10 search results for “natural products” in the Public website
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Hannah AugustijnScience
h.e.augustijn@biology.leidenuniv.nl | 071 5274791
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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Anna RoseboomScience
j.m.roseboom@biology.leidenuniv.nl | +31 71 527 4395
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Niels van der WindtScience
n.van.der.windt@cml.leidenuniv.nl | 071 5272727
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Anthracycline biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Sandra IrmischScience
s.irmisch@biology.leidenuniv.nl | +31 71 527 2727
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Paul KesslerScience
p.j.a.kessler@hortus.leidenuniv.nl | +31 71 527 5235
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Robert VerpoorteScience
verpoort@chem.leidenuniv.nl | +31 71 527 4528
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This is the library you did not know you had been looking for
2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…