Zebrafish is an excellent model organism for studying various human diseases. Due to opaqueness of the adult phase, in vivo studies are restricted to early embryonic stages. This raises the need for rapid sensitive and non-invasive in vivo imaging methods to follow developmental processes, not only…

Facilitating direct citizen participation through online channels is considered as an opportunity for including harder to reach groups in participation.

Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

On December 11th, Andreea Geambasu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreea on this great result.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Is the current existing legal framework on compulsory and voluntary care - for vulnerable young adults (between the ages of 18 to 23) - in need of revision? And if so, what kind of amendments would be advisable?

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The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.

Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…

On Monday November 7th the research outcome ‘Involuntary (after) care for vulnerable young adults? A study to the legal possibilities for the provision of (involuntary) care to vulnerable young adults after child protection’ was presented to the members of the Parliament.

On Friday 16 April, the webinar 'Children and young adults in contact with the law: Systemic vulnerabilities and institutional responses' will take place. The webinar is organised by Eva Schmidt LL.M, Dr. Anna Pivaty (Radboud University/Maastricht University) and Dr. Stephanie Rap, with the support…

On 16 April 2021 the webinar ‘Children and young adults in contact with the law: Systemic vulnerabilities and institutional responses’ took place. In total 17 speakers and discussants engaged with the topic of vulnerability.

It can seem like an almost childish mistake, but a surprising number of adults confuse left from right. Neuroscientists are only just starting to know more about directional and navigation and understand why it is so difficult to distinguish left from right . Ineke van der Ham is an expert on navigation.…

Behavioral and neural mechanisms underlying risky decision-making in adolescents

What starts off gently may end dramatically. Many young people these days fall victim to sexual exploitation. How can we prevent this suffering? Ieke de Vries points to the living environment of (potential) victims.

Lecture, Com(parative) Syn(tax) Series

PhD defence

ADHD & ME aims to explore how enhancing self-esteem can break the relation between ADHD symptoms and comorbid disorders, such as anxiety and depression. In this study we assess the effectiveness of a Cognitive Behavioural Therapy (CBT) program called Competitive Memory Training (COMET) for improving…

PhD defence

How can we improve quality of life and study success in young, high-functioning adults with autism?

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

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Clearance is the most important pharmacokinetic parameter for drug dose selection. Pharmacokinetic information is typically first available in the adult population, and in general only limited pharmacokinetic data are available in children when drugs enter into the market. It is therefore of the utmost…

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Education and Organisation Development

Can playing certain games decrease cognitive decline or even enhance cognitive performance in the aging population?

We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…

During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?

During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!

Platform Opleiding, Onderwijs en Organisatie Ltd (PLATO). PLATO is committed to learning, learning in schools, learning in work environments, learning in life and life.

A neurobiological perspective on individual differences in social competence

Across cultures, parents help their children master the social and linguistic codes needed in adult life. Recent research on language socialization found important cross-cultural differences, pointing out the need for more diversity for a full understanding of this process.

This project introduces primary school children (8-12 years) to science and archaeology.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Lecture

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…

Everyone is welcome at the Leiden Science Family Day. We have set up a programme with a variety of activities for children, teenagers and adults.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

PAIR, Psychoeducational Assessment, Intervention and Rehabilitation, is the online Open Access journal associated with ENPAIR.

Mapping the neural mechanisms underlying social motivations of adolescents and adults

PhD defence

PhD defence

Leiden University has much to offer, so why not come and visit? We’d like to meet you.

Edegar da Conceição Savio defended his thesis on 28 January 2016