1,131 search results for “acute and chronic stress” in the Public website
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About us
All living creatures have to cope with environmental demands and threats that challenge their physical or emotional homeostasis.
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models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Jin Yan
Faculteit der Sociale Wetenschappen
j.yan@fsw.leidenuniv.nl | +31 71 527 2727
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The 3Generation study: Stress and Emotions in a Family Context
What is the role of neuronal emotional reactivity in the intergenerational transmission of abuse?
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Mathematical modeling of cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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Even unconscious stress can cause stress symptoms
Our vision of stress is starting to change fundamentally. We can suffer stress without even being aware of it, while sleeping as wall as during the day. Professor of Psychology Jos Brosschot will discuss this phenomenon in his inaugural lecture on 2 December.
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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The rhizomicrobiome of Sorghum ; impact on plant growth and stress tolerance
The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Jessy Terpstra
Faculteit der Sociale Wetenschappen
j.a.terpstra@fsw.leidenuniv.nl | +31 71 527 2727
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From stress to success: how actinobacteria exploit life without a cell wall
The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.
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Harnessing the soil microbiome for improved stress tolerance in crop plants
Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?
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and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
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Rachel de Jong
Faculteit der Sociale Wetenschappen
r.de.jong@fsw.leidenuniv.nl | +31 71 527 2727
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Simone Vogelaar
Faculteit der Sociale Wetenschappen
s.vogelaar@fsw.leidenuniv.nl | +31 71 527 3830
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Veronique de Gucht
Faculteit der Sociale Wetenschappen
degucht@fsw.leidenuniv.nl | +31 71 527 3863
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Pascal Nuijten
Science
p.nuijten@biology.leidenuniv.nl | +31 71 527 4384
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Anne Versluis
Faculteit der Sociale Wetenschappen
a.w.e.versluis@fsw.leidenuniv.nl | +31 71 527 2727
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The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a pre-registered systematic
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.
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Different components of impulsivity in relation to emotional stress in patients with Borderline Personality Disorder and patients with Attention
How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?
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Research
How do people acquire language? How can you train your brain? What is the effect of stress on an unborn child? LIBC research topics range from language processing to cognitive robotics, and from psychiatric disorders to the impact of social factors on human behaviour. Meet several main research topics…
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Sofie Rasmussen
Science
a.s.b.rasmussen@cml.leidenuniv.nl | +31 71 527 2727
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Healthy Society
The theme 'Healthy Society' is one of the focal points of the Faculty of Social and Behavioural Sciences (FSW).
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Research
Although there has been an increase in the research into brain function and dysfunction in relation to stress and emotions, there are still many unanswered questions.
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What is the effect of long-term exposure to engineered nanomaterials (ENMS)?
Engineered nanomaterials (ENMs) are widely used, and nanotechnological innovations grow with rapid pace. Studies on nanotoxicology have demonstrated that chemical toxicology as well as particle toxicology should be accounted for in predicting the safety of ENMs.
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Students get advice on avoiding stress
A quarter of all Dutch students suffer burn-out symptoms, and an even greater percentage regularly experience emotional exhaustion and tiredness. At a symposium on 7 May students were given tips for handling stress.
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Jennifer Becker
Faculteit der Sociale Wetenschappen
j.m.becker@fsw.leidenuniv.nl | +31 71 527 2727
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Research
The Institute of Psychology is responsible for innovative and interdisciplinary research and education within psychology and related disciplines. It focuses primarily on four broad areas: Health and Wellbeing; Development and Learning; Socio-Cognitive-Affective Decision-making and Advanced Behavioural…
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HOPES Study
The HOPES study is one of the largest investigations of this kind to date! By studying existing brain scans and data collected form over 4,000 14-25 year olds, the project team hopes to identify specific changes in the brain that make young people vulnerable to suicidal thoughts and behaviours.
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The right to health of the child : an analytical exploration of the international normative framework
Large numbers of children all over the world face significant health risks, such as infectious and chronic diseases, malnutrition, injuries and the consequences of natural disasters, protracted armed conflicts and poverty.
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Vaccination against atherosclerosis; induction of protective CD8 T-cells through immunization
Atherosclerosis, in particular rupture of atherosclerotic plaques, is the underlying cause of most heart attacks or strokes and is the leading cause of death worldwide.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Roos van der Vaart
Faculteit der Sociale Wetenschappen
r.van.der.vaart@fsw.leidenuniv.nl | +31 71 527 2727
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Topic: E-health
The research connected to this topic is related to E-health.
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Marieke Tollenaar
Faculteit der Sociale Wetenschappen
m.s.tollenaar@fsw.leidenuniv.nl | +31 71 527 3454
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Leukemia treatment & cognitive development
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Innovative diagnostics and treatments
The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Laura Nawijn
Faculteit der Sociale Wetenschappen
l.nawijn@fsw.leidenuniv.nl | +31 71 527 2727
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Rüya Akdag
Faculteit der Sociale Wetenschappen
r.akdag@fsw.leidenuniv.nl | +31 71 527 2727