Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Leiden is easily accessible by public transport. The city is ideally situated just a stone's throw from major cities like The Hague and Amsterdam. For those travelling to Leiden by plane, we are pleased to announce that KLM offers discounts for Speech Prosody attendees.

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

The research group of Semonti Bhattacharyya at the Leiden Institute of Physics studies quantum transport measurements in Van der Waals heterostructures.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

This thesis describes a study from both a theoreticaL and an experimental point of view.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.

Promotor: S.M. Verduyn Lunel

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

The territories that would make up what is today the Republic of Zambia officially became British in 1891. However, this did not equate to an on-the-ground presence of colonial authority capable of affecting the destiny and daily lives of people.

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Over the past decades within the European Union (EU), economic proliferation and globalisation have resulted in an increase in transboundary waste transportation. Although waste trading can often have positive economic and environmental impacts by repurposing natural resources within industrial sectors,…

Barend Barentsen, Professor Labour Law, talked about the local public transportation strikes in the Netherlands with Omroep Gelderland.

On 6 December 2022, the International Air Transport Association (IATA), which represents around 260 airlines in the world, released its Economic Outlook & State of the Industry, projecting that globally airlines would return to profit in 2023.

For one week, regional public transport drivers will go on strike. At least, that is what Dutch trade unions FNV and CNV are calling for. According to the employers’ association WVOV, half the busses will still be running.

Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…

In unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of superconductors: Weyl superconductors, and the Fu-Kane heterostructure.

Meeting in person is crucial to higher education. It would therefore be inadvisable only to allow students to use public transport between 11:00 and 15:00. This is what the rectores magnifici of the Dutch universities say in a joint letter in ScienceGuide.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Livestock was already transported over long distances in the Bronze Age Netherlands. That is what researchers from Leiden University and VU Amsterdam have discovered. Publication in the Journal of Archaeological Science: Reports.

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Promotor: Prof.dr. C.W.J. Beenakker

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

PhD defence

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Promotor: A. Kros

The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…

The energy and water consumption and CO2 footprint of all buildings at Leiden University can now be seen on its new Duurzaam in Beeld website. ‘We do a lot about sustainability,’ says Jeroen Waijenberg, Sustainability and Energy Coordinator at the University’s Real Estate Directorate. ‘But our efforts…

Wat zijn de huidige energiekosten en hoe is de comfortbeleving het wooncomfort in een bepaalde groep huurders van woningcorporatie Portaal?

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

A selection of recent publications from the Plant BioDynamics Laboratory.