517 search results for “lipid chris leon” in the Public website
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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Superstructures of lipids and graphene
This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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Chris Peters
Science
c.a.m.peters@math.leidenuniv.nl | +31 71 527 2727
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Chris Deben
Bestuursbureau
c.p.j.deben@bb.leidenuniv.nl | +31 71 527 0000
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Chris Spaans
ICT Shared Service Centre
c.spaans@issc.leidenuniv.nl | +31 71 527 2727
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Chris Johnson
Faculteit Rechtsgeleerdheid
c.d.johnson@law.leidenuniv.nl | +31 71 527 2727
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Chris Staalman
Faculty of Humanities
c.r.staalman@hum.leidenuniv.nl | +31 71 527 2727
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Chris Neitzel
Universitair Facilitair Bedrijf
c.a.neitzel@ufb.leidenuniv.nl | +31 71 527 2727
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Chris Müller
ICT Shared Service Centre
c.h.muller@issc.leidenuniv.nl |
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Chris Handy
Faculty of Humanities
c.a.handy@hum.leidenuniv.nl | +31 71 527 2727
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Chris Suijker
Expertisecentrum Vastgoed
c.suijker@vastgoed.leidenuniv.nl | +31 71 527 7967
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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Leon Raabe
Science
raabe@physics.leidenuniv.nl | +31 71 527 8405
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Leon Chang
ICT Shared Service Centre
f.s.chang@issc.leidenuniv.nl | +31 71 527 7116
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Leon Aarts
Faculteit Geneeskunde
l.p.h.j.aarts@lumc.nl | +31 71 526 6046
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Leon Beeke
Science
l.p.beeke@science.leidenuniv.nl | +31 71 527 3640
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Leon Kleinveld
Faculty of Humanities
l.d.kleinveld@hum.leidenuniv.nl | +31 71 527 2727
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Leon Helwerda
Science
l.s.helwerda@liacs.leidenuniv.nl | +31 71 527 4799
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Leon Hilbert
Faculteit der Sociale Wetenschappen
l.p.hilbert@fsw.leidenuniv.nl | +31 71 527 2727
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Chris Verhoeven
Faculteit der Sociale Wetenschappen
verhoeven@fsw.leidenuniv.nl | +31 71 527 4069
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Chris Riddell
Faculteit der Sociale Wetenschappen
c.d.riddell@fsw.leidenuniv.nl | +31 71 527 2727
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Chris Hoeboer
Faculteit der Sociale Wetenschappen
c.m.hoeboer@fsw.leidenuniv.nl | +31 71 527 2727
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Phase behavior of skin lipid mixtures: the effect of cholesterol on lipid organization
The lipid matrix in the stratum corneum (SC), the upper layer of the skin, plays a critical role in the skin barrier. The matrix consists of ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs).
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The important role of stratum corneum lipids for the cutaneous barrier function
The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).
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Chris Flinterman
Faculty of Humanities
c.h.f.flinterman@hum.leidenuniv.nl | +31 71 527 6713
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Léon Buskens
Faculty of Humanities
l.p.h.m.buskens@hum.leidenuniv.nl | 212 53 76 68500
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Modulation of Stratum Corneum Lipid Composition and Organization of Human Skin Equivalents by Specific Medium Supplements
Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…
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Lipid signaling in brain diseases
Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].
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Cutaneous barrier dysfunction in atopic eczema: the role of stratum corneum lipids
Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 148-148 (2015) ISBN: 0142-5463
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Leon van der Drift
Universitair Facilitair Bedrijf
l.w.van.der.drift@ufb.leidenuniv.nl | +31 70 800 9512
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Leon Lapa Pereira
Faculty of Humanities
a.l.lapa.pereira@hum.leidenuniv.nl | +31 71 527 2727
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Léon de Roode
Expertisecentrum Vastgoed
la.deroode@vastgoed.leidenuniv.nl | +31 71 527 1194
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Human epidermal lipid biosynthesis in health and disease
How are the epidermal lipid pathways involved in health and disease.
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Human skin equivalents: understanding the lipid biosynthesis in the skin
There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.
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César Valenzuela León
Faculty of Humanities
c.f.valenzuela.leon@hum.leidenuniv.nl | +31 71 527 2125
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mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
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Chris van Oostrum
Faculteit Rechtsgeleerdheid
c.h.a.van.oostrum@law.leidenuniv.nl | +31 71 527 8915
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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ceramide chain length distribution on the barrier properties of the skin lipid membranes
The skin barrier function is provided by the stratum corneum (SC). The lipids in the SC are composed of three lipid classes: ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs) which form two crystalline lamellar structures. In the present study, we investigate the effect of CER chain length…
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Mette Léons
Faculteit Rechtsgeleerdheid
m.k.c.leons@law.leidenuniv.nl | +31 71 527 4852
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Towards artificial photosynthesis on the lipid bilayer of liposomes
Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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Lipid chain length reduction correlates with the skin barrier function in atopic eczema patients and inflammation plays a role in the altered
Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)
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distribution affects permeability barrier function of stratum corneum lipid model membranes
Source: International Journal of Cosmetic Science, Volume 37, Number 1, pp. 158-158 (2015) ISBN: 0142-5463