Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

Promotores: Wim Jiskoot; Ferry Ossendorp

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Promotores: W. Jiskoot, F. Ossendorp

We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.

The Center for Interdisciplinary Placebo Studies Leiden (IPS) aims to advance the understanding of placebo and nocebo effects, their underlying mechanisms, and their potential applications in clinical practice. IPS consists of a group of interdisciplinary researchers working at Leiden University with…

Why do flowers often smell so wonderful? And some other plants are very horrible? Come smell it, see it and discover it in the visitor center in the Old Observatory. Suitable for young and old.

The Lorentz Center organises public events with lectures by internationally renowned scientists.

The Resilience Center Leiden investigates how stress impacts the mental health of young people. For that, the team studies a multitude of factors, such as childhood experiences, the social environment, psychological factors, and neurobiological factors. With this multidimensional approach, we aim to…

The Leiden Healthy Society Center is a joint initiative between Leiden University's Faculty of Social and Behavioural Sciences and Leiden Municipality.

Sport Data Center

In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.

Leiden is part of the worldwide network of research centres dedicated to the research of Austrian Studies.

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

The facility develops and applies advanced, high-throughput methods for genomic research.

Researchers from Leiden University Medical Center (LUMC) and Netherlands Cancer Institute (NKI) have discovered how specialised immune cells can detect and remove cancers that are ‘invisible’ to the conventional defence mechanisms of the immune system. Their work has been published in Nature. The findings…

Developments in globalization and industrialization continuously push governments, international organizations and NGOs to reexamine the opportunities available to people at all levels of society to attain basic socioeconomic necessities. Research into existing social justice initiatives has shown a…

The Leiden University Center for Statistical Science unites the statisticians teaching and researching at Leiden University.

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

Explaining the origins , patterns and outcomes of crisis management efforts.

The Center studies the social, legal and normative impact of emerging digital technologies.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

The Leiden Center for the Study of Ancient Arabia aims to promote research on the ancient languages and cultures of Arabia, and to disseminate this knowledge to the broader public.

TRIXY is a national Center of Expertise, in which clinical professionals and expert researchers work together to improve knowledge and clinical care for children with X and Y chromosome trisomies.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

Impressions by Oene de Haan - PhD candidate at Utrecht University.

Behrouz Karoubi defended his thesis on 15 June 2016

Promotores: J. Jonkers, K.E. de Visser

Science, Leiden Institute of Advanced Computer Science (LIACS)

Impressions by Dr. Lilian Ruhe

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…

Impressions by Oene de Haan - PhD candidate at Utrecht University

The immune system plays a paradoxical role in the spread of breast cancer. Some immune cells contribute to metastasis, while other cells can be activated to strengthen the effect of chemotherapy. Kelly Kersten made this discovery in her PhD research. PhD defence 7 February.

Sport Data Center

The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.

PhD defence

Universiteit Leiden in cooperation with Naturalis, the University of Amsterdam (UvA) and University Wageningen is foundig a center for biodiversity. They will receive 30 million euros from The Ministry of Education, Culture and Science (OCW).

PhD defence

Professor Annemarie Meijer and several students explained to more than 8000 visitors the zebrafish as a model for research during the National Weekend of Science (3-4 Oct) at Science Center NEMO in Amsterdam.

One of the highlights during the fieldwork in Schoningen lead by Prof. dr. Thijs van Kolfschoten in 2013 was the opening of the museum and research center paläon on June 24. To the realisation of the museum, the Faculty of Archaeology made ​​a significant contribution. Many of the results of the research…

This joint Master with the Autonomous University of Barcelona will the equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. The programme includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy, and…

The Lorentz Center is a melting pot that is visited by researchers from around the world. ‘Miracles happen’ during the five-day interactive workshops at the Center. And there is an extra reason to celebrate the center’s 25th anniversary. On 28 April, the Dutch Research Council (NWO) and Leiden University…

PhD defence

PhD defence