6,432 search results for “based” in the Public website
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Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Projects
With our research, we aim to enrich academic and practical knowledge on the governance of sustainability, as well as contribute to public debates on these issues. For that purpose, we strive for diversity in our research subjects, research methods and theoretical approaches. Our research covers different…
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Doris Jacobs
Dr. Doris M. Jacobs, Lead Scientist at Unilever R&D, Wageningen, The Netherlands.
- Matthieu Schaller Group - Numerical Cosmology
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
- Results
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Josephson and noise scanning tunneling microscopy on conventional, unconventional and disordered superconductors
In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…
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Identification of novel targets in prostate cancer progression
Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen
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CO2 reduction on post-transition metals and their alloys: an industrial approach
This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals
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Figuring Things Out Together: On the Relationship Between Design and Collective Practice
Anja Groten investigates matters of collectivity, drawing from the experience of working with the Amsterdam-based collective Hackers & Designers (H&D)*.
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Career prospects
After graduation you are well equipped to start a career in evolutionary research or to take the responsibility for projects in an industrial or institutional research environment.
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Career prospects
Completing your Master’s in Biology gives you an internationally recognised degree which you can follow up with a PhD track. With your acquainted skills, you’re a much requested professional in and outside research.
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Strategy
The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.
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Computational Linguistics
In this theme you will be supplied with a firm background in the core of current computational linguistics and a solid comprehension of its neighboring fields.
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Teachers’ practical knowledge and lesson design in the context of innovation
This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…
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Sustaining Ethical Aquatic Trade (SEAT)
Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.
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Highly sensitive analysis using 3D cell culture model
A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…
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People and Projects
Our team consists of the following members.
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ANO-NET: Anonymity in Complex Networks
This project develops methods for ensuring the anonymity of individuals in social network data.
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ELSA Lab Defence
Embedding ethical legal and societal aspects for responsible military AI.
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Laborinth II: Thinking as experiment- 472 meditations on the necessity of creative thinking and experimenting in the performance practice of
The thesis wishes to examine the pathways of thought underlying the creative act of music making and the performance practice of complex music from the late twentieth and early twenty-first century.
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Spatial patterns in landscape archaeology (publication)
In several Mediterranean regions archaeological sites have been mapped by fieldwalking surveys, producing large amounts of data. These legacy site-based survey data represent an important resource to study ancient settlement organization. Methodological procedures are necessary to cope with the limits…
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Polymers in the Liver: Metabolism and Regulation
Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational…
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Film and Photographic Studies (MA)
The master’s programme in Film and Photographic Studies at Leiden University covers the history and theory of film and photography within the broad context of visual and other media.
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Planning for a World beyond COVID-19: Five Pillars for Post-Neoliberal Development
In this opinion article published in World Development, the authors present five research and policy priorities. While it is clear that ‘pluriversal’ designs need to guide the way forward (Kothari et al 2019), defining a set of key pillars can provide direction and purpose across this pluriversality.…
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About the programme
The Astronomy and Science Based Business specialisation consists of 120 European Credit Transfer System (EC) points and includes a one-year astronomy component (60 - 80 EC) and a business component in the second year (40 - 60 EC).
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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Migraine@Work: work ability in employees with migraine
This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?
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Musika: The becoming of an artistic musical metaphysics
“Music is about everything else,” theater director Peter Sellars said upon accepting his Polar Music Prize back in 2014. Although it is about particular musical problems, Stanimiras dissertation is about ‘everything else’, too. What and how that is, could be summed up in different ways depending on…
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Testimonials
Read about experiences of former students.
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Prediction of human (CNS) target site concentrations in health and disease
Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…
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Computational facilities
Beowulf clusters looking for new frontiers.
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Programme structure
Learn to use a visual ethnography framework in each phase of the research process.
- About the programme
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Clean diesel and dirty scandal: The echo of Volkswagen’s dieselgate in an intra-industry setting
In 2015 the U.S. Environmental Protection Agency revealed that German car manufacturer Volkswagen had illegally installed software to produce fake NOx-emissions results. This study aims to analyze how the German news media framed VW’s role.
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Research
Research lines within the Pharmacy group:
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Using smartphone behaviour to understand healthy ageing and neurological disease
Leiden University researchers and their collaborators report the development of new research frameworks that use day-to-day smartphone behavior gathered from a large sample of healthy people to help understand aging, and how aging alters with epilepsy and stroke. These reports occupy two back-to-back…
- Programme
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Start-Ups
The entrepreneurial spirit is highly present among the SBB students. The many (successful) spin-off companies from Leiden University brought by (former) SBB students are proof of this.
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Seascape Corridors: How modelling routes through the sea can illuminate early island culture
What are the capabilities or limitations of traveling between islands and how does this reflect seasonal variation? Is it possible to show higher levels of connectivity between islands based on generated pathways between several sites on two separate islands?
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Joachim Kopka
PhD at the Max Planck Institute of Molecular Plant Physiology, Golm – Germany
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H2 steel
What are the possibilities of converting biowaste streams into value added products? What current and future technologies will enable this transition with minimal environmental and economic costs? The researchers in H2 steel project will enable the transition of sewage sludge into green hydrogen, steel…