1,486 search results for “human evolution” in the Public website
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Catecholamine function, brain state dynamics, and human cognition
The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.
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Benjamin’s Figures: Dialogues on the Vocation of the Humanities
The writings of Walter Benjamin (1892-1940) are famously and purposely marked by fragmentariness. Paradoxically, a central aim of his work was to connect: all his life he sought to further the integration of scholarship in the humanities which, he believed, had too long suffered from the prevalence…
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TERRA: TERraced landscape of RAmosch, Switzerland
This project investigates the well-preserved agricultural terraces of the Inn valley and the evolution of resource use in the inner Alps.
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Metals in the diffuse gas around high-redshift galaxies
Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)
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Child Marriage as a Choice. Rethinking agency in international human rights
On 18 March 2020, Hoko Horii defended her thesis ‘Child Marriage as a Choice. Rethinking agency in international human rights’. The doctoral research was supervised by prof. A.W. Bedner and prof. G.A. van Klinken.
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets
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Resolving a bioindicator diatom species complex using genomic approaches for freshwater biomonitoring
This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;
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Correcting each other’s mistakes - why cells stuck together in early evolution
The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…
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Case studies
The research that is united in the Liveable Planet programme, touches upon a wide range of aspects of human life. The goal is to deepen and expand the scope and to connect more researchers. The following case studies are examples of current research projects.
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cold: The adaptive role of pyrotechnology among the earliest modern humans in Europe, ca. 45,000–20,000 years ago
The routine assumption that Upper Palaeolithic early modern humans in Europe were regular fire users who produced fire at will has never been tested against the archaeological record. Utilizing literature, database and microwear analytical approaches, this project seeks to establish the role and forms…
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based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Human epidermal lipid biosynthesis in health and disease
How are the epidermal lipid pathways involved in health and disease.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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The right to family unification : between migration control and human rights
The central question in this book is whether there is a human right to family unification.
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COMET. Human Subject Research and Medical Ethics in Colonial Southeast Asia
Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.
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The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes
Venomous animals serve as models for a variety of mimicry types. Michael Richardson (IBL) and his international colleagues find that a group of fishes (called fangblennies) evolved venom after the origin of their venom-delivering fangs.
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Microbial hitchhiking
How do nonmotile microbes leverage communal motility?
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The characteristics of galaxies with powerful radio jets
Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.
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Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents
BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…
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Evolutionary traps – Balanced lethal systems
How do balanced lethal systems originate and persist in nature?
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How Bio-questionable are the Different Recombinant Human Erythropoietin Copy Products in Thailand?
The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market.
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Thijs van Kolfschoten
Faculteit Archeologie
t.van.kolfschoten@arch.leidenuniv.nl | +31 71 527 2640
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Willem Meilink
Science
w.r.m.meilink@biology.leidenuniv.nl | +31 71 527 4882
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Michael Richardson
Science
m.k.richardson@biology.leidenuniv.nl | +31 71 527 5215
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Vincent Niochet
Faculteit Archeologie
v.niochet@arch.leidenuniv.nl | +31 71 527 2727
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Comparative ecology and genetics of sympatric wild cats in relation to human wildlife conflict in Bardia National Park, Nepal
What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…
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DNAmarkerpoint
The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.
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Intracellular allosteric modulators for human CC chemokine receptors
Supervisor: Natalia Ortiz Zacarías
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Inter-Section: How Materials Shaped the Human World
The Faculty of Archaeology's own home-grown journal Inter-Section has released a new volume. Inter-Section offers students and PhD candidates the unique chance to publish in a peer-reviewed journal. The new volume focuses on the materials that shape our world.
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Julian Steinke
Faculteit der Sociale Wetenschappen
j.steinke@fsw.leidenuniv.nl | +31 71 527 2727
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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Integrative taxonomy of araneomorph spiders: Breathing new life into an old science
Taxonomy as a science has accumulated data and knowledge for more than 250 years.
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
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Bayesian Inference for Gaussian Models
This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.
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Artificial metallo-proteins for photocatalytic water splitting: stability and activity in artificial photosynthesis
Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Schöningen - Archaeozoological Research
The aim of the research project is to get insight in the biostratigraphical age and the palaeoecological setting of the Schöningen sites and hominin behavior and subsistence during the late Lower Palaeolithic.
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Mind the gap: gas and dust in planet-forming disks
Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
- Teaching Social Sciences and Humanities in Secondary Education (MA)
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The music of language: exploring grammar, prosody and rhythm perception in zebra finches and budgerigars
Promotor: C.J. ten Cate
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Education
Study Archaeology at Leiden University. Learn about a full range of theoretical, analytical and field methods from some of the world's leading archaeological researchers.
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Studying Homo erectus Lifestyle and Location (SHeLL)
An integrated geo-archaeological research of the hominin site Trinil on Java
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Human-lion conflict around Nairobi National Park: Lion Population Structure, Diet, and Movement in a Semi-Fenced Park.
What is the population size and social structure in time and space? What is the lion diet and food preference in time and space? What is the home range (MCP and Kernel) and movement in time and space? What are human – lion conflict and responses of lions to traditional herding in time and space? What…
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From Mimesis to Metaphor: Reconciling Nature and Humanity in the Age of Climate Crisis
Environmental humility is integral to addressing the climate crisis, but humility can also lead to political domination. How can humans relate to nature more humbly without risking domination?
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Dan Saxon
Faculty Governance and Global Affairs
d.r.saxon@luc.leidenuniv.nl | +31 70 800 9503
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Mélie Louys
Faculteit Archeologie
m.louys@arch.leidenuniv.nl | +31 71 527 NNB
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Femke Reidsma
Faculteit Archeologie
f.h.reidsma@arch.leidenuniv.nl | +31 71 527 1680