1,858 search results for “mexican drug violence” in the Public website
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Developing drugs with artificial intelligence
Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.
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Firearms and violence in Europe–A systematic review
Firearms and violence in Europe–A systematic review by Katharina Krüsselmann, Pauline Aarten, Marieke Liem
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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The reconstruction of the codex Añute palimpsest using hyperspectral imaging data
A technique originally developed for satellite imaging can now be used to recover pictographic texts from underneath the surface of a five hundred year old Mexican manuscript.
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the pharmacokinetics and pharmacodynamics of routinely used off-label drugs in premature neonates
Currently, more than 80% of drugs are used in an off-label manner in critically ill neonates.
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Focus on kinetics for better drug development
Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…
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Rethinking drug discovery: Vidi grant for Laura Heitman
Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.
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Peter Bouwman
Science
r.j.p.bouwman@lacdr.leidenuniv.nl | +31 71 527 6105
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Various media on drug research Mario van der Stelt
Media in the Netherlands and abroad reported extensively about the drug research led by Leiden chemist Mario van der Stelt. In this research, Van der Stelt shows which unwanted side-effects a French drug candidate has.
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New potential drug suppresses chemotherapy induced neuropathic pain
Oncode Investigator Mario van der Stelt and his colleagues have discovered a new potential drug that suppresses chemotherapy induced neuropathic pain.
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GTGC lunch seminar: Santino Regilme on Global Drug Wars
On the 6th of March 2023, Santino Regilme presented his work-in-progress titled 'Global Drug Wars: Contested Normative Orders of Peace, Security, and Human Rights'. If the battle against illegal drugs is construed as a war, how is victory in such a war defined and constructed? If the oppositional…
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How do children's kidneys eliminate drugs?
What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…
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Finding unique drug structures with artificial intelligence and chemistry
In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.
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Giulia Callegaro
Science
g.callegaro@lacdr.leidenuniv.nl | +31 71 527 6105
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New technique offers chemists unprecedented control in drug research
Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…
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Domestic Homicide
Behavioral Sciences Mental Health Psychological Disorders - Adult Aggression in Adults Psychological Science Social Psychology Criminology & Delinquency Social Sciences Criminology and Criminal Justice Crime and Crime Prevention Criminal Behaviour and Forensic Psychology Violent Crime Law Criminology…
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Marieke Liem
Faculty Governance and Global Affairs
m.c.a.liem@fgga.leidenuniv.nl | +31 70 800 9935
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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Drug Delivery to the Brain
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB
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Sabine van der Asdonk
Faculteit der Sociale Wetenschappen
s.van.der.asdonk@fsw.leidenuniv.nl | +31 71 527 5438
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Sheila van Berkel
Faculteit der Sociale Wetenschappen
berkelsvan@fsw.leidenuniv.nl | +31 71 527 6622
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Edmund Frettingham
Faculty Governance and Global Affairs
e.j.frettingham@luc.leidenuniv.nl | +31 70 800 9500
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Refugees, Perceived Threat & Domestic Terrorism
Refugees’ effect on domestic terrorism is conditioned by host-country social perception (attitude about living next-door to foreigners) and economic competition. These hypotheses are tested cross-nationally from 1995-2014 leveraging data from the World Values Survey.
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Firearm Homicides in Europe: A comparison with non-firearm homicides in five European countries
This paper presents the prevalence and characteristics of firearm homicides in Denmark, Finland, the Netherlands, Sweden and Switzerland
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More efficient drug development with the help of computer models
The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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Countering Violent Extremism - The International Deradicalization Agenda
This book presents an understanding of the concept of Countering Violent Extremism from a critical terrorism studies perspective using case studies from different countries while examining the issues it raises.
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In vivo tracking and biodistribution of protein aggregates
Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Bob van de Water
Science
water_b@lacdr.leidenuniv.nl | +31 71 527 6223
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Protecting Places of Worship in Europe: a Review of Literature and Future Research Trends
In this publication, May Tamimova and Tahir Abbas researched the existing literature about violence and hatred against places of worship.
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New measuring method facilitates drug research
Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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About this minor
Urban riots, violent responses by police, drug-related assassinations, child abuse, bar fights: Violence is a core theme in today’s modern society.
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Drugging the undruggable: NWO Open Competition grant for Alireza Mashaghi
Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Proving discriminatory violence at the European Court of Human Rights
On Tuesday 23 May 2017, Jasmina Mackic will defend her doctoral thesis ‘Proving discriminatory violence at the European Court of Human Rights’. The defence will start at 15.00 hrs, at the Academy Building of Leiden University, Rapenburg 73. The supervisor of the research is Vice Dean and Professor of…
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Academy Building ‘oranged’ to stop violence against women
Eliminate violence against women. That is the message of the Orange the World campaign. Leiden University is joining in this year, hence the ‘oranged’ Academy Building and Oude UB.
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From Descriptive to Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
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market needs: new course for master’s students focuses on quality in drug development
Immediately connect with the needs of industry with your master’s degree. The new course Practical Aspects of Quality Management in Pharma and Biotech provides just that. The LACDR and LUMC set up the course together with the Biotech Training Facility, located at the Leiden Bio Science Park. The first…
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NMR Facility
Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Leiden based research confirms systematic and excessive violence in Indonesia
New research has confirmed that the Dutch military used systematic, extreme violence against Indonesians. In his book Soldaat in Indonesië (Soldier in Indonesia), to be released at the end of October, historian Gert Oostindie draws the same conclusions using different sources. He presents new findings…
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Parameter optimization toward optimal microneedle-based dermal vaccination
Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.
- Blog Posts
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Career Foreign Fighters: Expertise Transmission Across Insurgencies
Jeanine de Roy van Zuijdewijn, Chelsea Daymon and David Malet, wrote RESOLVE Network Research Report that examines career foreign fighters who have traversed from one insurgency to another.
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Drone imagery in Islamic State propaganda: flying like a state
This article provides a comprehensive analysis of the Islamic State's use of images taken by drones, drawing on a dataset of ISIS propaganda images from October 2016 to December 2018.
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ZonMw grant for research on domestic violence family treatment
Although domestic violence often affects multiple family members, parents and children are usually treated separately for their traumatic experiences. In collaboration with women's shelter Rosa Manus, forensic partner the Waag, the municipality of Leiden and their colleagues from LUBEC (Leiden University…
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Cells with stress: predicting drug-induced liver and kidney damage
How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.