The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…

Online Convex Optimization for the Effective Curvature

We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.

On 1 October 2019, Emile Cammeraat defended his thesis 'Economic Effects of Social Protection'. The doctoral research was supervised by Prof. K.P. Goudswaard and Prof. P.W.C. Koning.

More than half of Europeans speak two or more languages. Linguist Lisa Cheng investigates the various forms of multilingualism in Europe from a linguistic, cognitive and sociological perspective. She looks for instance at the way in which minority languages influence the standard language of a country,…

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Promotor: R. Tijdeman

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

This study is the first to directly relate brain development to sex differences and school performance. The results debunk the myth that brain development is slower in boys.

The Role and Effectiveness of the G20. In this article, published in The Changing Global Order part of the United Nations University Series on Regionalism book series, author Jaroslaw Kantorowicz discusses the evolution of the G20.

How do different emotional expressions influence the behavior of other people in negotiations?

Artful Mathematics: The Heritage of M. C. Escher

Simona Demková, Assistant professor at the Europa Institute of Leiden University, publishes her book ‘Automated Decision-Making and Effective Remedies: The New Dynamics in the Protection of EU Fundamental Rights in the Area of Freedom, Security and Justice’.

The Zmapp medicine has been developed with funding from the US government within the framework of the Small Business Innovation Research programme. The European Commission tried to emulate the success of this programme within the EU. Has its effort been adequate and sufficient? Is procurement of research…

Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

What are interactive effects of human pressures on aquatic communities?

De Nederlandse geschiedenis is nauw verbonden met die van de wereld als geheel. Door migratie, handel en kennisuitwisseling beïnvloedden mensen elkaar over grotere afstanden en intensiever dan we lang dachten. Wereldgeschiedenis van Nederland toonde in meer dan honderd verhalen hoe internationaal de…

Promotor: Prof.dr. A. Achucarro, Co-Promotor: J.W. van Holten

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

What role play stress and fear in forming of nocebo hyperalgesia?

Description of Effects of glufosinate-ammonium on off crop vegetation.

Promotor: P.M. Brakefield

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Drawing on insights from past and contemporary scholars and world leaders, the report explores the concepts of a new social contract, a new global deal, and networked and inclusive multilateralism introduced recently by Secretary-General António Guterres to help the United Nations better grapple with…

Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

Child homicide is a phenomenon that not infrequently leads to shock and societal unrest. However, the precise nature and scope of child homicide in the Netherlands remains unknown.

We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?

On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

This project seeks to integrate scientific research and practical knowledge in the study of the mechanisms that make dialogue an effective tool for communication, teaching, and thinking.

What is the effectiveness of two school-based skills-training programs in promoting mental health?

Can excessive worrying be reduced via stimulation of the vagus nerve?

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.

Promotor: Prof.dr.ir. J.W.M. Hilgenkamp, Prof.dr. J. van den Brink

The organisations and people who implement government policy face many different types of change. Academics from Leiden University research how they deal with these and advise them on how best to meet the needs and wishes of society.

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

To what extent did The Netherlands' attitude towards European integration change after the 2005 referendum on the European Constitution?