113 search results for “placebo” in the Public website
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Topic: Placebo effects
The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…
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Center for Interdisciplinary Placebo Studies Leiden
The Center for Interdisciplinary Placebo Studies Leiden (IPS) aims to advance the understanding of placebo and nocebo effects, their underlying mechanisms, and their potential applications in clinical practice. IPS consists of a group of interdisciplinary researchers working at Leiden University with…
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Open label placebo for itch
Positive expectations can influence sensations of itch and evoke placebo effects, whereas negative expectations can trigger nocebo effects in itch. There is evidence that placebo effects can occur even when people know that they are taking a placebo. Little is known about how these so-called open-label…
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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“Special Needs by Placebo”: Programme to Advise, Normalize And Control its European Administration (PANACEA)
While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…
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Do placebos help against itching?
If a pill containing no active ingredients still helps, this positive expectation is called a placebo effect. A negative expectation is called a nocebo effect. Both can be produced by verbal suggestions and conditioning. According to Andrea Evers’ research group, combining these is the most promising…
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First guidelines for applying placebo effect in clinical practice
It is becoming increasingly clear that the placebo effect has a great influence on medical treatment. An international, interdisciplinary team of researchers led by Professor of Health Psychology Andrea Evers from Leiden University has now written a first set of guidelines on how to apply the placebo…
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Pavlov revisited. About the placebo effect of rose scent
Health psychologist Aleksandrina Skvortsova has made clever use of the Pavlov effect to link the ‘cuddle’ hormone oxytocin with the placebo effect. This effect can alter the level of oxytocin in the body, making it possible for people to reduce the amount of medicine they need while still feeling good.…
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Podcast: The magic behind a placebo
Sometimes fake medicine is enough to cure a patient. But how exactly do placebos work? And did you know that there is also the placebo effect in reverse, the nocebo effect? Psychologist Stefanie Meeuwis explains in this Science Shot.
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Using the placebo effect for your health
Even if you have a healthy lifestyle, there's a lot to experience and learn during the Healthy University Week, from 26 to 30 October. Health psychologist Andrea Evers is enthusiastic about the week ahead. She tells us about the programme and gives us a taste of her own talk on what the placebo effect…
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Lingling Weng aims to improve clinical practice with placebo and nocebo effects
The placebo effect was completely new to her when Lingling Weng began the PhD project in Leiden. She is now a postdoc in China. 'It would be great to investigate the underlying mechanisms of placebo and nocebo effects with my current knowledge of EEG and fMRI.' PhD defence on 17 October.
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The placebo effect: first world congress in Leiden
Medicines can work even if they have no active ingredient. The first international scientific conference on placebos will take place in Leiden from 2 to 4 April. Placebo researcher Andrea Evers, who is also chairing the conference, answers some pressing questions.
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Fabian Wolters
Faculteit der Sociale Wetenschappen
f.wolters@fsw.leidenuniv.nl | +31 71 527 2727
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Knowledge to the neighbourhood about the placebo effect
The tuk-tuk of the European City Of Science Leiden 2022 sent science on its way to the neighbourhood. On the Vijf Meiplein in Leiden, Andrea Evers' placebo team pitched its tent to everyone who wanted to know more about the effect of words and expectations. Experience the day of the placebo effect in…
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New centre of expertise makes placebo research accessible for healthcare and society
Positive expectations about treatment increase the likelihood of success. The new Center for Interdisciplinary Placebo Studies Leiden is therefore promoting research on the placebo effect and offering expertise and training for care providers. At the opening, the founders demonstrated their VR communications…
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Liesbeth van Vliet
Faculteit der Sociale Wetenschappen
l.m.van.vliet@fsw.leidenuniv.nl | +31 71 527 2727
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COMMUNICATE HEAL-TH. A Virtual Reality training tool for optimizing expectancy effects in patient-provider interaction.
We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.
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Henriët van Middendorp
Faculteit der Sociale Wetenschappen
h.van.middendorp@fsw.leidenuniv.nl | +31 71 527 6333
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Antoinette van Laarhoven
Faculteit der Sociale Wetenschappen
a.vanlaarhoven@fsw.leidenuniv.nl | +31 71 527 6634
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Topic: Psychopharmacology in Health and Medical Psychology
In this research line, the role pharmacological agents and neurochemcial processes play in behavior and cognition is examined with a particular focus on pain, placebo and nocebo effects and intensive care treatments.
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Aleksandrina Skvortsova
Faculteit der Sociale Wetenschappen
a.skvortsova@fsw.leidenuniv.nl | +31 71 527 2727
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Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst
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Generalization of placebo and nocebo effects on somatosensory sensations
PhD defence
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Andrea Evers installed as a new KNAW member
Health psychologist Andrea Evers is one of the 19 new members, selected by the Royal Netherlands Academy of Arts and Sciences (KNAW), who have been inaugurated on 16 September 2019. The Academy has now about 550 members.
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Innovative diagnostics and treatments
The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…
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Topic: Work and health
The research connected to this topic is related to Work and health.
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'There's nothing more we can do for you' - New publication on harmful communication in oncology
PhD student Janine Westendorp and her colleagues conducted literature research on what patients with cancer and their loved ones perceive as harmful communication from healthcare providers. The results were published in the journal Psycho-Oncology and are released as a poster to distribute to healthcare…
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Andrea Evers
Faculteit der Sociale Wetenschappen
a.evers@fsw.leidenuniv.nl | +31 71 527 6891
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Michiel van Elk
Faculteit der Sociale Wetenschappen
m.van.elk@fsw.leidenuniv.nl | +31 71 527 2727
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Topic: Psychological factors in Itch and pain
Since itch and pain can be very burdensome, especially when individuals suffer from (either of) these symptoms chronically, it is important to know the factors by which these sensations are influenced. It becomes more and more clear that psychological factors play an important role in the experience…
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Learning to perceive: Psychological and neural processes underlying placebo and nocebo effects on cutaneous sensations
PhD defence
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Hebben reumapatiënten met hulp van placebotechnieken minder medicatie nodig?
From painful joints to intense fatigue: a third of rheumatism patients suffer serious effects from this chronic condition and rely long-term on medication. Leiden psychologists are to receive a subsidy from the Netherlands Arthritis Foundation to investigate whether placebo techniques can help patients…
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Pharmacological conditioning of oxytocin responses in healthy volunteers
Is it possible to pharmacologically condition oxytocin responses in healthy individuals and identify the neural circuitry underlying such conditioning?
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The magic of healing
In his book The magic of healing, Willem van der Does talks about 14 pioneers in the history of psychiatry. These pioneers all had one thing in common: they started with a radical idea which led to great enthusiasm.
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Gut Feelings: Vagal Stimulation Reduces Emotional Biases
Stimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions. This research study by psychologists Katerina Johnson and Laura Steenbergen is published in the journal Neuroscience, and made it to the cover.
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Topic: E-health
The research connected to this topic is related to E-health.
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Andrea Evers wins Stevin Prize for knowledge exchange and impact
Andrea Evers, Professor of Health Psychology at Leiden University, has won the Stevin Prize – alongside the Spinoza Prize, the highest scientific award in the Netherlands. She is the third social scientist from Leiden in a row to win one of these prizes. ‘Leiden attracts freethinkers.’
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Kaya Peerdeman wins award for article on analgesia
Health psychologist Kaya Peerdeman has won the article award of the Postgraduate School For Research and Education in Experimental Psychopathology (EPP) for the best academic paper in 2015-2016. Published in European Journal of Pain on 19 April 2017.
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Our expectations shape our health
Positive expectations about a medicine may help it to work more effectively, even if you tell patients about this placebo effect. The reverse, the nocebo effect, works in the same way. Health psychologist Stefanie Meeuwis found evidence for this in various studies. PhD defence 3 June.
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Psychophysiological responses to stress and stress management
The major aim is to determine the psychophysiological responses to stress and stress-management interventions and to examine the role of stress and stress-related psychophysiological mechanisms (e.g., cognitions, behaviors, and physiological stress responses) in both healthy and medical populations.
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Two Veni grants awarded to Leiden Psychology researchers
Two Leiden researchers of the Institute of Psychology have been given the opportunity to realise their research plans for the coming three years thanks to a Veni grant from the Netherlands organisation for scientific research. Hanneke Hendriks is researcher in the field of Social and organisational…
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Topic: Spatial thinking
Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…
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Evaluation and implementation of innovative diagnostics and treatment
If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Expectations can relieve pain
To relieve a patient's pain, it can be effective to induce expectations. This finding is promising for optimising the effectiveness of treatments, conclude Kaya Peerdeman and colleagues in their article in PAIN.
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Imagination can reduce pain
If you imagine in advance that something is not going to hurt, this could mean you experience less pain. This discovery was made by health psychologist Kaya Peerdeman during her PhD research on the placebo effect. PhD defence 7 February.