1,971 search results for “this week E2 80 99s discoveries” in the Public website
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Research
The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Drug Discovery & Safety and Systems Biomedicine and Pharmacology, and the Metabolomics and Analytics Centre.
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New discoveries by the Leiden-Turin excavations in Saqqara
Archaeologists from the National Museum of Antiquities (Leiden), the Museo Egizio (Turin, Italy) and Leiden University have found the grave of Panehsy, the 'steward of the temple of (the god) Amun', in Saqqara.
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Contact
Do you have questions about the Bio-Pharmaceutical Sciences master’s programme or the specialisation Drug Discovery and Safety? Please contact us.
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Erik Danen appointed as Professor of Cancer drug target discovery
As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.
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The archaeological discovery at the Paardenmarkt in Alkmaar
In the summer of 2010, a special archaeological find resurfaced when plans to redevelop the Paardenmarkt, a parking lot in the historic city center of Alkmaar, began.
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First discovery of high-energy neutrino source
For the first time, scientists have traced back a high-energy neutrino to its source in space. It was produced by a so-called blazar—a supermassive black hole. Researchers from neutrino detector IceCube report this in Science. ‘This is a milestone for neutrino science,’ says physicist Dorothea Samtleben…
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Freek Vonk gets his own show on Discovery Channel
Biologist Freek Vonk had already appeared in the Time Warp programme, where he was shown milking a snake for its venom, which he needed for his doctoral research. On Friday 18 September, he explained his fascination for snakes to Matthijs van Nieuwkerk in ‘De wereld draait door’, a Dutch news and entertainment…
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi
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NMR structural studies of protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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International orientation week: don’t miss it!
Welcome to Leiden and The Hague! So there you are, an international BA or MA student, in a city where you don’t know the way and don’t speak the language. What now? Don’t panic: with our international introduction programmes, you’ll soon have learnt all the ins and outs. And another important thing:…
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Alumnus Robert Ietswaart: ‘Machine learning is revolutionising drug discovery’
Robert Ietswaart does research into gene regulation at the famous Harvard Medical School in Boston. He developed an algorithm to better predict whether a candidate medicine is going to produce side effects. He studied mathematics and physics in Leiden, and gained his PhD in computational biology in…
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A week immersed in solar biofuels
The Honours Class From Solar to Fuel with Bio consisted almost entirely of the workshop on Solar Biofuels from Micro-organisms that drew more than eighty specialist researchers to Leiden's Lorentz Centre in late March/early April. Students Erica Wenker (chemistry) and Jasper van Dobben de Bruijn (law)…
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LUC The Hague Introduction Week 2020
The logistics and organisation of LUC’s introduction week 2020 were put under the spotlight this year in light of the restrictions which remain in place with respect to COVID-19. In the face of adversity, LUC rose to the challenge and met the learning curve with patience, dedication and resilience.
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Will this discovery help us develop better catalysts?
Where exactly on the surface of a catalyst do the chemical reactions occur? Until now, it has always been a challenge to identify the exact locations of these ‘active sites’. In a new article in Nature, Leiden chemists helped their international colleagues reveal new insights into this issue. Their…
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PhD Research || Re-discovery of the Italian salterio
It was her original Salterio from 1725, built by Michele Barbi, which Franziska Fleischanderl could coincidentally acquire in 2014 that ignited her passion for this special string instrument. Before, she was focussed on contemporary music with modern Hackbrett.
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Final weeks: Above and Beyond
January is the final month of our temporary exhibition 'Above and Beyond: Making Sense of the Universe for 100 Years'. You can visit every weekend until Jauary 26th.
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Astronomer Joe Callingham testifies against killer stars in new show on Discovery Channel
On Friday evening 17 September, Leiden astronomer Joe Callingham can be seen in a new series on Discovery channel. Killers of the Cosmos is about different deadly dangers lurking in the depths of space. Asteroids, cosmic debris, electromagnetic weapons… The show takes a film-noir approach to these threats,…
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Singing & Music
The Leiden Academic Course Center offers a large variety of short and longer music courses. The music category includes various Singing courses, but also courses such as Private guitar lessons and Musical. A number of courses are offered at different levels. Singing basics course is suitable for complete…
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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In pictures: kick-off Healthy University Week
On Monday 28 October, we celebrated the start of Healthy University Week 2019. During this week, students and staff of Leiden University can follow workshops to help them adopt a healthier lifestyle.
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Proteochemometrics
Research question
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Discovery of a unique silver bowl from the Early Middle Ages
On an excavation site in Oegstgeest Leiden University archaeologists discovered a very rare silver bowl from the first half of the seventh century. The bowl is decorated with gold-plated representations of animals and plants and inlaid with semi-precious stones. The discovery suggests the existence…
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Anthe Janssen
Science
a.p.a.janssen@lic.leidenuniv.nl | +31 71 527 4362
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
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Flurry of new discoveries as incredible new image revealing 4.4 million galaxies is made public
Over a seven year period an international team of scientists has mapped more than a quarter of the northern sky using the Low Frequency Array (LOFAR), a pan-European radio telescope. From Leiden, Astronomer Timothy Shimwell and Huub Röttgering, among others, are involved. It reveals an astonishingly…
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Registration open for introduction weeks: what to expect
Will you be coming to study at our university? If so, we want you to feel welcome. We therefore offer three different introduction weeks, with something for everyone: one in Leiden, one in The Hague and one for internationals. Register soon!
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Sebastian Pomplun
Science
s.j.pomplun@lacdr.leidenuniv.nl | +31 71 527 4651
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How EL CID week can go ahead after all
When the government introduced its corona measures, the future of EL CID suddenly looked uncertain. But this annual introduction week will start on 5 August after all. How did the EL CID board pull this off? A glimpse behind the scenes through the eyes of chair Mirte Haanappel.
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Research
Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.
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AiChemist project
The AiChemist project (https://aichemist.eu) coordinated by Helmholtz Munich is an Innovative Doctoral Training Network funded through the Marie Skłodowska-Curie Actions (MSCA-DN) within the EU Horizon Research Framework, to the sum of €3 million. It brings together leading experts in AI, chemoinformatics…
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Minister Dijkgraaf visits OWL international introduction week
On Monday, Minister of Education, Culture and Science Robbert Dijkgraaf attended the start of Orientation Week Leiden (OWL), the introduction week for international students at Leiden University. He welcomed the students and spoke with them about their ambitions and the problems they face.
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Record number of international students join introduction week
From Afghanistan to South Africa: 1,144 international students, including refugees from Syria, are taking part in the Orientation Week Leiden.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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National Week without Meat
National Week Withouth Meat: March 9th-15th @ Leiden University PURE restaurants
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Postponement of the Congress on the Social Benefits of Higher Education to the autumn
The organising committee of the congress 'Social Benefits of Higher Education' has decided to postpone the congress.
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Week Zonder Vlees
Nationale Week Zonder Vlees is een landelijke campagne en wordt breed gedragen door diverse partners uit de voedselindustrie!⠀
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No classes and working from home: here’s what our week looked like
From the new Hortus botanicus podcast to conference call bingo: all the students, lecturers and other members of staff from Leiden University had to switch at breakneck speed to working and studying from home this week. That meant decluttering offices, getting your head around remote teaching and installing…
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Make your choice! Three introduction weeks for students at Leiden University
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new students at Leiden University can best choose: EL CID, HOP or OWL.
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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First discovery of methanol in a warm planet-forming disk
An international team of researchers led by Alice Booth (Leiden University, the Netherlands) have discovered methanol in the warm part of a planet-forming disk. The methanol cannot have been produced there and must have originated in the cold gas clouds from which the star and the disk formed. Thus,…
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Robust rules for prediction and description.
In this work, we attempt to answer the question: