2,392 search results for “mathematical and statistical modelling” in the Public website
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Terry Mostert
Faculteit der Sociale Wetenschappen
t.m.m.mostert@fsw.leidenuniv.nl | +31 71 527 2727
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and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Peter Grünwald professor statistical learning
As of November 1st, Peter Grünwald has been appointed professor Statistical learning on a new chair hosted by both the Mathematical Institute and the Leiden Institute for Advanced Computer Science (LIACS).
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Duality, bosonic particle systems and some exactly solvable models of non-equilibrium
Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander
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Minimal structure modeling
Existing work in probabilistic language modeling can be mostly divided into two categories:
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Biotic ligand models
Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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Education
The Mathematical Institute offers a bachelor programme in Mathematics and master programmes in Mathematics and in Statistical Science. The institute also teaches many mathematics and statistics courses in other academic programmes of the university. About 65 PhD students work on a thesis in a small…
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Bioactivity based quality control for Chinese herbal medicine
Can we establish a new quality control system for herbal medicines that is based on bioactivity rather than a few abundant chemicals?
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Strategic research into and development of best practice for, predictive modelling on behalf of Dutch Cultural Resource Management
Are predictive archaeological maps a reliable tool to play an important role in the spatial planning? One of the goals of this project was to develop best practices for the production and application of the models.
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The parabolic Anderson model on Galton-Watson trees
The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.
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Why Leiden University?
The Mathematics master’s programme will guarantee a thorough theoretical basis and will make sure you are ready to work in a multidisciplinary environment. Your mathematical degree will give you the right tools to operate successfully on the international market.
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Why Leiden University?
The Mathematics and SCS master specialisation gives you the opportunity to combine Mathematics research with different aspects of science communication.
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PhD: Modeling the mechanical regulation of plant development and regeneration (1.0 FTE)
Science, Mathematical Institute (MI)
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Why Leiden University?
The two-year research programme Applied Mathematics offers courses at an advanced level. There is a large degree of freedom in choosing one’s own topics. Some of the courses are given at national level, in the Dutch Mastermath programme. The programme concludes with the preparation of a master’s the…
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Postdoc Three-dimensional simulation models of plant tissue mechanobiology (1.0 FTE for three years)
Science, Mathematical Institute (MI)
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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PhD Competence Model
In 2016, Dutch University Medical Centres (UMCs) developed the self-evaluation tool based on the PhD Competence Model. Our partners at Utrecht University are making a digital version of the tool available free of charge for our PhD candidates at Leiden University, including for candidates who are not…
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Animal models for cutaneous vaccine delivery
Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska
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Data Science: Computer Science (MSc)
The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…
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Model painting with diverse techniques
Arts and leisure, Arts and leisure
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Why Leiden University?
Statistics & Data Science is highly multidisciplinary. Within the programme we offer you a unique combination of knowledge and expertise through close collaboration.
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Data Driven Modeling & Optimization of Industrial Processes
Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.
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Modelling metastatic melanoma in zebrafish
Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.
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Italian nurse acquitted of murder after statistical analysis
Italian nurse Daniela Poggiali was arrested and convicted of murdering two hospital patients in 2014. Her case attracted the attention of Leiden statistician Richard Gill. After his investigation, together with an Italian colleague, Poggiali was acquitted last autumn. Together with fellow statisticians,…
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Aad van der Vaart Scientific Director Mathematical Institute
Prof. dr. Aad van der Vaart has been appointed as Scientific Director of the Mathematical Institute of Leiden University on Tuesday 15 September 2015. He succeeds prof. dr. Peter Stevenhagen who has been a dedicated Scientific Director of the Mathematical Institute as from 2007.
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Why Leiden University?
The Algebra, Geometry and Number Theory specialisation gives you profound knowledge of pure mathematics. The focus is on both fundamental mathematics and on applications in other sciences, society and industry. During your master’s you will be part of one of the multidisciplinary research teams at the…
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Why Leiden University
The Mathematics and Education master specialisation gives you the opportunity to combine Mathematics research with an excellent education in becoming a Mathematics teacher.
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Ruben Huele
Science
huele@cml.leidenuniv.nl | +31 71 527 FLEX
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Why Leiden University?
Combine training in Mathematics research with different aspects of business studies. Learn to build bridges between science and business.
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Goodbye SPSS, hallo R: ‘Now we can help students who like statistics to excel’
After the summer, the SPSS statistics programme will be replaced by the new ‘R’ software for first year students. Hemmo Smit and Sjoerd Huisman, both lecturers in Methodology and Statistics, initiated this major change in the curriculum. That did not happen overnight.
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Stepwise latent class analysis
The main methodological aspects of the use of stepwise LCA estimators under different circumstances.
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An Ontology for Physical Necessity
The central inquiry of this thesis revolves around how ontology can adequately accommodate the existence of necessary physical relations. Initially, the thesis demonstrates the imperative acknowledgment of necessary physical relations by showcasing the failure of Neo-Humean theories.
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About us
The Mathematical Institute is one of the eight institutes of the Faculty of Science. The institute operates as a single unit defined by the activities of its members.
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Abstract delta modeling: software product lines and beyond
Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke
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Professor Richard Gill at TEDxFlanders “Statistical Errors in Court”
In a recent TEDx Flanders event “Statistical Errors in Court”, Statistical Scientist Richard Gill speaks about the case of Lucia de Berk, a nurse found guilty of several murders based largely on statistics.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Contact
You may contact LUXs through any of its members or secretariats of its participating institutes. You may also reach the steering group through its chair or secretariat.
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Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
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José Mogollón
Science
j.m.mogollon@cml.leidenuniv.nl | +31 71 527 7166
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Development of a Dynamic Substance Stock Model
Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.
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A mathematical model for a more diverse workforce
Many organisations have a biased workforce, even though diversity has so many advantages. Australian and Dutch researchers, including Leiden psychologist Romy van der Lee, have developed a solution based on a mathematical model. They published their findings in PLoS One on 28 July.
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Henk Kelderman
Faculteit der Sociale Wetenschappen
h.kelderman@fsw.leidenuniv.nl | +31 71 527 2727
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Record number of students in mathematics this year
The number of mathematics students in higher education is increasing spectacularly. This year, the influx of new students rises to more than 1000 on a national scale. This is a fivefold increase compared to the number of students that registered for an education in Mathematics in 2002.