3,247 search results for “this week s discoveries” in the Public website
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Rethinking drug discovery: Vidi grant for Laura Heitman
Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.
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Three introduction weeks for Leiden University students. The choice is yours
Leiden or The Hague? Dutch or English? These two questions decide which introduction week new Leiden University students should choose: EL CID, HOP or OWL.
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Drug discovery 3.0: more effective and humane
Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.
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Three discoveries for cleaner and cheaper fuel
How can rare and expensive materials be used more efficiently to produce cleaner and cheaper fuel? Under the guidance of Marc Koper, Professor of Catalysis and Surface Chemistry, international teams of scientists have published 3 articles in Nature Communications.
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Leiden discovery leads to new ageing cream and chicken feed
What do a novel anti-ageing ingredient for cosmetics and a new type of chicken feed have in common? They were both produced using a new solvent developed by Leiden biologists in 2011. The medium is neither solid nor liquid, and the industry is now starting to see it’s many possibilities.
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Leiden discovery evaluated by world-leading breeding companies
Various companies in the plant biotech industry will test a recent Leiden discovery in their crops. The ‘Pol Theta’ technology is developed in Leiden and makes it possible to reduce undesired side effects during genome engineering of plants.
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De Witte et al publish in Nature Drug Discovery Reviews
Nature Reviews Drug Discovery volume 18, pages 82–84 (2019). The implications of target saturation for the use of drug–target residence time Wilbert de Witte, Meindert Danhof, Piet van der Graaf, and Elizabeth de Lange
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New discoveries by the Leiden-Turin excavations in Saqqara
Archaeologists from the National Museum of Antiquities (Leiden), the Museo Egizio (Turin, Italy) and Leiden University have found the grave of Panehsy, the 'steward of the temple of (the god) Amun', in Saqqara.
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Elizabeth (Liesbeth) de Lange
Science
ecmdelange@lacdr.leidenuniv.nl | +31 71 527 6330
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SAVE THE DATE: Open Science Week 2024 at the Faculty of Archaeology
Festival
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culture week fgga
culture week fgga. from 25 to 29 May we will pay extra attention to culture. A different theme is central every day.
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SAVE THE DATE: Open Science Week 2024 at the Faculty of Governance and Global Affairs
Festival
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Erik Danen appointed as Professor of Cancer drug target discovery
As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.
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The archaeological discovery at the Paardenmarkt in Alkmaar
In the summer of 2010, a special archaeological find resurfaced when plans to redevelop the Paardenmarkt, a parking lot in the historic city center of Alkmaar, began.
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First discovery of high-energy neutrino source
For the first time, scientists have traced back a high-energy neutrino to its source in space. It was produced by a so-called blazar—a supermassive black hole. Researchers from neutrino detector IceCube report this in Science. ‘This is a milestone for neutrino science,’ says physicist Dorothea Samtleben…
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Rehana Dole
Faculteit Rechtsgeleerdheid
n.r.s.dole@law.leidenuniv.nl | +31 71 527 2727
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Sofia de Jong
Faculteit Rechtsgeleerdheid
s.w.m.de.jong@law.leidenuniv.nl | +31 71 527 2727
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Nina van Capelleveen
Faculteit Rechtsgeleerdheid
n.u.van.capelleveen@law.leidenuniv.nl | +31 71 527 7607
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Marieke Baldee
Faculteit Rechtsgeleerdheid
m.h.baldee@law.leidenuniv.nl | +31 71 527 2727
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Marit Ruitenberg
Faculteit der Sociale Wetenschappen
m.f.l.ruitenberg@fsw.leidenuniv.nl | +31 71 527 2727
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Diana Davila Gordillo
Faculteit der Sociale Wetenschappen
d.l.davila.gordillo@fsw.leidenuniv.nl | +31 70 800 9500
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Freek Vonk gets his own show on Discovery Channel
Biologist Freek Vonk had already appeared in the Time Warp programme, where he was shown milking a snake for its venom, which he needed for his doctoral research. On Friday 18 September, he explained his fascination for snakes to Matthijs van Nieuwkerk in ‘De wereld draait door’, a Dutch news and entertainment…
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi
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NMR structural studies of protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Alumnus Robert Ietswaart: ‘Machine learning is revolutionising drug discovery’
Robert Ietswaart does research into gene regulation at the famous Harvard Medical School in Boston. He developed an algorithm to better predict whether a candidate medicine is going to produce side effects. He studied mathematics and physics in Leiden, and gained his PhD in computational biology in…
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Xi’an Jiaotong University Day at Leiden University
16 April was a special day at the Faculty of Science. In honour of the collaborations with the Chinese partner university, it was declared Xi’an Jiaotong University Day.
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Book ‘Darwin’s combination lock’ gives us hope
Former dean and physicist Frans Saris writes in his new book ‘Darwin’s combination lock’ how our culture enabled us to dominate nature and about the corresponding responsibilities. Together with Joris Berkhout he will talk about his book during the This Week’s Discoveries on 27 February.
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International orientation week: don’t miss it!
Welcome to Leiden and The Hague! So there you are, an international BA or MA student, in a city where you don’t know the way and don’t speak the language. What now? Don’t panic: with our international introduction programmes, you’ll soon have learnt all the ins and outs. And another important thing:…
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Will this discovery help us develop better catalysts?
Where exactly on the surface of a catalyst do the chemical reactions occur? Until now, it has always been a challenge to identify the exact locations of these ‘active sites’. In a new article in Nature, Leiden chemists helped their international colleagues reveal new insights into this issue. Their…
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A week immersed in solar biofuels
The Honours Class From Solar to Fuel with Bio consisted almost entirely of the workshop on Solar Biofuels from Micro-organisms that drew more than eighty specialist researchers to Leiden's Lorentz Centre in late March/early April. Students Erica Wenker (chemistry) and Jasper van Dobben de Bruijn (law)…
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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PhD Research || Re-discovery of the Italian salterio
It was her original Salterio from 1725, built by Michele Barbi, which Franziska Fleischanderl could coincidentally acquire in 2014 that ignited her passion for this special string instrument. Before, she was focussed on contemporary music with modern Hackbrett.
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LUC The Hague Introduction Week 2020
The logistics and organisation of LUC’s introduction week 2020 were put under the spotlight this year in light of the restrictions which remain in place with respect to COVID-19. In the face of adversity, LUC rose to the challenge and met the learning curve with patience, dedication and resilience.
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Astronomer Joe Callingham testifies against killer stars in new show on Discovery Channel
On Friday evening 17 September, Leiden astronomer Joe Callingham can be seen in a new series on Discovery channel. Killers of the Cosmos is about different deadly dangers lurking in the depths of space. Asteroids, cosmic debris, electromagnetic weapons… The show takes a film-noir approach to these threats,…
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Leiden archaeologists mentioned in Top 13 Discoveries in Human Evolution during 2023
In a recent article published on PLOS, Drs. Briana Pobiner and Ryan McRae of the Smithsonian Institution National Museum of Natural History discuss the top 13 discoveries in human evolution in 2023.
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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Final weeks: Above and Beyond
January is the final month of our temporary exhibition 'Above and Beyond: Making Sense of the Universe for 100 Years'. You can visit every weekend until Jauary 26th.
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Anthe Janssen
Science
a.p.a.janssen@lic.leidenuniv.nl | +31 71 527 4362
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Discovery of a unique silver bowl from the Early Middle Ages
On an excavation site in Oegstgeest Leiden University archaeologists discovered a very rare silver bowl from the first half of the seventh century. The bowl is decorated with gold-plated representations of animals and plants and inlaid with semi-precious stones. The discovery suggests the existence…
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Rob van Wijk discusses the role of zebrafish in drug discovery
Rob van Wijk gave an interview on the role of zebrafish in drug discovery and development, published in FIGON’s journal Medicines as a preview of LACDR’s representation at the PhD competition during the Dutch Medicines Days (DMD). The entire interview can be read below.
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Night of Discoveries: 3D-printed paintings and the effects of psychedelics
Come to the Night of Discoveries art and science festival on 16 September. Various researchers from the university are speaking at the festival.
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No classes and working from home: here’s what our week looked like
From the new Hortus botanicus podcast to conference call bingo: all the students, lecturers and other members of staff from Leiden University had to switch at breakneck speed to working and studying from home this week. That meant decluttering offices, getting your head around remote teaching and installing…
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In pictures: kick-off Healthy University Week
On Monday 28 October, we celebrated the start of Healthy University Week 2019. During this week, students and staff of Leiden University can follow workshops to help them adopt a healthier lifestyle.
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Master's application and admission
Find out how to apply for Drug Discovery and Safety at Leiden University by following our step-by-step guide.
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Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
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Flurry of new discoveries as incredible new image revealing 4.4 million galaxies is made public
Over a seven year period an international team of scientists has mapped more than a quarter of the northern sky using the Low Frequency Array (LOFAR), a pan-European radio telescope. From Leiden, Astronomer Timothy Shimwell and Huub Röttgering, among others, are involved. It reveals an astonishingly…
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.