On 10 May, GTGC Chair Prof. Jan Aart Scholte, presented the paper ‘Legitimacy in Global Governance: A Cross-Level Analysis’ at the European University Institute (EUI) in Florence, Italy.

On 27 and 28 April, Simona Demková participated as a panelist at the conference 'A

This Think20 (T20) policy brief recommends the introduction of a

During the honours programme’s start of the year event of September the 15th, Pierre van Eijl and Albert Pilot were invited to talk about their research on talent development in honours programmes and the honours laboratory for 21st century skills. The honours programme with a new name is ‘Tackling…

At two recent events, Ben Van Rompuy, Assistant Professor of competition law at the Europa Institute in Leiden, discussed current developments in the application of EU competition rules to regulatory aspects of sport.

PhD defence

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

How can zebrafish research help understanding human diseases?

How is Pol θ responsible for T-DNA integration, and how do other DNA double-strand break repair pathways interact with Pol θ? How may we manipulate T-DNA integration to stimulate error-free integration at a predetermined genomic site?

The Dutch press has given the anniversary exhibition in the Leiden Meelfabriek some rave reviews: ‘Global Imaginations is amusing and confrontational.’ The exhibition celebrates the 440th anniversary of Leiden University and can be seen until 5 October.

Dr Amy Strecker (Heritage Dept., Faculty of Archaeology) has recently been awarded a LGI BREED grant to develop her project on property and spatial justice in international law. Building on her previous research into landscape protection from cultural heritage, environmental and human rights perspectives…

Launched in early March, GlobalSCAPE is an EU-funded project seeking to understand the current state of science communication globally, especially in non-western countries. Through the Department of Science Communication & Society, Leiden University is one of the main partners of the project, which…

The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…

Promotor: B. van de Water

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

Can new variants of daptomycin and the polymyxins be found?

Supervisor: P.J.J. Hooykaas

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

Promotor: G.P. van Wezel

The Horizon 2020 project CoSTREAM aims to improve our understanding of the co-occurrence of stroke and Alzheimer’s disease. It has long been known that both diseases share underlying causes, but their exact interaction or link is not fully understood. CoSTREAM combines multiple factors to identify and…

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?

How does FoxP1 affect auditory perception on a behavioural and genomic level?

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Promotor: Prof.dr. J. Memelink

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Cultural and individual differences

The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…

This summer the department of Labour Law at Leiden University will start a new tradition of an annual summer school addressing current issues in labour law from an international, transnational and European point of view. With a mixture of lectures, seminars and a field trip, topics will be explored…

Leiden University has taken seventh place in the UI Green Metric, a global sustainability ranking for universities. Almost 1,000 universities from all over the world participate in the ranking.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.