2,334 search results for “mexican drug violence” in the Public website
-
In vivo tracking and biodistribution of protein aggregates
Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…
-
Marieke Liem in The Economist on drug-related murders in Europe
Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years
-
the role of Dutch Intelligence Services (AIVD) in the fight against drug trafficking
Minister Grapperhaus wants to use intelligence services in the investigation of drug crime. There are many doubts about this wish in the intelligence world. Paul Abels, Professor by Special Appointment Governance of Intelligence and Security Services at the Institute of Security and Global Affairs (ISGA),…
-
Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
-
Protecting Places of Worship in Europe: a Review of Literature and Future Research Trends
In this publication, May Tamimova and Tahir Abbas researched the existing literature about violence and hatred against places of worship.
-
Carlotta Rigotti attends UNFPA Moldova
In anticipation of future legal reforms on gender-based violence in the Republic of Moldova, Dr Carlotta Rigotti was invited by the United Nations Population Fund to participate in a roundtable discussion on legislative and policy approaches to online and technology-facilitated violence.
-
Bob van de Water
Science
water_b@lacdr.leidenuniv.nl | +31 71 527 6223
-
First comprehensive study on gun violence in Europe identifies alarming trends
The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…
-
Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
-
Experimental drug BIA 10-2474 deactivates proteins in human nerve cells
At high doses, drug candidate BIA 10-2474 binds not only to the protein that it targets, but to other proteins as well. It thus deactivates proteins that are involved in the metabolism of nerve cells. This is what an international group of researchers from Leiden University and Erasmus MC, among others,…
-
New measuring method facilitates drug research
Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.
-
Predicting drug behaviour in the brain
Does a drug enter into the human brain once administered in the body?
-
About this minor
Urban riots, violent responses by police, drug-related assassinations, child abuse, bar fights: Violence is a core theme in today’s modern society.
-
Drugging the undruggable: NWO Open Competition grant for Alireza Mashaghi
Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…
-
Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
-
Combatting violence against children: what are the lessons learnt?
In the context of the 2021 Day of General Discussion of the UN Committee on Rights of the Child, this time dedicated to alternative care, Defence for Children in collaboration with Leiden University has contributed with a paper on the 2019 Dutch Inquiry Committee on Historical Child Abuse in Alternative…
-
Orange the World: Visible and invisible violence against women
On 25 November, the global 16-day campaign 'Orange the World' against violence against women and girls started. Leiden University will also be paying attention to this campaign. On Friday 9 December, Renate van der Zee and Marieke Liem will give a lecture at the Campus The Hague (Spanish Steps, Wijnhaven)…
-
Psychologist writes sober book about psychedelic drugs
Psychedelic drugs like magic mushrooms and LSD are embraced by some and seen as lethal by others. Cognitive psychologist Michiel van Elk delved into the world of psychedelic drugs and wrote a surprisingly sober book about them. ‘Without first-hand experience my story wouldn’t be complete.’
-
Proving discriminatory violence at the European Court of Human Rights
On Tuesday 23 May 2017, Jasmina Mackic will defend her doctoral thesis ‘Proving discriminatory violence at the European Court of Human Rights’. The defence will start at 15.00 hrs, at the Academy Building of Leiden University, Rapenburg 73. The supervisor of the research is Vice Dean and Professor of…
-
Academy Building ‘oranged’ to stop violence against women
Eliminate violence against women. That is the message of the Orange the World campaign. Leiden University is joining in this year, hence the ‘oranged’ Academy Building and Oude UB.
-
FvD politican Gideon van Meijeren in court for inciting violence
The Netherlands Public Prosecution Service has demanded that Gideon van Meijeren, Dutch Member of Parliament in the Forum for Democracy (FvD) party, be handed 200 hours of community service for inciting violence. Marloes van Noorloos, Associate Professor of Criminal Law, discusses when a comment turns…
-
From Descriptive to Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
-
Leiden University signs Amnesty manifesto against sexual violence
Leiden University signed the Amnesty International ‘Let’s talk about YES’ manifesto on 10 March, confirming the university’s commitment to preventing sexual violence. Steps will also be taken to make sure that everyone within the university feels responsible for a culture in which sex is based on equality…
-
market needs: new course for master’s students focuses on quality in drug development
Immediately connect with the needs of industry with your master’s degree. The new course Practical Aspects of Quality Management in Pharma and Biotech provides just that. The LACDR and LUMC set up the course together with the Biotech Training Facility, located at the Leiden Bio Science Park. The first…
-
NMR Facility
Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…
-
From scientific idea to promising new drug
Many pharmaceutical companies no longer have their own lab and are working more closely with universities and start-ups of scientists. Professor of Science-Based Business Simcha Jong is researching how scientific ideas result in new drugs, including at the Leiden Bio Science Park (LBSP).
-
Career Foreign Fighters: Expertise Transmission Across Insurgencies
Jeanine de Roy van Zuijdewijn, Chelsea Daymon and David Malet, wrote RESOLVE Network Research Report that examines career foreign fighters who have traversed from one insurgency to another.
-
Drone imagery in Islamic State propaganda: flying like a state
This article provides a comprehensive analysis of the Islamic State's use of images taken by drones, drawing on a dataset of ISIS propaganda images from October 2016 to December 2018.
-
Leiden based research confirms systematic and excessive violence in Indonesia
New research has confirmed that the Dutch military used systematic, extreme violence against Indonesians. In his book Soldaat in Indonesië (Soldier in Indonesia), to be released at the end of October, historian Gert Oostindie draws the same conclusions using different sources. He presents new findings…
-
Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
-
Parameter optimization toward optimal microneedle-based dermal vaccination
Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.
-
ZonMw grant for research on domestic violence family treatment
Although domestic violence often affects multiple family members, parents and children are usually treated separately for their traumatic experiences. In collaboration with women's shelter Rosa Manus, forensic partner the Waag, the municipality of Leiden and their colleagues from LUBEC (Leiden University…
-
Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
- Blog Posts
-
Cells with stress: predicting drug-induced liver and kidney damage
How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.
-
Laura Heitman
Science
l.h.heitman@lacdr.leidenuniv.nl | +31 71 527 4558
-
The Mesoamerican codex re-entangled: Production, use, and re-use of precolonial documents
This dissertation is concerned with the study of the less than twenty remaining precolonial Mesoamerican codices. By considering these rare and fragile pictographic and hieroglyphic books from the cultural biography perspective, many different aspects of these books can be studied.
-
Juan Masullo Jimenez
Faculteit der Sociale Wetenschappen
j.masullo@fsw.leidenuniv.nl | +31 70 800 3879
-
Professor Mariëlle Bruning elected Member of the Expert Group Violence Against Children of the Council of Europe (2018-2019)
Mariëlle Bruning, Professor of Child Law, is elected Member of the Expert Group on Responses to violence against children (CAHENF-VAC), which is established to assist the Ad hoc Committee for the Rights of the Child (CAHENF) of the Council of Europe.
-
De Witte et al publish in Nature Drug Discovery Reviews
Nature Reviews Drug Discovery volume 18, pages 82–84 (2019). The implications of target saturation for the use of drug–target residence time Wilbert de Witte, Meindert Danhof, Piet van der Graaf, and Elizabeth de Lange
-
INSIGHT: focus on the way in which firearms are related to firearms violence
The European Commission awarded the project proposal INSIGHT, a follow-up project on illegal firearms trafficking and gun violence from Professor Social Resilience and Security Marieke Liem and PhD-researcher Katharina Krüsselmann of the Institute of Security and Global Affairs (ISGA).
-
The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…
-
Drug discovery 3.0: more effective and humane
Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.
-
Impurities in sugar excipients could cause drugs to fail
Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.
-
Discovery of antibiotics and their targets in multidrug-resistant bacteria
Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.
-
Gut-on-chip good predictor of drug side-effects
Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.
-
Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
-
Mathematical model predicts drug concentration in the brain
Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…
-
Drug development: how can we make it more efficient?
It takes years to develop new medicines, from the test tube to trials in humans. During the process it often happens that a drug that seems promising in the initial stage has to be dropped in a later phase. This costs time and money. Leiden University and the LUMC are working closely together to make…
-
New project uses artificial intelligence in drug development
In health care, artificial intelligence is quite normal: it is used, for example, as an aid in making diagnoses. However, artificial intelligence is not yet used as much in drug development. A new prestigious partnership is therefore going to investigate how artificial intelligence can contribute to…