 71 527 2699
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Connecting dots between natural and artificial Photosynthesis
Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?
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Louwerse, ‘The predictive value of polls in a fragmented multi-party system’
Political scientists Tom van der Meer, Lisa Janssen (University of Amsterdam) and Tom Louwerse (Leiden University) analyse polls presented by the main polling agencies in the Netherlands, as well as micro-level panel data. They reach three main conclusions. First, vote intention polls in the Netherlands…
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Alireza Mashaghi Tabari
Science
a.mashaghi.tabari@lacdr.leidenuniv.nl | +31 71 527 4425
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
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The Metallophilic Interaction between Cyclometalated Complexes: Photobiological Applications
In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.
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Structural and functional analysis of proteins involved in natural product biosynthesis and morphological differentiation in Streptomyces
Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.
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Solvent tolerance mechanisms in Pseudomonas putida
Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.
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How Bio-questionable are the Different Recombinant Human Erythropoietin Copy Products in Thailand?
The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market.
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Sukamiskin: Utilisation of the Plural Health Information and Communication System in the Sunda Region of West Java, Indonesia
This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.
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Leiden Spinoza and Stevin Prize laureates
Of the 109 Spinoza Prizes that have been awarded since 1995, 26 have gone to researchers from Leiden University. The NWO Spinoza Prize is the highest Dutch award in science. The younger NWO Stevin grant goes to researchers who have achieved great success in the field of knowledge utilisation for society.…
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Remko Offringa
Science
r.offringa@biology.leidenuniv.nl | +31 71 527 5097
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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political terrorism: The formation and destruction of the two-party system in the Red River Valley of Louisiana, 1865-1868
The project examines the political conflict in the Red River Valley of Louisiana between the majority-black Republican Party and the overwhelmingly white Democratic Party by studying the composition and actions of each party.
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Activity-Based Proteasome Profiling
Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea
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Three new Leiden members of KNAW
KNAW has elected eighteen new members, including two professors at Leiden University and one who studied and obtained his PhD in Leiden. The New Academy members will be installed at a later date this year.
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Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
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Innovating Cell Pharmacy with stem cells
Lecture
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Policy brief on 'Deepening G20-UN System Cooperation to Foster Socio-Economic Recovery from the Pandemic and Reduce Inequality Worldwide'
This Think20 (T20) policy brief recommends the introduction of a