2,165 search results for “berger control” in the Public website
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Countering Terrorist Narratives: Assessing the Efficacy and Mechanisms of Change in Counter-narrative Strategies
This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…
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Structure and substructure in the stellar halo of the Milky Way
Promotor: K.H. Kuijken
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The Imperialisation of Assyria: An Archaeological Approach
The Assyrian Empire was the first state to achieve durable domination of the Ancient Near East, enduring some seven centuries and, eventually, controlling most of the region. Yet, we know little about how this empire emerged from a relatively minor polity in the Tigris region and how it managed to consolidate…
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PhD Research
Leiden Law School is a high-standing institution in the field of research and education in law and aims to further strengthen this position. Receiving a PhD degree is considered as proof of competence in independently conducting scientific research.
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Improving the filamentous fungus Aspergillus niger as cell factory for starch degrading enzymes
We aim to develop A. niger strains that produce more starch degrading enzymes even in the absence of starch.
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The Imperial Discipline: Race and the Founding of International Relations
This book questions the accepted origins of the field of International Relations (IR). Commonly understood to have emerged from the horrors of WW1 with the goal of bringing about world peace, the authors argue that on the contrary, IR came from a somewhat less noble tradition – that of the Round Tab…
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Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Pedagogies of Prohibition: Time, Education, and the War on Drugs in Rio de Janeiro’s Zona Norte
Benjamin Fogarty-Valenzuela published the article 'Pedagogies of Prohibition: Time, Education, and the War on Drugs in Rio de Janeiro’s Zona Norte' in Cultural Anthropology 37. The article’s three sections focus on three forms of temporal control—busyness, punctuality, and rhythm—and each demonstrates…
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Endocannabinoids in health and stress
How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Consular diplomacy's first challenge: Communicating assistance to nationals abroad
Jan Melissen, Senior Fellow International Relations and Diplomacy at ISGA, researched the topic of consular diplomacy in a digital age. Specifically: the communicative challenge.
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Inducing spin triplet superconductivity in a ferromagnet
Promotor: J. Aarts
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The role of research in university teaching: a comparison of Chinese and Dutch teachers
This dissertation reports on the beliefs and perceptions of Chinese and Dutch university teachers regarding the role of research in university teaching and how these beliefs and perceptions can be explained by their cultural, institutional and individual background characteristics
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Participation, Engagement and Collaboration in Newsmaking
This book brings together new research on the practices of newsmaking.
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Descolonizando Tiempo, Espacio y Conocimiento
El pueblo Kamëntšá en la encrucijada del patrimonio cultural
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El almirantazgo y la armada de los Países Bajos durante los reinados de Felipe I y Carlos V
This book investigates how the rulers of the Habsburg world empire developed and implemented a central maritime policy for the Netherlands and appointed an admiral of the sea or admiral-general for that purpose.
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OPERA – Open Research Analytics
OPERA aims at establishing open and advanced research analytics practices and systems at Danish universities and in the Danish landscape of research analytics stakeholders.
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Zheng Li, Promoting Harmony with Conflicts?
This dissertation focuses on the production and consumption of a mediation show in China that collaborates with the local Justice Bureau and broadcasts on an entertainment channel—exploring answers to questions raised from the mentioned entertainisation, social and political, and cultural issues.
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Institute for Philosophy
The members of the Institute for Philosophy study all aspects of philosophy. In our research we seek a fruitful interaction between systematic and historical approaches to philosophy, and we thrive on intensive national and international collaboration.
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Information battleground: Conflict perceptions motivate the belief in and sharing of misinformation about the adversary
Misinformation has emerged as a major societal concern. But why do citizens contribute to the dissemination of falsehoods online?
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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Print referencing during e-storybook reading on a SMART board for kindergartners to promote early literacy skills
This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…
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Scheiding van zeggenschap en belang in de familiesfeer
On 1 October 2020, Arianne de Leeuw defended her thesis 'Scheiding van zeggenschap en belang in de familiesfeer'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. A.O. Lubbers.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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Who is Afraid of More Women in Politics, and Why? An Analysis of Public Opinion in 28 European Countries
In this paper, the authors study how individual and country-level variables interact in affecting political gender attitudes in Europe.
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Toward an Aesthetics by Algorithms—Palestinian Cyber and Digital Spaces at the Threshold of (In)visibility
Chapter by Fabio Cristiano and Emilio Distretti for the volume The Aesthetics and Politics of the Online Self, edited by Donatella Della Ratta, Geert Lovink, Teresa Numerico, and Peter Sarram for Palgrave Macmillan.
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Museum Studies
Museum Studies looks at museum practices from archaeological, historical and anthropological perspectives.
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The Spirit of Matter
In 'The Spirit of Matter', Peter Pels explores the significance of emotionally evocative objects, challenging the denial of their existence in modern 'mind over matter' ideology.
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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Highly Efficient Activation of HCl Dissociation on Au(111) via Rotational Preexcitation
The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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SysMedPD: Systems Medicine of Mitochondrial Parkinson's Disease
The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Research
Biotherapeutics or biologics, such as proteins, peptides, and nucleic acids, comprise an increasing share of the pharmaceutical market, whilst offering new therapies for difficult-to-treat diseases. Most notable is their contribution to the vaccination efforts during the COVID-19 pandemic. In most cases,…
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Selective electrochemical H2O2 production by a molecular copper catalyst: A crucial relation between reaction rate and mass transport
Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Degradome analysis of vaccines
The objective is to develop in vitro antigen degradation assays in order to mimic the fate of the antigen in vivo.
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Hensen Lab - Quantum Magnetomechanics
Welcome to the Hensen Lab! We are a young dynamic experimental research group starting at the Leiden Institute of Physics. Our lab addresses one of the key challenges of modern physics: understanding the interface between quantum mechanics and general relativity.
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Justice in the Himalayas: Local Expectations and Legal Interventions
Consensus and harmony or balance and reciprocity?
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Sacrificial Landscapes
Cultural biographies of persons, objects and 'natural' places in the Bronze Age of the Southern Netherlands, c. 2300-600 BC.
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Memory in Early Modern Europe 1500 - 1800
For early modern Europeans, the past was a measure of most things, good and bad. For that reason it was also hotly contested, manipulated, and far too important to be left to historians alone.