1,139 search results for “diagnostics and treatment” in the Public website
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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The Vividness of Italian Baroque Sculpture between Literary Convention and Response
Subproject of
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Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
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Discriminatory allocation procedure for allotment gardens
The chairman of an allotment garden association in the Dutch town of Helmond has come under fire as its regulations contain a controversial rule that a maximum of five plots can be rented by one single nationality.
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Vision
The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.
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Vici grants for four Leiden researchers
Four Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Academic Research (NWO).
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Bioclock: Light therapy for depression
Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial
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Criteria for recovery from eating disorder patients: a comparison between therapists, patients and a healthy control group
Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?
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Quantitative Pharmacology
The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…
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Seven new Medical Delta professors
Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.
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Chronic subdural hematoma: tailoring treatment
PhD defence
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Clinical applications of (pharmaco)metabolomics
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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Strategy
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.
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Sybil-AA: Systems Biology of Alcohol Addiction
The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…
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Biorythm and brain dysfunction
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- Lectures
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Awards and Grants 2024
On this page you will find an overview of awards and prizes granted to our staff and students in 2024, as well as special appointments at Leiden University and other institutions.
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Internet-Based Treatment for Eating Disorders: Bridging the Treatment Gap
PhD defence
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Hypermarker
Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.
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High-Throughput Metabolomics
Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics
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After graduation
Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.
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Broadening the scope of the Social Resilience & Security programme: investigating suicide prevention skills and mental health of Ukraine refugees
The Social Resilience & Security interdisciplinary programme broadens its scope by embedding two research projects lead by Dr. Joanne Mouthaan. The projects adress suicide prevention skills and mental health of Ukraine refugees. Both projects will be integrated in the programme with the aim to improve…
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New professor fosters multidisciplinary approach to arthrosis
Arthrosis needs a multidisciplinary approach, says Professor Jaap Harlaar. He brings experts from different university medical centres together to unravel the secrets of this condition and thus improve its treatment. This new Medical Delta professor was appointed as Professor of Clinical Biomechanics…
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New professor wants to improve care for sarcoma patients
Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…
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The Power of Knowledge Ethical, Legal and Technological Aspects of Data Mining and Group Profiling in Epidemiology
With the rise of information and communication technologies, large amounts of data are being generated and stored in databases. In order to get a better grip on these large amounts of data, serious efforts are being made to discover patterns and relations in the data with the help of new techniques.…
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Astrochemistry and the Origin of Planetary Systems
Dishoeck
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Gradability in the nominal domain
This dissertation investigates whether and how gradability is manifested in the nominal domain, as well as the implications this could have for theories of the representation of gradability.
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The Archaeology of Greater Nicoya
Two Decades of Research in Nicaragua and Costa Rica
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.
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The Leiden University Old English ColloQuest
The Leiden University Old English ColloQuest is a digital, dynamic edition of an Old English text that adapts to each different learner to offer an appropriate level of challenge. The nature and number of glosses (translation aids) on the text adjust for each individual user based on the user’s answers…
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The recognition process of youth with problematic anxiety in general practice
Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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SFA of PVC in Sweden
In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).
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Challenged by cognition
Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome
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Efficacy of Self-management training in adolescents and adults with Klinefelter syndrome (XXY)
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New Medical Delta professors mean boost for health and technology research
Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.
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Medical Delta professor Andrea Evers: ‘I find it important to look for new ways’
Prof. Andrea Evers is a health psychologist who studies the role of behavioural factors in health and disease. As a Medical Delta Professor, she is now affiliated with Leiden University, TU Delft and Erasmus University. In that position, she conducts research at the intersection of various disciplines.…
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Early intervention in behavioural problems at school
Leiden University social scientists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.
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New Methods for (f)MRI Analysis
Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.
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Animal welfare
We carry a profound responsibility for our research animals and strive to provide them with the best possible quality of life. In our studies, we make every effort to avoid and minimise discomfort for the animals. Below, you can learn more about how this is put into practice.
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Laboratory for Artefact Studies
Commercial enterprises who want to make use of the expertise and facilities are referred to LAB , the commercial unit responsible for specialized laboratory work.
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Preventive Intervention Team
Leiden University neuropsychologists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.
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United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.
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Better screening can help GPs recognise anxiety disorders earlier
Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.
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Grants & Awards
Grants awarded to molecular physiology research