130 search results for “dna” in the Staff website
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Bart Custers on DNA in cold cases
The Dutch Public Prosecution Service (OM) and the Netherlands Forensic Institute (NFI) want to use private DNA databases in an effort to solve deadlocked murder cases. Bart Custers, Professor of Law & Data Science at eLaw, Center for Law and Digital Technologies, expects that this is permissible from…
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Bart Custers on using genealogical DNA in criminal cases
The Public Prosecutor's Office (OM) and the Netherlands Forensic Institute (NFI) want to use private DNA databases for genealogical research in criminal investigations. The method could be used in serious criminal cases that have stalled and it is already being used in investigations abroad. Whether…
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Bacteria without cell wall gobble up DNA from environment
A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…
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Ethical guidelines to better regulate DNA research on human remains
Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…
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‘Data science has crept into the faculties’ DNA’
From 14 to 29 PhD candidates, seven actively involved faculties and, above all, lots of innovative interdisciplinary research, all with data science as the common denominator. The university’s Data Science Research Programme (DSO) has proven so successful that after five years on a start-up grant it…
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Daniel Zumel Gete
Science
d.zumel.gete@cml.leidenuniv.nl | +31 71 527 2727
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Kaushar Kagzi
Science
k.kagzi@cml.leidenuniv.nl | +31 71 527 2727
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Kevin Groen
Science
k.groen@cml.leidenuniv.nl | +31 71 527 6822
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Sam Boerlijst
Science
s.p.boerlijst@cml.leidenuniv.nl | +31 71 527 2727
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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New method for extracting human DNA from archaeological objects yields success
An international team of researchers led by Leiden archaeology professor Marie Soressi and Leipzig senior geneticist Matthias Meyer has recovered the DNA of a woman belonging to an Ancient North Eurasian population from a 20,000-year-old pendant. This is the first time DNA analysis has been used to…
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Ancient DNA study reveals large scale migrations into Bronze Age Britain
A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.
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innovative research presenting a new method for recovering ancient human DNA
Since the publication of the article in the interdisciplinary journal Nature, over 200 news outlets have showcased the pioneering research.
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DNA analysis of historical mosquitoes will help us understand malaria transmission
Researchers from Leiden University, McMaster University and Public Health Ontario are calling on colleagues to track down archival specimens of mosquitoes from museums and other collections and to examine them with modern methods. This will tell them more about malaria transmission.
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Executive Board column: Our institutes abroad are part of our international DNA
Ever since its foundation, Leiden University has turned its gaze outwards to other cultures, languages and forms of academic practice. It is only natural, therefore, that we as a university have four institutes abroad: the Royal Netherlands Institute of Southeast Asian and Caribbean Studies (KITLV-KNAW)…
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3 October University: from Russian DNA to drug-related violence
In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…
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Jac Aarts
Faculteit Archeologie
j.m.m.j.g.aarts@arch.leidenuniv.nl | +31 71 527 2727
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Louie Krol
Science
l.krol@cml.leidenuniv.nl | +31 71 527 2727
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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DNA from a cup of pond water can reveal a lot: Kat Stewart will find out with a Vidi grant from NWO
She has had the idea for seven years, but now environmental scientist and conservation biologist Kat Stewart finally gets to work on it. She has been awarded a Vidi grant by NWO to find out how DNA from water can be used to shed light on invasive species and their impact on native populations.
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synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
PhD defence
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Emilie Didaskalou
Science
e.a.didaskalou@cml.leidenuniv.nl | +31 71 527 5652
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Meindert Lamers
Science
m.h.lamers@biology.leidenuniv.nl | +31 71 527 2727
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Oliver Tuazon
Faculteit Rechtsgeleerdheid
o.m.tuazon@law.leidenuniv.nl | +31 71 527 8838
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Kat Stewart
Science
k.a.stewart@cml.leidenuniv.nl | +31 71 527 2727
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Sylvia de Pater
Science
b.s.de.pater@biology.leidenuniv.nl | +31 71 527 4760
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First patient in the Netherlands successfully treated with stem cell gene therapy
Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…
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Leiden archaeologists mentioned in Top 13 Discoveries in Human Evolution during 2023
In a recent article published on PLOS, Drs. Briana Pobiner and Ryan McRae of the Smithsonian Institution National Museum of Natural History discuss the top 13 discoveries in human evolution in 2023.
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Paul Hooykaas
Science
p.j.j.hooykaas@biology.leidenuniv.nl | +31 71 527 4933
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‘Pharmacogenetics will become part of patient care’
Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’
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Caught in living cells: how bacteria regulate their genes to defend themselves
For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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How did Proto-Indo-European reach Asia?
Five thousand years before the common era (BCE), Proto-Indo-European, the mother of many languages that are spoken today in Europe, Central Asia and South Asia, originated in eastern Europe. PhD candidate Axel Palmér has combined a 175-year-old hypothesis with new techniques to demonstrate how descendants…
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Paco Barona Gomez ready to work in Leiden: ‘Fundamental research creates opportunities’
Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’
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Biology students expose exotic amphibians in the dunes
During the spring of 2021, a group of eight biology students from Leiden set out into the dunes in search of amphibians. Using DNA, they determined the geographic origin of the animals. And guess what? In many cases they discovered exotic populations of animals that do not naturally belong in The Netherlands.…
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‘Homo sapiens is too arrogant: call us Homo faber, the toolmaker’
We need to dispel the arrogant and misguided idea that modern humans are superior to earlier human species. It is thanks in part to all our predecessors such as Neanderthals that we are who we are today. This is what Marie Soressi, Professor of Hominin Diversity Archaeology, will argue in her inaugural…
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ERC Consolidator Grants for Leiden researchers
Five Leiden researchers have been awarded a Consolidator Grant by the European Research Council (ERC). This grant of up to two million euros will enable them to continue and expand their scientific research.
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New eDNA method opens doors for environmental research
With a single sample of water or soil, researches can analyse the DNA of everything that is living in that environment. During her research, PhD candidate Beilun Zhao discovered a way to analyse not only the kind of species, but also the age of the species in a water sample. The method showed its first…
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Campus Square renamed: Rosalind Franklin Square
On World DNA Day 25 April, Leiden University is pleased to focus the spotlight on Rosalind Franklin, whose name was given earlier this month to the Campus Square on the Leiden Bio Science Park. This square will now be known officially as the Rosalind Franklin Square.
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Vici grants for three Leiden researchers
Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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A first in the lab: a tiny network that is both strong and flexible
Daniela Kraft's group has succeeded in creating a network of microparticles that is both strong and completely flexible. This may sound simple, yet they are the first in the world to succeed in doing so. A real breakthrough in soft matter physics.
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Biology student Martijn Verkuilen wins Unilever Research Prize
Martijn Verkuilen is the winner of the Unilever Research Prize 2022. By transferring DNA from a plant into yeast, he made the first move to produce a new drug for type 2 diabetes. He collected his prize in Wageningen on 24 November.
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Vici grants for seven researchers from Leiden University
From research on stellar winds to sign language: an impressive seven researchers from Leiden University will receive a prestigious Vici grant from the Dutch Research Council (NWO).
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Making sustainable biotechnology a reality: joined forces aim to improve biocatalysts
Everything biobased: Plastic, medicine and fuel. It seems like a futuristic utopia. But for how long? A collaboration of researchers now proposes an idea to accelerate the development process. By combining machine learning and laboratory automation, this biobased ideal may become a reality rather sooner…
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Four Leiden researchers awarded Rubicon grants
Four promising young researchers will be able to conduct two years of research at a university abroad thanks to a Rubicon grant from the Dutch Research Council (NWO). The Leiden laureates are Renske Janssen, Girija Josh, Anne van der Meij and Yana van der Weegen.