1,141 search results for “have screen” in the Public website
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Josephine van der Have
Faculteit Rechtsgeleerdheid
j.c.van.der.have@law.leidenuniv.nl | +31 71 527 7840
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Screening
Information about the extract library's facilities.
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High-throughput screening for developmental and reproductive toxicity
Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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Vertebrate automated screening technology (VAST)
How can you use robots and automatic recognition of microscopic images to test the effect of drugs exceptionally quickly?
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Screening of animal venoms for antimicrobial compounds
Can animal venoms yield novel antimicrobial peptides?
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Overcoming the Debye screening length with radiofrequency-operated graphene biosensors
Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Training network on zebrafish infection models for pharmaceutical screens
How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?
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automatic image analysis methods for high-throughput and high-content screening
Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek
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Xuesong Wang
Science
x.wang@lacdr.leidenuniv.nl | +31 71 527 6225
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer
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What is behind the screen? Object Individuation by 10 months old infants
Making sense of the world around us depends on the fundamental ability to parse the world into distinct objects and keep track of them. This process is defined as object individuation. Research indicates that it is not always easy for infants.
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Joanne Mouthaan
Faculteit der Sociale Wetenschappen
j.mouthaan@fsw.leidenuniv.nl | +31 71 527 6781
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Dominik Sieh
Faculteit der Sociale Wetenschappen
d.s.sieh@fsw.leidenuniv.nl | +31 71 527 7332
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A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits
Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Outage due to blue screen
After a Windows update, some HP laptops get a blue screen (Probook 430/450 G8). If you also experience this please contact the helpdesk (071 527 8888).
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Getting students away from screens... and into the landscape
Leiden University's International Honours College, Leiden University College The Hague (LUC) experienced empty halls and empty classrooms this past year on the residential campus on the Anna van Buerenplein in The Hague due to the global pandemic. Dr Paul Hudson designed a Covid-proof course that enabled…
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Shadow Game Screening with film maker Els van Driel
On 10 March students of the advanced master's in International Children’s Rights and the Dutch Child Law master's watched the documentary Shadow Game with filmmaker Els van Driel.
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Should the VOG screening process be extended to include administrative fines?
Research shows that including administrative fines in the screening process for a Certificate of Conduct (in Dutch: VOG) is not currently feasible.
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Screening enormous databases to find a cure for cancer
Pharmaceutical research should make more use of data science, says Gerard van Westen, postdoctoral fellow at the Leiden Academic Centre for Drug Research (LACDR). ‘If we want to have better drugs, we should start with data.’
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Film by CADS alumna Loes Moree screened at Field Recordings in Rotterdam
The film MعLMIN made by Visual Ethnography alumna Loes Moree will be screened during the fourth Fieldrecordings event. Field Recordings is an annual event for visual anthropology, sound art and landscape film.
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Better screening can help GPs recognise anxiety disorders earlier
Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.
- Extracts
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Unravelling cancer drug resistance mechanisms
Mechanisms fro drug resistance
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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The role of zebrafish (Danio rerio) larvae in developing new drug candidates for treating anxiety, from natural sources
Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?
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Topic: Self-management in chronic diseases
Having a chronic somatic condition can result in a variety of impairments in patients’ daily lives, including not only physical complaints such as pain, itch, and fatigue, but also problems of negative mood and impairments in social relationships. Next to disease characteristics, individual difference…
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History is a matter of a longing for rifles and flat screen TVs
History can be found in utensils and in interviews with ordinary citizens. ‘With the reconstruction of everyday life, an anthropological approach works better,’ thinks historian Jan-Bart Gewald. Inaugural lecture on 6 June.
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Glucocorticoid modulation of the immune response
Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein
Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: J.N. Kok, Co-promotor: F.J. Verbeek
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Aspects of cosmic acceleration
The focus of the dissertation
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Tailored care for children at high risk for problem behaviour
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Forensic Family and Youth Care Studies lab
Biological and behavioural measurements of parent-child interactions.
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Film Screening: Crip Camp
Arts and culture, Conference | D&I Symposium
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Silkscreening (every other week)
Arts and leisure, Arts and leisure
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
- Results
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal